A straightforward, quantitative ultra-performance liquid chromatography-tandem mass spectrometric method for heparan sulfate, dermatan sulfate and chondroitin sulfate in urine: An improved clinical screening test for the mucopolysaccharidoses

Molecular Genetics and Metabolism

Volumn 114, Issue 2, 2015, Pages 123-128

  Zhang, Haoyue ^a   Wood, Tim ^b   Young, Sarah P ^a   Millington, David S ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GREENWOOD GENETIC CENTER   (United States)

Author keywords

Glycosaminoglycans; Methanolysis; Mucopolysaccharidoses; Screening; UPLC MS MS; Urine

Indexed keywords

CHONDROITIN SULFATE; DERMATAN SULFATE; HEPARAN SULFATE; IDURONIC ACID N GLUCOSAMINE; STABLE ISOTOPE; UNCLASSIFIED DRUG; URONIC ACID; URONIC ACID N ACETYLHEXOSAMINE; GLYCOSAMINOGLYCAN;

ACCURACY; ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; ELECTROSPRAY MASS SPECTROMETRY; GROUPS BY AGE; HUMAN; INFANT; ISOTOPE DILUTION ASSAY; LIMIT OF QUANTITATION; METHANOLYSIS; MUCOPOLYSACCHARIDOSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REFERENCE VALUE; SCREENING TEST; SENSITIVITY AND SPECIFICITY; STANDARD; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; URINALYSIS; LIQUID CHROMATOGRAPHY; MIDDLE AGED; MORQUIO SYNDROME; MUCOPOLYSACCHARIDOSES; MUCOPOLYSACCHARIDOSIS II; MUCOPOLYSACCHARIDOSIS III; MUCOPOLYSACCHARIDOSIS VI; PRESCHOOL CHILD; PROCEDURES; URINE; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; CHILD; CHILD, PRESCHOOL; CHONDROITIN SULFATES; CHROMATOGRAPHY, LIQUID; DERMATAN SULFATE; GLYCOSAMINOGLYCANS; HEPARITIN SULFATE; HUMANS; INFANT; MIDDLE AGED; MUCOPOLYSACCHARIDOSES; MUCOPOLYSACCHARIDOSIS II; MUCOPOLYSACCHARIDOSIS III; MUCOPOLYSACCHARIDOSIS IV; MUCOPOLYSACCHARIDOSIS VI; RADIOISOTOPE DILUTION TECHNIQUE; REFERENCE VALUES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; YOUNG ADULT;

EID: 84921681670     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2014.09.009     Document Type: Article

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