Application of a sensitive and specific LC-MS/MS method for determination of eriodictyol-8-C-β-d-glucopyranoside in rat plasma for a bioavailability study

Biomedical Chromatography

Volumn 29, Issue 2, 2015, Pages 220-225

  Qiu, Feng ^a   Fu, Shujun ^b   Zhang, Xinshi ^c   Gong, Muxin ^a   Wang, Manyuan ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c HEBEI NORTH UNIVERSITY   (China)

Author keywords

Chirita longgangensis; Eriodictyol 8 C d glucopyranoside; LC ESI MS MS; Pharmacokinetics; Rat

Indexed keywords

BIOCHEMISTRY; BODY FLUIDS; ELECTROSPRAY IONIZATION; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRECIPITATION (CHEMICAL);

BIOAVAILABILITY STUDY; CHIRITUM LONGGANGENSIS; ERIODICTYOL-8-C-Β-D-GLUCOPYRANOSIDE; GLUCOPYRANOSIDE; INTERNAL STANDARDS; LC MS/MS(ESI); LC-ESI-MS/MS; LC-MS-MS; LC/ESI-MS/MS; RAT PLASMA;

RATS;

ACETONITRILE; ERIODICTYOL 8 C BETA DEXTRO GLUCOPYRANOSIDE; FORMIC ACID; GLUCOPYRANOSIDE; UNCLASSIFIED DRUG; FLAVANONE DERIVATIVE; GLUCOSIDE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG HALF LIFE; ELECTROSPRAY NEGATIVE IONIZATION MASS SPECTROMETRY; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; RAT; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; VOLUME OF DISTRIBUTION AT STEADY-STATE; ANIMAL; BLOOD; ELECTROSPRAY MASS SPECTROMETRY; PROCEDURES; REPRODUCIBILITY; SPRAGUE DAWLEY RAT;

CHIRITA LONGGANGENSIS; RATTUS;

ANIMALS; CHROMATOGRAPHY, LIQUID; FLAVANONES; GLUCOSIDES; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84921617049     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.3263     Document Type: Article

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