A case-control study assessing bone mineral density in severe haemophilia A in the UK

Haemophilia

Volumn 21, Issue 1, 2015, Pages 109-115

  Wells, A J ^a,b   Mclaughlin, P ^c   Simmonds, J V ^d   Prouse, P J ^a   Prelevic, G ^c   Gill, S ^c   Chowdary, P ^c  

^a BASINGSTOKE AND NORTH HAMPSHIRE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^c ROYAL FREE HOSPITAL   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Bone mineral density; Haemophilia; Osteoporosis; Vitamin D

Indexed keywords

VITAMIN D;

ADULT; ARTICLE; BONE DENSITY; BONE MASS; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ETHNICITY; HEMOPHILIA A; HEPATITIS C; HUMAN; HYPOTHESIS; OSTEOPENIA; OSTEOPOROSIS; PRIORITY JOURNAL; QUESTIONNAIRE; UNITED KINGDOM; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; RISK FACTOR; YOUNG ADULT;

ADULT; BONE DENSITY; CASE-CONTROL STUDIES; GREAT BRITAIN; HEMOPHILIA A; HUMANS; MALE; MIDDLE AGED; OSTEOPOROSIS; RISK FACTORS; YOUNG ADULT;

EID: 84921503383     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/hae.12565     Document Type: Article

References (37)

1. Iorio A, Fabbriciani G, Marcucci M, Brozzetti M, Filipponi P. Bone mineral density in haemophilia patients: a meta-analysis. Thromb Haemost 2010; 103: 596-603.
2. Stephensen D. Biomechanics of the lower limb in haemophilia. In: Buzzard B, Beeton K eds. Physiotherapy Management of Haemophilia. Oxford: Blackwell Science Ltd, 2000: 77-87.
3. Jansen NW, Roosendaal G, Bijlsma JW, Degroot J, Lafeber FP. Exposure of human cartilage tissue to low concentrations of blood for a short period of time leads to prolonged cartilage damage: an in vitro study. Arthritis Rheum 2007; 56: 199-207.
4. Beeton K. Evaluation of outcome of care in patients with haemophilia. Haemophilia 2002; 8: 428-34.
5. Van Genderen FR, Van Meeteren NLU, Van der Bom JG et al. Functional consequences of haemophilia in adults: the development of the haemophilia activities list. Haemophilia 2004; 10: 565-71.
6. Kovacs CS. Haemophilia, low bone mass, and osteopenia/osteoporosis. Transfus Apheres Sci 2008; 38: 33-40.
7. Lewiecki EM, Watts NB, McClung MR et al. Official positions of the International Society for Clinical Densitometry. J Clin Endocrinol Metab 2004; 89: 3651-5.
8. Gurevitch O, Slavin S. The haematological etiology of osteoporosis. Med Hypotheses 2006; 67: 729-35.
9. Kaufman JM, Reginster JY, Boonen S et al. Treatment of osteoprosis in men. Bone 2013; 53: 134-44.
10. Brennan SL, Henry MJ, Wluka AE, Nicholson GC, Kotowicz MA, Pasco JA. Socioeconomic status and bone mineral density in a population-based sample of men. Bone 2010; 46: 993-9.
11. Gerstner G, Damiano ML, Tom A et al. Prevalence and risk factors associated with decreased bone mineral density in patients with haemophilia. Haemophilia 2009; 15: 559-65.
12. Katsarou O, Terpos E, Chatzismalis P et al. Increased bone resorption is implicated in the pathogenesis of bone loss in hemophiliacs: correlations with hemophilic arthropathy and HIV infection. Ann Hematol 2010; 89: 67-74.
13. Wallny TA, Scholz DT, Oldenburg J et al. Osteoporosis in haemophilia - an underestimated comorbidity? Haemophilia 2007; 13: 79-84.
14. Anagnostis P, Vakalopoulou S, Slavakis A et al. Reduced bone mineral density in patients with haemophilia A and B in Northern Greece. Thromb Haemost 2012; 107: 545-51.
15. Watts NB, Adler RA, Bilezikian JP et al. Osteoporosis in men: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2012; 97: 1802-22.
16. Binkley N. A perspective on male osteoporosis. Best Pract Res Clin Rheumatol 2009; 23: 755-68.
17. Hilliard P, Funk S, Zourikian N et al. Haemophilia joint health score reliability study. Haemophilia 2006; 12: 518-25.
18. Van Genderen FR, Westers P, Heijnen L et al. Measuring patients' perceptions on their functional abilities: validation of the Haemophilia Activities List. Haemophilia 2006; 12: 36-46.
19. Holick MF, Binkley NC, Bischoff-Ferrari HA et al. Evaluation, treatment, and prevention of vitamin D deficiency: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2011; 96: 1911-30.
20. Gallacher SJ, Deighan C, Wallace AM et al. Association of severe haemophilia A with osteoporosis: a densitometric and biochemical study. Q J Med 1994; 87: 181-6.
21. Nair AP, Jijina F, Ghosh K, Madkaikar M, Shrikhande M, Nema M. Osteoporosis in young haemophiliacs from Western India. Am J Hematol 2007; 82: 453-7.
22. Anagnostis P, Vakalopoulou S, Vyzantiadis TA et al. The clinical utility of bone turnover markers in the evaluation of bone disease in patients with haemophilia A and B. Haemophilia 2014; 20: 268-75.
23. Adler RA. Osteoporosis in men: insights for the clinician. Ther Adv Musculoskelet Dis 2011; 3: 191-200.
24. Khawaji M, Akesson K, Berntorp E. Long term prophylaxis in severe haemophilia seems to preserve bone mineral density. Haemophilia 2009; 15: 261-6.
25. Khawaji M, Astermark J, Akesson K, Berntorp E. Physical activity for prevention of osteoporosis in patients with severe haemophilia on long term prophylaxis. Haemophilia 2010; 16: 495-501.
26. Khawaji M, Astermark J, Von Mackensen S, Akesson K, Berntorp E. Bone density and health-related quality of life in adult patients with severe haemophilia. Haemophilia 2011; 17: 304-11.
27. Mansouritorghabeh H, Rezaieyazdi Z, Badiei Z. Are individuals with severe haemophilia A prone to reduced bone density? Rheumatol Int 2008; 28: 1079-83.
28. Holick MF. Vitamin D deficiency. New Eng J Med 2007; 357: 266-81.
29. Arlet JB, Courbebaisse M, Chatellier G et al. Relationship between vitamin D deficiency and bone fragility in sickle cell disease: a cohort study of 56 adults. Bone 2013; 52: 206-11.
30. Christodoulou S, Goula T, Drosos G (2013). Vitamin D and bone disease. Biomed Res Int, vol. 2013, Article ID 396541, 6 pages, 2013. doi:10.1155/2013/396541.
31. Holick MF (2004). Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nut, 80(suppl.), 1678S-88S.
32. Steno B, Batorova A, Stenova E, Badidova J, Jankovicova D. Evaluation of bone mineral density and bone turnover in patients with haemophilia. Haemophilia 2010; 16: 100.
33. Rajic N, Icin T, Urosevic I, Savic I, Savic A. Increased bone metabolic turnover in patients with hemophilia. Haematologica 2010; 95: 70-1.
34. Tuck SP, Datta HK. Osteoporosis in the aging male: treatment options. Clin Interv Aging 2007; 2: 521-36.
35. Madeo B, Zirilli L, Caffagni G et al. The osteoporotic male: overlooked and undermanaged? Clin Interv Aging 2007; 2: 305-12.
36. Khosla S, Amin S, Orwoll E. Osteoporosis in men. Endocr Rev 2008; 29: 441-64.
37. Compston J, Bowring C, Cooper A et al. Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: national osteoporosis guideline group (NOGG) update 2013. Maturitas 2013; 75: 392-6.