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Volumn 121, Issue 3, 2015, Pages 335-338

Targeted survival improvements in clinical trials: Are you an absolutist or relativist?

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL ERROR; CLINICAL TRIAL (TOPIC); DATA PROCESSING; EDITORIAL; FOLLOW UP; HAZARD RATIO; OUTCOME ASSESSMENT; OVARY CARCINOMA; OVERALL SURVIVAL; PROGRESSION FREE SURVIVAL; PROPORTIONAL HAZARDS MODEL; RESTRICTED MEAN SURVIVAL TIME; SAMPLE SIZE; STATISTICAL ANALYSIS; STUDY DESIGN; SURVIVAL TIME; FEMALE; HUMAN; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PHASE 3 CLINICAL TRIAL (TOPIC); PROCEDURES; RANDOMIZED CONTROLLED TRIAL (TOPIC); STATISTICS AND NUMERICAL DATA;

EID: 84921523837     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.29031     Document Type: Editorial
Times cited : (2)

References (12)
  • 1
    • 84921512499 scopus 로고    scopus 로고
    • Estimation of expectedness: Predictive accuracy of standard therapy outcomes in randomized phase 3 studies in epithelial ovarian cancer
    • Castonguay V, Wilson M, Diaz-Padilla I, Wang L, Oza A. Estimation of expectedness: predictive accuracy of standard therapy outcomes in randomized phase 3 studies in epithelial ovarian cancer. Cancer. 2015;121:413-422.
    • (2015) Cancer , vol.121 , pp. 413-422
    • Castonguay, V.1    Wilson, M.2    Diaz-Padilla, I.3    Wang, L.4    Oza, A.5
  • 2
    • 84900409159 scopus 로고    scopus 로고
    • Assessing methods to specify the target difference for a randomised controlled trial: DELTA (Difference ELicitation in TriAls) review
    • Cook JA, Hislop J, Adewuyi TE, et al. Assessing methods to specify the target difference for a randomised controlled trial: DELTA (Difference ELicitation in TriAls) review. Health Technol Assess. 2014;18:v-vi, 1-175.
    • (2014) Health Technol Assess , vol.18 , Issue.5-6 , pp. 1-175
    • Cook, J.A.1    Hislop, J.2    Adewuyi, T.E.3
  • 3
    • 84899911233 scopus 로고    scopus 로고
    • American Society of Clinical Oncology perspective: Raising the bar for clinical trials by defining clinically meaningful outcomes
    • Ellis LM, Bernstein DS, Voest EE, et al. American Society of Clinical Oncology perspective: raising the bar for clinical trials by defining clinically meaningful outcomes. J Clin Oncol. 2014;32:1277-1280.
    • (2014) J Clin Oncol , vol.32 , pp. 1277-1280
    • Ellis, L.M.1    Bernstein, D.S.2    Voest, E.E.3
  • 4
    • 84860121016 scopus 로고    scopus 로고
    • Assumptions of expected benefits in randomized phase III trials evaluating systemic treatments for cancer
    • Gan HK, You B, Pond GR, Chen EX. Assumptions of expected benefits in randomized phase III trials evaluating systemic treatments for cancer. J Natl Cancer Inst. 2012;104:590-598.
    • (2012) J Natl Cancer Inst , vol.104 , pp. 590-598
    • Gan, H.K.1    You, B.2    Pond, G.R.3    Chen, E.X.4
  • 5
    • 84855466019 scopus 로고    scopus 로고
    • A phase 3 trial of bevacizumab in ovarian cancer
    • Perren T, Swart A, Pfisterer J, et al; ICON7 Investigators. A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med. 2011;365:2484-2496.
    • (2011) N Engl J Med , vol.365 , pp. 2484-2496
    • Perren, T.1    Swart, A.2    Pfisterer, J.3
  • 6
    • 84873328631 scopus 로고    scopus 로고
    • Bevacizumab in stage II-III colon cancer: 5-year update of the National Surgical Adjuvant Breast and Bowel Project C-08 trial
    • Allegra CJ, Yothers G, O'Connell MJ, et al. Bevacizumab in stage II-III colon cancer: 5-year update of the National Surgical Adjuvant Breast and Bowel Project C-08 trial. J Clin Oncol. 2013;31:359-364.
    • (2013) J Clin Oncol , vol.31 , pp. 359-364
    • Allegra, C.J.1    Yothers, G.2    O'Connell, M.J.3
  • 7
    • 84885836084 scopus 로고    scopus 로고
    • Late divergence of survival curves in cancer immunotherapy trials: Interpretation and implications
    • Thoren FB, Anderson H, Strannegard O. Late divergence of survival curves in cancer immunotherapy trials: interpretation and implications. Cancer Immunol Immunother. 2013;62:1547-1551.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 1547-1551
    • Thoren, F.B.1    Anderson, H.2    Strannegard, O.3
  • 8
    • 84905841420 scopus 로고    scopus 로고
    • Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis
    • Uno H, Claggett B, Tian L, et al. Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis. J Clin Oncol. 2014;32:2380-2385.
    • (2014) J Clin Oncol , vol.32 , pp. 2380-2385
    • Uno, H.1    Claggett, B.2    Tian, L.3
  • 9
    • 84889006409 scopus 로고    scopus 로고
    • Restricted mean survival time: An alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome
    • Royston P, Parmar MK. Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome. BMC Med Res Methodol. 2013;13:152.
    • (2013) BMC Med Res Methodol , vol.13 , pp. 152
    • Royston, P.1    Parmar, M.K.2
  • 10
    • 84858449958 scopus 로고    scopus 로고
    • A practical comparison of blinded methods for sample size reviews in survival data clinical trials
    • Todd S, Valdes-Marquez E, West J. A practical comparison of blinded methods for sample size reviews in survival data clinical trials. Pharm Stat. 2012;11:141-148.
    • (2012) Pharm Stat , vol.11 , pp. 141-148
    • Todd, S.1    Valdes-Marquez, E.2    West, J.3
  • 11
    • 84864004759 scopus 로고    scopus 로고
    • Overall survival: Patient outcome, therapeutic objective, clinical trial end point, or public health measure?
    • Saad ED, Buyse M. Overall survival: patient outcome, therapeutic objective, clinical trial end point, or public health measure? J Clin Oncol. 2012;30:1750-1754.
    • (2012) J Clin Oncol , vol.30 , pp. 1750-1754
    • Saad, E.D.1    Buyse, M.2
  • 12
    • 84860496547 scopus 로고    scopus 로고
    • Progression-free survival: Meaningful or simply measurable?
    • Booth CM, Eisenhauer EA. Progression-free survival: meaningful or simply measurable? J Clin Oncol. 2012;30:1030-1033.
    • (2012) J Clin Oncol , vol.30 , pp. 1030-1033
    • Booth, C.M.1    Eisenhauer, E.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.