Effects of sublingual immunotherapy on serum IL-17 and IL-35 levels in children with allergic rhinitis or asthma

Chinese Journal of Contemporary Pediatrics

Volumn 16, Issue 12, 2014, Pages 1206-1210

  Ding, Lian Fu ^a   Chen, Qiang ^a   Li, Lan ^a   Liu, Jian Mei ^a   Zhang, Gao Ping ^a   Zhu, Xiao Hua ^a   Wu, Ai Min ^a   Ke, Jiang Wei ^a   Dai, Yu Lan ^a   Wu, Chun Xue ^a  

^a Children's Hospital of Jiangxi Province   (China)

Author keywords

Asthma; Child; Interleukin 17; Interleukin 35; Rhinitis; Sublingual immunotherapy

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 35; INTERLEUKIN DERIVATIVE; INTERLEUKIN-35, HUMAN;

AIRWAY RESISTANCE; ALLERGIC RHINITIS; ARTICLE; ASTHMA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DERMATOPHAGOIDES FARINAE; EOSINOPHIL; FORCED EXPIRATORY VOLUME; HUMAN; PROTEIN BLOOD LEVEL; SUBLINGUAL IMMUNOTHERAPY; TREATMENT OUTCOME; ADOLESCENT; BLOOD; FEMALE; MALE; PRESCHOOL CHILD; RHINITIS, ALLERGIC;

ADOLESCENT; ASTHMA; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INTERLEUKIN-17; INTERLEUKINS; MALE; RHINITIS, ALLERGIC; SUBLINGUAL IMMUNOTHERAPY;

EID: 84921508705     PISSN: 10088830     EISSN: None     Source Type: Journal    
DOI: 10.7499/j.issn.1008-8830.2014.12.004     Document Type: Article

References (15)

1. Mizutani N, Goshima H, Nabe T, et al. Complement C3a-induced IL-17 plays a critical role in an IgE-mediated late-phase asthmatic response and airway hyperresponsiveness via neutrophilic inflammation in mice[J]. J Immunol, 2012, 188(11): 5694-5705.
2. Naundorf S, Schroder M, Hoflich C, et al. IL-10 interferes directly with TCR-induced IFN-gamma but not IL-17 production in memory T cells[J]. Eur J Immunol, 2009, 39(4): 1066-1077.
3. Whitehead GS, Wilson RH, Nakano K, et al. IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease[J]. J Allergy Clin Immunol, 2012, 129(1): 207-215.
4. Fogli LK, Sundrud MS, Goel S, et al. T cell-derived IL-17 mediates epithelial changes in the airway and drives pulmonary neutrophilia[J]. J Immunol, 2013, 191(6): 3100-3111.
5. Dias PM, Banerjee G. The role of Th17/IL-17 on eosinophilic inflammation[J]. J Autoimmun, 2013, 40: 9-20.
6. Oboki K, Ohno T, Saito H, et al. Th17 and allergy[J]. Allergol Intern, 2008, 57(2):121-134.
7. Ciprandi G, De Amici M, Murdaca G, et al. Serum interleukin-17 levels are related to clinical severity in allergic rhinitis[J]. Allergy, 2009, 64(9): 1375-1378.
8. Olson BM, Sullivan JA, Burlingham WJ. Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance[J]. Front Immunol, 2013, 4: 315.
9. Lee S, Hwang HJ, Kim Y. Modeling the role of TGF-β in regulation of the Th17 phenotype in the LPS-driven immune system[J]. Bull Math Biol, 2014, 76(5): 1045-1080.
10. Collison LW, Workman CJ, Kuo TT, et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function[J]. Nature, 2007, 450(7169): 566-569.
11. Liu JQ, Liu Z, Zhang X, et al. Increased Th17 and regulatory T cell responses in EBV-induced gene 3-deficient mice lead to marginally enhanced development of autoimmune encephalomyelitis[J]. J Immunol, 2012, 188(7): 3099-3106.
12. Kochetkova I, Golden S, Holderness K, et al. IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10[J]. J Immunol, 2010, 184(12): 7144-7153.
13. Huang CH, Loo EX, Kuo IC, et al. Airway inflammation and IgE production induced by dust mite allergen-specific memory/ effector Th2 cell line can be effectively attenuated by IL-35[J]. J Immunol, 2011,187(1): 462-471.
14. Incorvaia C, Masieri S, Scurati S, et al. The current role of sublingual immunotherapy in the treatment of allergic rhinitis in adults and children[J]. J Asthma Allergy, 2011, 4: 13-17.
15. Canonica GW, Bousquet J, Casale T, et al. Sub-lingual immunotherapy: World Allergy Organization Position Paper 2009[J]. Allergy, 2009, 64 Suppl 91: 1-59.