Importance of viruses in acute otitis media

Current Opinion in Pediatrics

Volumn 27, Issue 1, 2015, Pages 110-115

  Nokso Koivisto, Johanna ^a   Marom, Tal ^b   Chonmaitree, Tasnee ^c  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b TEL AVIV UNIVERSITY   (Israel)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

acute otitis media; respiratory syncytial virus; respiratory viruses; rhinoviruses; viral bacterial interactions

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; INFLUENZA VACCINE; OSELTAMIVIR; PNEUMOCOCCUS VACCINE; RESPIRATORY SYNCYTIAL VIRUS VACCINE; VIRUS VACCINE;

ACUTE OTITIS MEDIA; ADENOVIRIDAE; BACTERIAL COLONIZATION; BACTERIAL LOAD; CORONAVIRUS; DISEASE ASSOCIATION; DISEASE COURSE; HEALTH CARE UTILIZATION; HUMAN; HUMAN BOCAVIRUS; HUMAN METAPNEUMOVIRUS; HUMAN RESPIRATORY SYNCYTIAL VIRUS; MOLECULAR DIAGNOSTICS; MORAXELLA CATARRHALIS; NONTYPEABLE HAEMOPHILUS INFLUENZAE; PARAINFLUENZA VIRUS; PATHOGENESIS; PRIORITY JOURNAL; RESPIRATORY VIRUS; REVIEW; RHINOVIRUS; RISK FACTOR; STREPTOCOCCUS PNEUMONIAE; UPPER RESPIRATORY TRACT INFECTION; VIRUS DETECTION; VIRUS LOAD; CHILD; MICROBIOLOGY; NASAL LAVAGE FLUID; OTITIS MEDIA; PATHOPHYSIOLOGY; PHARYNX DISEASE; PRESCHOOL CHILD; PREVALENCE; RESPIRATORY TRACT INFECTION; VIROLOGY; VIRUS INFECTION;

CHILD; CHILD, PRESCHOOL; HUMANS; NASAL LAVAGE FLUID; NASOPHARYNGEAL DISEASES; OTITIS MEDIA; PREVALENCE; RESPIRATORY TRACT INFECTIONS; VIRUS DISEASES;

EID: 84921549590     PISSN: 10408703     EISSN: 1531698X     Source Type: Journal    
DOI: 10.1097/MOP.0000000000000184     Document Type: Review

References (36)

1. Chonmaitree T, Revai K, Grady JJ, et al. Viral upper respiratory tract infection and otitis media complication in young children. Clin Infect Dis 2008; 46:815-823
2. Kalu SU, Ataya RS, McCormick DP, et al. Clinical spectrum of acute otitis media complicating upper respiratory tract viral infection. Pediatr Infect Dis J 2011; 30:95-99
3. Grijalva CG, Nuorti JP, Griffin MR. Antibiotic prescription rates for acute respiratory tract infections in US ambulatory settings. JAMA 2009; 302:758-766
4. Marom T, Tan A, Wilkinson GS, et al. Trends in otitis media-related healthcare use in the United States, 2001-2011. JAMA Pediatr 2014; 168:68-75
5. Lieberthal AS, Carroll AE, Chonmaitree T, et al. The diagnosis and management of acute otitis media. Pediatrics 2013; 131:e964-e999
6. Block SL, Heikkinen T, Toback SL, et al. The efficacy of live attenuated influenza vaccine against influenza-associated acute otitis media in children. Pediatr Infect Dis J 2011; 30:203-207
7. Heikkinen T, Block SL, Toback SL, et al. Effectiveness of intranasal live attenuated influenza vaccine against all-cause acute otitis media in children. Pediatr Infect Dis J 2013; 32:669-674
8. Heinonen S, Silvennoinen H, Lehtinen P, et al. Early oseltamivir treatment of influenza in children 1-3 years of age: a randomized controlled trial. Clin Infect Dis 2010; 51:887-894
9. Winther B, Block SL, Reisinger K, Dutkowski R. Impact of oseltamivir treatment on the incidence and course of acute otitis media in children with influenza. Int J Pediatr Otorhinolaryngol 2010; 74:684-688
10. Bialek SR, Allen D, Alvarado-Ramy F, et al. First confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the United States, updated information on the epidemiology of MERS-CoV infection, and guidance for the public, clinicians, and public health authorities: May 2014. MMWR Morb Mortal Wkly Rep 2014; 63:431-436
11. Yin JK, Salkeld G, Lambert SB, et al. Estimates and determinants of economic impacts from influenza-like illnesses caused by respiratory viruses in Australian children attending childcare: a cohort study. Influenza Other Respir Viruses 2013; 7:1103-1112
12. Marom T, Alvarez-Fernandez PE, Jennings K, et al. Acute bacterial sinusitis complicating viral upper respiratory tract infection in young children. Pediatr Infect Dis J 2014; 33:803-808
13. Ede LC, Loeffelholz MJ, Alvarez-Fernandez P, et al. Effect of the 2009 influenza A/H1N1 pandemic on viral respiratory infections in the first year of life. Pediatr Infect Dis J 2012; 31:1107-1112
14. Adams O, Weis J, Jasinska K, et al. Comparison of human metapneumovirus, respiratory syncytial virus and rhinovirus respiratory tract infections in young children admitted to hospital. J Med Virol 2014; doi: 10.1002/jmv.24025. [Epub ahead of print
15. Meriluoto M, Hedman L, Tanner L, et al. Association of human bocavirus 1 infection with respiratory disease in childhood follow-up study, Finland. Emerg Infect Dis 2012; 18:264-271
16. Nokso-Koivisto J, Pyles RB, Miller AL, et al. Viral load and acute otitis media development after human metapneumovirus upper respiratory tract infection. Pediatr Infect Dis J 2012; 31:763-766
17. Nokso-Koivisto JPR, Miller A, Jennings K, et al. Role of human bocavirus in upper respiratory tract infections and acute otitis media. J Pediatr Infect Dis Soc 2014; 3:98-103
18. Verhoeven D, Xu Q, Pichichero ME. Differential impact of respiratory syncytial virus and parainfluenza virus on the frequency of acute otitis media is explained by lower adaptive and innate immune responses in otitis-prone children. Clin Infect Dis 2014; 59:376-383
19. Ruohola A, Pettigrew MM, Lindholm L, et al. Bacterial and viral interactions within the nasopharynx contribute to the risk of acute otitis media. J Infect 2013; 66:247-254
20. Pettigrew MM, Gent JF, Pyles RB, et al. Viral-bacterial interactions and risk of acute otitis media complicating upper respiratory tract infection. J Clin Microbiol 2011; 49:3750-3755
21. Ruohola A, Meurman O, Nikkari S, et al. Microbiology of acute otitis media in children with tympanostomy tubes: prevalences of bacteria and viruses. Clin Infect Dis 2006; 43:1417-1422
22. Revai K, Dobbs LA, Nair S, et al. Incidence of acute otitis media and sinusitis complicating upper respiratory tract infection: the effect of age. Pediatrics 2007; 119:e1408-e1412
23. Wiertsema SP, Chidlow GR, Kirkham LA, et al. High detection rates of nucleic acids of a wide range of respiratory viruses in the nasopharynx and the middle ear of children with a history of recurrent acute otitis media. J Med Virol 2011; 83:2008-2017
24. Nokso-Koivisto J, Räty R, Blomqvist S, et al. Presence of specific viruses in the middle ear fluids and respiratory secretions of young children with acute otitis media. J Med Virol 2004; 72:241-248
25. Heikkinen T, Thint M, Chonmaitree T. Prevalence of various respiratory viruses in the middle ear during acute otitis media. N Engl J Med 1999; 340:260-264
26. Stockmann C, Ampofo K, Hersh AL, et al. Seasonality of acute otitis media and the role of respiratory viral activity in children. Pediatr Infect Dis J 2013; 32:314-319
27. Chonmaitree T, Alvarez-Fernandez PE, Kristofer K, et al. Symptomatic and asymptomatic respiratory viral infections in the first year of life: association with acute otitis media. Clin Infect Dis 2014; pii: ciu714. [Epub ahead of print
28. Patel JA, Nair S, Revai K, et al. Association of proinflammatory cytokine gene polymorphisms with susceptibility to otitis media. Pediatrics 2006; 118:2273-2279
29. Revai K, Patel JA, Grady JJ, et al. Association between cytokine gene polymorphisms and risk for upper respiratory tract infection and acute otitis media. Clin Infect Dis 2009; 49:257-261
30. Alper CM, Winther B, Hendley JO, Doyle WJ. Cytokine polymorphisms predict the frequency of otitis media as a complication of rhinovirus and RSV infections in children. Eur Arch Otorhinolaryngol 2009; 266:199-205
31. Emonts M, Veenhoven RH, Wiertsema SP, et al. Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. Pediatrics 2007; 120:814-823
32. Nokso-Koivisto J, Chonmaitree T, Jennings K, et al. Polymorphisms of immunity genes and susceptibility to otitis media in children. PLoS One 2014; 9:e93930
33. Marom T, Nokso-Koivisto J, Chonmaitree T. Viral-bacterial interactions in acute otitis media. Curr Allergy Asthma Rep 2012; 12:551-558
34. Binks MJ, Cheng AC, Smith-Vaughan H, et al. Viral -bacterial co-infection in Australian Indigenous children with acute otitis media. BMC Infect Dis 2011; 11:161
35. Hoberman A, Paradise JL, Rockette HE, et al. Treatment of acute otitis media in children under 2 years of age. N Engl J Med 2011; 364:105-115
36. Tähtinen PA, Laine MK, Huovinen P, et al. A placebo-controlled trial of antimicrobial treatment for acute otitis media. N Engl J Med 2011; 364:116-126