Miniaturized Plate Readers for Low-Cost, High-Throughput Phenotypic Screening

Journal of Laboratory Automation

Volumn 20, Issue 1, 2015, Pages 51-55

  Jensen, Paul A ^a   Dougherty, Bonnie V ^a   Moutinho, Thomas J ^a,b   Papin, Jason A ^a  

^a University of Virginia   (United States)

^b Worcester Polytechnic Institute   (United States)

Author keywords

growth curve; multiwell plate assays; phenotypic screening; plate reader

Indexed keywords

COSTS; DENSITY (OPTICAL); DENSITY MEASUREMENT (OPTICAL);

BIOLOGICAL CONTAINMENT; FAST SAMPLING RATES; GROWTH CURVES; MULTIPLE DEVICES; PHENOTYPIC SCREENING; PLATE ASSAY; REMOTE MONITORING; WIRELESS COMMUNICATIONS;

ENVIRONMENTAL CHAMBERS;

ANALOG DIGITAL CONVERTER; ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; ESCHERICHIA COLI; GROWTH RATE; HIGH THROUGHPUT PHENOTYPIC SCREENING; HIGH THROUGHPUT SCREENING; INFORMATION PROCESSING; INFORMATION RETRIEVAL; LIGHT EMITTING DIODE; MICROPLATE READER; NONHUMAN; OPTICAL DENSITY; PHENOTYPE; PSEUDOMONAS AERUGINOSA; SPECTROPHOTOMETRY; VALIDATION PROCESS; CYTOLOGY; DEVICES; LABORATORY AUTOMATION; PROCEDURES;

AUTOMATION, LABORATORY; CYTOLOGICAL TECHNIQUES; HIGH-THROUGHPUT SCREENING ASSAYS; SPECTROPHOTOMETRY;

EID: 84921484723     PISSN: 22110682     EISSN: 22110690     Source Type: Journal    
DOI: 10.1177/2211068214555414     Document Type: Article

References (7)

1. Dalgaard P.,Ross T.,Kamperman L., et al.Estimation of Bacterial Growth Rates from Turbidimetric and Viable Count Data.Int. J. Food Microbiol. 1994;23 (3–4): 391-404
2. Imamovic L.,Sommer M. O. A.Use of Collateral Sensitivity Networks to Design Drug Cycling Protocols That Avoid Resistance Development.Sci. Transl. Med. 2013;5 (204): 204ra132
3. Fong S. S.,Palsson B. Ø.Metabolic Gene-Deletion Strains of Escherichia coli Evolve to Computationally Predicted Growth Phenotypes.Nat. Genet. 2004;36 (10): 1056-1058
4. Kim B.,Du J.,Eriksen D. T., et al.Combinatorial Design of a Highly Efficient Xylose-Utilizing Pathway in Saccharomyces cerevisiae for the Production of Cellulosic Biofuels.Appl. Envir. Microbiol. 2013;79 (3): 931-941
5. Toprak E.,Veres A.,Yildiz S., et al.Building a Morbidostat: An Automated Continuous-Culture Device for Studying Bacterial Drug Resistance under Dynamically Sustained Drug Inhibition.Nat. Protoc. 2013;8 (3): 555-567
6. Zwietering M. H.,Jongenburger I.,Rombouts F. M., et al.Modeling of the Bacterial Growth Curve.Appl. Envir. Microbiol. 1990;56 (6): 1875-1881
7. Palmer K. L.,Aye L. M.,Whiteley M.Nutritional Cues Control Pseudomonas aeruginosa Multicellular Behavior in Cystic Fibrosis Sputum.J. Bacteriol. 2007;189 (22): 8079-8087