Targeted delivery of 5-fluorouracil to HT-29 cells using high efficient folic acid-conjugated nanoparticles

Drug Delivery

Volumn 22, Issue 2, 2015, Pages 191-198

  Wang, Yichao ^a   Li, Puwang ^a,b   Chen, Lijue ^a   Gao, Weimin ^a   Zeng, Fanbo ^c   Kong, Ling Xue ^a  

^a DEAKIN UNIVERSITY   (Australia)

^b INSTITUTE OF TROPICAL BIOSCIENCE AND BIOTECHNOLOGY   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

3 diaminopropane folic acid; HT 29; Nanoparticles; PLGA 1; Targeting

Indexed keywords

1,3 PROPANEDIAMINE; BIOMATERIAL; FLUOROURACIL; FOLIC ACID; NANOPARTICLE; POLYGLACTIN; ANTINEOPLASTIC ANTIMETABOLITE; CROSS LINKING REAGENT; DIAMINE; DRUG CARRIER; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ARTICLE; BINDING AFFINITY; CELL VIABILITY; CHEMICAL COMPOSITION; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG TARGETING; DRUG UPTAKE; FLUORESCENCE MICROSCOPY; HT 29 CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; NANOENCAPSULATION; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; ZETA POTENTIAL; ADENOCARCINOMA; CELL SURVIVAL; CHEMISTRY; COLONIC NEOPLASMS; COMPARATIVE STUDY; DRUG EFFECTS; KINETICS; METABOLISM; PATHOLOGY; SURFACE PROPERTY; TRANSPORT AT THE CELLULAR LEVEL;

ADENOCARCINOMA; ANTIMETABOLITES, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; CELL SURVIVAL; COLONIC NEOPLASMS; CROSS-LINKING REAGENTS; DIAMINES; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; FLUOROURACIL; FOLIC ACID; HT29 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; LACTIC ACID; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; POLYGLYCOLIC ACID; SURFACE PROPERTIES;

EID: 84921693599     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2013.875603     Document Type: Article

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