Treating thrombosis in cirrhosis patients with new oral agents: Ready or not?

Hepatology

Volumn 61, Issue 2, 2015, Pages 738-739

  Intagliata, Nicolas M ^a   Maitland, Hillary ^a   Northup, Patrick G ^a   Caldwell, Stephen H ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APIXABAN; RIVAROXABAN; WARFARIN; ANTICOAGULANT AGENT; MORPHOLINE DERIVATIVE; THIOPHENE DERIVATIVE;

ADULT; AGED; ANTICOAGULANT THERAPY; ANTIPHOSPHOLIPID SYNDROME; AUTOIMMUNE HEPATITIS; CHILD TURCOTTE PUGH SCORE; CLINICAL ARTICLE; ESOPHAGUS VARICES; FEMALE; HUMAN; LETTER; LIVER CIRRHOSIS; MALE; MESENTERIC VEIN THROMBOSIS; MIDDLE AGED; NONALCOHOLIC FATTY LIVER; OUTCOME ASSESSMENT; PORTAL VEIN THROMBOSIS; PRIORITY JOURNAL; SUPERIOR MESENTERIC VEIN THROMBOSIS; MESENTERIC VEIN; PORTAL VEIN; VENOUS THROMBOSIS;

ANTICOAGULANTS; HUMANS; MALE; MESENTERIC VEINS; MORPHOLINES; PORTAL VEIN; THIOPHENES; VENOUS THROMBOSIS;

EID: 84921612452     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27225     Document Type: Letter

References (4)

1. Martinez M, Tandra A, Vuppalanchi R. Treatment of acute portal vein thrombosis by non-traditional anticoagulation. Hepatology 2014;60:425-426.
2. Villa E, Camma C, Marietta M, Luongo M, Critelli R, Colopi S, et al. Enoxaparin prevents portal vein thrombosis and liver decompensation in patients with advanced cirrhosis. Gastroenterology 2012;143:1253-1260 e1251-1254.
3. Potze W, Arshad F, Adelmeijer J, Blokzijl H, van den Berg AP, Meijers JC, et al. Differential in vitro inhibition of thrombin generation by anticoagulant drugs in plasma from patients with cirrhosis. PLoS One 2014;9:e88390.
4. Kubitza D, Roth A, Becka M, Alatrach A, Halabi A, Hinrichsen H, et al. Effect of hepatic impairment on the pharmacokinetics and pharmacodynamics of a single dose of rivaroxaban, an oral, direct Factor Xa inhibitor. Br J Clin Pharmacol 2013;76:89-98.