-
1
-
-
84921744345
-
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts
-
Keller J, Catala-Lehnen P, Huebner AK, et al. Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts. Nat Commun. 2014;5:5215 doi: 10.1038/ncomms6215
-
(2014)
Nat Commun
, vol.5
, pp. 5215
-
-
Keller, J.1
Catala-Lehnen, P.2
Huebner, A.K.3
-
2
-
-
43749083192
-
Evidence for calcitonin - A new hormone from the parathyroid that lowers blood calcium
-
Copp DH, Cameron EC, Cheney BA, Davidson AG, Henze KG. Evidence for calcitonin - a new hormone from the parathyroid that lowers blood calcium. Endocrinology. 1962;70:638-649.
-
(1962)
Endocrinology
, vol.70
, pp. 638-649
-
-
Copp, D.H.1
Cameron, E.C.2
Cheney, B.A.3
Davidson, A.G.4
Henze, K.G.5
-
4
-
-
85046177778
-
Thyrocalcitonin: Hypocalcemic hypophosphatemic principle of the thyroid gland
-
Hirsch PF, Voelkel EF, Munson PL. Thyrocalcitonin: hypocalcemic hypophosphatemic principle of the thyroid gland. Science. 1964;146:412-413.
-
(1964)
Science
, vol.146
, pp. 412-413
-
-
Hirsch, P.F.1
Voelkel, E.F.2
Munson, P.L.3
-
5
-
-
0013845778
-
Thyrocalcitonin: Inhibitor of bone resorption in tissue culture
-
Friedman J, Raisz LG. Thyrocalcitonin: inhibitor of bone resorption in tissue culture. Science. 1965;150:(702):1465-1467.
-
(1965)
Science
, vol.150
, Issue.702
, pp. 1465-1467
-
-
Friedman, J.1
Raisz, L.G.2
-
6
-
-
0014025630
-
The mode of action of thyrocalcitonin
-
Martin TJ, Robinson CJ, MacIntyre I. The mode of action of thyrocalcitonin. Lancet. 1966;1:(7443):900-902.
-
(1966)
Lancet
, vol.1
, Issue.7443
, pp. 900-902
-
-
Martin, T.J.1
Robinson, C.J.2
MacIntyre, I.3
-
7
-
-
0013915793
-
An inhibitory effect of thyrocalcitonin on calcium release in vivo and on bone metabolism in vitro
-
Johnston CC Jr, Deiss WP Jr. An inhibitory effect of thyrocalcitonin on calcium release in vivo and on bone metabolism in vitro. Endocrinology. 1966;78:(6):1139-1143.
-
(1966)
Endocrinology
, vol.78
, Issue.6
, pp. 1139-1143
-
-
Johnston, C.C.1
Deiss, W.P.2
-
8
-
-
0014126636
-
Mode of action of thyrocalcitonin
-
Robinson CJ, Martin TJ, Matthews EW, MacIntyre I. Mode of action of thyrocalcitonin. J Endocrinol. 1967;39:(1):71-79.
-
(1967)
J Endocrinol
, vol.39
, Issue.1
, pp. 71-79
-
-
Robinson, C.J.1
Martin, T.J.2
Matthews, E.W.3
MacIntyre, I.4
-
9
-
-
0022500788
-
Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization
-
Nicholson GC, Moseley JM, Sexton PM, Mendelsohn FA, Martin TJ. Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization. J Clin Invest. 1986;78:(2):355-360.
-
(1986)
J Clin Invest
, vol.78
, Issue.2
, pp. 355-360
-
-
Nicholson, G.C.1
Moseley, J.M.2
Sexton, P.M.3
Mendelsohn, F.A.4
Martin, T.J.5
-
10
-
-
0021179382
-
Effect of parathyroid hormone and calcitonin on the cytoplasmic spreading of isolated osteoclasts
-
Chambers TJ, Athanasou NA, Fuller K. Effect of parathyroid hormone and calcitonin on the cytoplasmic spreading of isolated osteoclasts. J Endocrinol. 1984;102:(3):281-286.
-
(1984)
J Endocrinol
, vol.102
, Issue.3
, pp. 281-286
-
-
Chambers, T.J.1
Athanasou, N.A.2
Fuller, K.3
-
11
-
-
29644434969
-
Calcitonin
-
Jamieson LJDJL, editor., New York: Elsevier
-
Martin TJ, Findlay DM, Sexton PM. Calcitonin. In: Jamieson LJDJL, editor., Endocrinology. New York: Elsevier. 2010; 1:pp 1419-1434.
-
(2010)
Endocrinology
, vol.1
, pp. 1419-1434
-
-
Martin, T.J.1
Findlay, D.M.2
Sexton, P.M.3
-
12
-
-
0141859931
-
Is calcitonin an important physiological substance?
-
Hirsch PF, Baruch H. Is calcitonin an important physiological substance? Endocrine. 2003;21:(3):201-208.
-
(2003)
Endocrine
, vol.21
, Issue.3
, pp. 201-208
-
-
Hirsch, P.F.1
Baruch, H.2
-
13
-
-
0036945790
-
Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene
-
Hoff AO, Catala-Lehnen P, Thomas PM, et al. Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene. J Clin Invest. 2002;110:(12):1849-1857.
-
(2002)
J Clin Invest
, vol.110
, Issue.12
, pp. 1849-1857
-
-
Hoff, A.O.1
Catala-Lehnen, P.2
Thomas, P.M.3
-
14
-
-
21644478747
-
Decreased bone formation and osteopenia in mice lacking alpha-calcitonin gene-related peptide
-
Schinke T, Liese S, Priemel M, et al. Decreased bone formation and osteopenia in mice lacking alpha-calcitonin gene-related peptide. J Bone Miner Res. 2004;19:(12):2049-2056.
-
(2004)
J Bone Miner Res
, vol.19
, Issue.12
, pp. 2049-2056
-
-
Schinke, T.1
Liese, S.2
Priemel, M.3
-
15
-
-
33845197721
-
Calcitonin deficiency in mice progressively results in high bone turnover
-
Huebner AK, Schinke T, Priemel M, et al. Calcitonin deficiency in mice progressively results in high bone turnover. J Bone Miner Res. 2006;21:(12):1924-1934.
-
(2006)
J Bone Miner Res
, vol.21
, Issue.12
, pp. 1924-1934
-
-
Huebner, A.K.1
Schinke, T.2
Priemel, M.3
-
16
-
-
10744220002
-
Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo
-
Dacquin R, Davey RA, Laplace C, et al. Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo. J Cell Biol. 2004;164:(4):509-514.
-
(2004)
J Cell Biol
, vol.164
, Issue.4
, pp. 509-514
-
-
Dacquin, R.1
Davey, R.A.2
Laplace, C.3
-
17
-
-
47849106349
-
The calcitonin receptor plays a physiological role to protect against hypercalcemia in mice
-
Davey RA, Turner A, McManus JF, et al. The calcitonin receptor plays a physiological role to protect against hypercalcemia in mice. J Bone Miner Res. 2008;23:(8):1182-1193.
-
(2008)
J Bone Miner Res
, vol.23
, Issue.8
, pp. 1182-1193
-
-
Davey, R.A.1
Turner, A.2
McManus, J.F.3
-
18
-
-
53349180215
-
The role of peptides and receptors of the calcitonin family in the regulation of bone metabolism
-
Naot D, Cornish J. The role of peptides and receptors of the calcitonin family in the regulation of bone metabolism. Bone. 2008;43:(5):813-818.
-
(2008)
Bone
, vol.43
, Issue.5
, pp. 813-818
-
-
Naot, D.1
Cornish, J.2
-
19
-
-
84899810047
-
Decline in calcitonin receptor expression in osteocytes with age
-
Gooi JH, Chia LY, Walsh NC, et al. Decline in calcitonin receptor expression in osteocytes with age. J Endocrinol. 2014;221:(2):181-191.
-
(2014)
J Endocrinol
, vol.221
, Issue.2
, pp. 181-191
-
-
Gooi, J.H.1
Chia, L.Y.2
Walsh, N.C.3
-
20
-
-
77952961232
-
Calcitonin impairs the anabolic effect of PTH in young rats and stimulates expression of sclerostin by osteocytes
-
Gooi JH, Pompolo S, Karsdal MA, et al. Calcitonin impairs the anabolic effect of PTH in young rats and stimulates expression of sclerostin by osteocytes. Bone. 2010;46:(6):1486-1497.
-
(2010)
Bone
, vol.46
, Issue.6
, pp. 1486-1497
-
-
Gooi, J.H.1
Pompolo, S.2
Karsdal, M.A.3
-
21
-
-
68849117424
-
Identification of differentially expressed genes between osteoblasts and osteocytes
-
Paic F, Igwe JC, Nori R, et al. Identification of differentially expressed genes between osteoblasts and osteocytes. Bone. 2009;45:(4):682-692.
-
(2009)
Bone
, vol.45
, Issue.4
, pp. 682-692
-
-
Paic, F.1
Igwe, J.C.2
Nori, R.3
-
22
-
-
42949130155
-
Procalcitonin has bioactivity at calcitonin receptor family complexes: Potential mediator implications in sepsis
-
Sexton PM, Christopoulos G, Christopoulos A, Nylen ES, Snider RH, Jr, Becker KL. Procalcitonin has bioactivity at calcitonin receptor family complexes: potential mediator implications in sepsis. Crit Care Med. 2008;36:(5):1637-1640.
-
(2008)
Crit Care Med
, vol.36
, Issue.5
, pp. 1637-1640
-
-
Sexton, P.M.1
Christopoulos, G.2
Christopoulos, A.3
Nylen, E.S.4
Snider, R.H.5
Becker, K.L.6
-
23
-
-
0035140323
-
Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis
-
Muller B, White JC, Nylen ES, Snider RH, Becker KL, Habener JF. Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis. J Clin Endocrinol Metab. 2001;86:(1):396-404.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, Issue.1
, pp. 396-404
-
-
Muller, B.1
White, J.C.2
Nylen, E.S.3
Snider, R.H.4
Becker, K.L.5
Habener, J.F.6
-
24
-
-
0031776575
-
Mortality is increased by procalcitonin and decreased by an antiserum reactive to procalcitonin in experimental sepsis
-
Nylen ES, Whang KT, Snider RH, Jr, Steinwald PM, White JC, Becker KL. Mortality is increased by procalcitonin and decreased by an antiserum reactive to procalcitonin in experimental sepsis. Crit Care Med. 1998;26:(6):1001-1006.
-
(1998)
Crit Care Med
, vol.26
, Issue.6
, pp. 1001-1006
-
-
Nylen, E.S.1
Whang, K.T.2
Snider, R.H.3
Steinwald, P.M.4
White, J.C.5
Becker, K.L.6
-
25
-
-
58549115903
-
Regulation of bone formation by osteoclasts involves Wnt/BMP signaling the chemokine sphingosine-1-phosphate
-
Pederson L, Ruan M, Westendorf JJ, Khosla S, Oursler MJ. Regulation of bone formation by osteoclasts involves Wnt/BMP signaling the chemokine sphingosine-1-phosphate. Proc Natl Acad Sci USA. 2008;105:(52):20764-20769.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.52
, pp. 20764-20769
-
-
Pederson, L.1
Ruan, M.2
Westendorf, J.J.3
Khosla, S.4
Oursler, M.J.5
-
26
-
-
33845714356
-
Sphingosine 1-phosphate as a regulator of osteoclast differentiation osteoclast-osteoblast coupling
-
Ryu J, Kim HJ, Chang EJ, Huang H, Banno Y, Kim HH. Sphingosine 1-phosphate as a regulator of osteoclast differentiation osteoclast-osteoblast coupling. Embo J. 2006;25:(24):5840-5851.
-
(2006)
Embo J
, vol.25
, Issue.24
, pp. 5840-5851
-
-
Ryu, J.1
Kim, H.J.2
Chang, E.J.3
Huang, H.4
Banno, Y.5
Kim, H.H.6
-
27
-
-
84873401233
-
Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation
-
Lotinun S, Kiviranta R, Matsubara T, et al. Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation. J Clin Invest. 2013;123:(2):666-681.
-
(2013)
J Clin Invest
, vol.123
, Issue.2
, pp. 666-681
-
-
Lotinun, S.1
Kiviranta, R.2
Matsubara, T.3
-
28
-
-
84895922168
-
Coupling the activities of bone formation and resorption: A multitude of signals within the basic multicellular unit
-
Sims NA, Martin TJ. Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit. Bonekey Rep. 2014;3:481.
-
(2014)
Bonekey Rep
, vol.3
, pp. 481
-
-
Sims, N.A.1
Martin, T.J.2
-
29
-
-
84903287192
-
Coupling factors: How many candidates can there be?
-
Martin TJ. Coupling factors: how many candidates can there be? J Bone Miner Res. 2014;29:(7):1519-1521.
-
(2014)
J Bone Miner Res
, vol.29
, Issue.7
, pp. 1519-1521
-
-
Martin, T.J.1
-
30
-
-
84866161266
-
Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength
-
Bassett JH, Gogakos A, White JK, et al. Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength. PLoS Genet. 2012;8:(8):e1002858.
-
(2012)
PLoS Genet
, vol.8
, Issue.8
, pp. e1002858
-
-
Bassett, J.H.1
Gogakos, A.2
White, J.K.3
-
31
-
-
84859727262
-
The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice
-
Fukuhara S, Simmons S, Kawamura S, et al. The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. J Clin Invest. 2012;122:(4):1416-1426.
-
(2012)
J Clin Invest
, vol.122
, Issue.4
, pp. 1416-1426
-
-
Fukuhara, S.1
Simmons, S.2
Kawamura, S.3
-
32
-
-
84907218143
-
Fingolimod for the treatment of neurological diseases - State of play and future perspectives
-
Brunkhorst R, Vutukuri R, Pfeilschifter W. Fingolimod for the treatment of neurological diseases - state of play and future perspectives. Front Cell Neurosci. 2014;8:283.
-
(2014)
Front Cell Neurosci
, vol.8
, pp. 283
-
-
Brunkhorst, R.1
Vutukuri, R.2
Pfeilschifter, W.3
-
33
-
-
1642580757
-
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
-
Matloubian M, Lo CG, Cinamon G, et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature. 2004;427:(6972):355-360.
-
(2004)
Nature
, vol.427
, Issue.6972
, pp. 355-360
-
-
Matloubian, M.1
Lo, C.G.2
Cinamon, G.3
-
34
-
-
84908504987
-
Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells
-
Brizuela L, Martin C, Jeannot P, et al. Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells. Mol Oncol. 2014;8:(7):1181-1195.
-
(2014)
Mol Oncol
, vol.8
, Issue.7
, pp. 1181-1195
-
-
Brizuela, L.1
Martin, C.2
Jeannot, P.3
-
35
-
-
84904250638
-
S1P control of endothelial integrity
-
Xiong Y, Hla T. S1P control of endothelial integrity. Curr Top Microbiol Immunol. 2014;378:85-105.
-
(2014)
Curr Top Microbiol Immunol
, vol.378
, pp. 85-105
-
-
Xiong, Y.1
Hla, T.2
-
36
-
-
0037216604
-
Linking Chinese medicine and G-protein-coupled receptors
-
Im DS. Linking Chinese medicine and G-protein-coupled receptors. Trends Pharmacol Sci. 2003;24:(1):2-4.
-
(2003)
Trends Pharmacol Sci
, vol.24
, Issue.1
, pp. 2-4
-
-
Im, D.S.1
-
37
-
-
80052781117
-
Potential mechanisms of efficacy and adverse effects in the use of fingolimod (FTY720)
-
Ontaneda D, Cohen JA. Potential mechanisms of efficacy and adverse effects in the use of fingolimod (FTY720). Exp Rev Clin Pharmacol. 2011;4:(5):567-570.
-
(2011)
Exp Rev Clin Pharmacol
, vol.4
, Issue.5
, pp. 567-570
-
-
Ontaneda, D.1
Cohen, J.A.2
-
38
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
-
Brinkmann V, Davis MD, Heise CE, et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J Biol Chem. 2002;277:(24):21453-21457.
-
(2002)
J Biol Chem
, vol.277
, Issue.24
, pp. 21453-21457
-
-
Brinkmann, V.1
Davis, M.D.2
Heise, C.E.3
-
39
-
-
84862682840
-
Sphingosine 1-phosphate receptor activation enhances BMP-2-induced osteoblast differentiation
-
Sato C, Iwasaki T, Kitano S, Tsunemi S, Sano H. Sphingosine 1-phosphate receptor activation enhances BMP-2-induced osteoblast differentiation. Biochem Biophys Res Commun. 2012;423:(1):200-205.
-
(2012)
Biochem Biophys Res Commun
, vol.423
, Issue.1
, pp. 200-205
-
-
Sato, C.1
Iwasaki, T.2
Kitano, S.3
Tsunemi, S.4
Sano, H.5
-
40
-
-
77953963056
-
The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720
-
Petrie Aronin CE, Shin SJ, Naden KB, et al. The enhancement of bone allograft incorporation by the local delivery of the sphingosine 1-phosphate receptor targeted drug FTY720. Biomaterials. 2010;31:(25):6417-6424.
-
(2010)
Biomaterials
, vol.31
, Issue.25
, pp. 6417-6424
-
-
Petrie Aronin, C.E.1
Shin, S.J.2
Naden, K.B.3
-
41
-
-
77953339728
-
FTY720 promotes local microvascular network formation, regeneration of cranial bone defects
-
Petrie Aronin CE, Sefcik LS, Tholpady SS, et al. FTY720 promotes local microvascular network formation, regeneration of cranial bone defects. Tissue Eng Part A. 2010;16:(6):1801-1809.
-
(2010)
Tissue Eng Part A
, vol.16
, Issue.6
, pp. 1801-1809
-
-
Petrie Aronin, C.E.1
Sefcik, L.S.2
Tholpady, S.S.3
-
42
-
-
84884901062
-
Systemic treatment with the sphingosine-1-phosphate analog FTY720 does not improve fracture healing in mice
-
Heilmann A, Schinke T, Bindl R, et al. Systemic treatment with the sphingosine-1-phosphate analog FTY720 does not improve fracture healing in mice. J Orthop Res. 2013;31:(11):1845-1850.
-
(2013)
J Orthop Res
, vol.31
, Issue.11
, pp. 1845-1850
-
-
Heilmann, A.1
Schinke, T.2
Bindl, R.3
-
43
-
-
63649143900
-
Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis
-
Ishii M, Egen JG, Klauschen F, et al. Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis. Nature. 2009;458:(7237):524-528.
-
(2009)
Nature
, vol.458
, Issue.7237
, pp. 524-528
-
-
Ishii, M.1
Egen, J.G.2
Klauschen, F.3
-
44
-
-
78650413566
-
Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo
-
Ishii M, Kikuta J, Shimazu Y, Meier-Schellersheim M, Germain RN. Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo. J Exp Med. 2010;207:(13):2793-2798.
-
(2010)
J Exp Med
, vol.207
, Issue.13
, pp. 2793-2798
-
-
Ishii, M.1
Kikuta, J.2
Shimazu, Y.3
Meier-Schellersheim, M.4
Germain, R.N.5
-
45
-
-
84861307742
-
Twenty-five years of PTHrP progress: From cancer hormone to multifunctional cytokine
-
McCauley LK, Martin TJ. Twenty-five years of PTHrP progress: from cancer hormone to multifunctional cytokine. J Bone Miner Res. 2012;27:(6):1231-1239.
-
(2012)
J Bone Miner Res
, vol.27
, Issue.6
, pp. 1231-1239
-
-
McCauley, L.K.1
Martin, T.J.2
-
46
-
-
4644312198
-
Reference intervals for serum calcitonin in men, women, and children
-
Basuyau JP, Mallet E, Leroy M, Brunelle P. Reference intervals for serum calcitonin in men, women, and children. Clin Chem. 2004;50:(10):1828-1830.
-
(2004)
Clin Chem
, vol.50
, Issue.10
, pp. 1828-1830
-
-
Basuyau, J.P.1
Mallet, E.2
Leroy, M.3
Brunelle, P.4
-
48
-
-
13244267455
-
Osteoclast-derived activity in the coupling of bone formation to resorption
-
Martin TJ, Sims NA. Osteoclast-derived activity in the coupling of bone formation to resorption. Trends Mol Med. 2005;11:(2):76-81.
-
(2005)
Trends Mol Med
, vol.11
, Issue.2
, pp. 76-81
-
-
Martin, T.J.1
Sims, N.A.2
|