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Volumn 17, Issue 2, 2015, Pages

Giant Cell Arteritis and Polymyalgia Rheumatica: an Update

Author keywords

Aortitis; FDG PET; Giant cell arteritis; Polymyalgia rheumatica; Treatment

Indexed keywords

ADALIMUMAB; CORTICOSTEROID; FLUORODEOXYGLUCOSE F 18; INFLIXIMAB; METHOTREXATE; METHYLPREDNISOLONE; PREDNISONE; TOCILIZUMAB; GLUCOCORTICOID;

EID: 84921475237     PISSN: 15233774     EISSN: 15346307     Source Type: Journal    
DOI: 10.1007/s11926-014-0480-1     Document Type: Review
Times cited : (57)

References (50)
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    • NKG2D stimulated T-cell autoreactivity in giant cell arteritis and polymyalgia rheumatica
    • COI: 1:CAS:528:DC%2BC3sXhslymsb3P, PID: 23417963, This study highlights the relevance of T cells and the implication of NKG2D in the pathogenesis of GCA and PMR
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    • Th1 and Th17 lymphocytes expressing CD161 are implicated in giant cell arteritis and polymyalgia rheumatica pathogenesis
    • COI: 1:CAS:528:DC%2BC38Xhs1ShtrzI, PID: 22833233, Although the suppressive activity of circulating Treg cells is not altered, the number of circulating Treg cells is decreased in patients with GCA or PMR. The numbers of Th17 lymphocytes are significantly increased in patients with GCA and PMR
    • Samson M, Audia S, Fraszczak J, Trad M, Ornetti P, Lakomy D, et al. Th1 and Th17 lymphocytes expressing CD161 are implicated in giant cell arteritis and polymyalgia rheumatica pathogenesis. Arthritis Rheum. 2012;64:3788–98. Although the suppressive activity of circulating Treg cells is not altered, the number of circulating Treg cells is decreased in patients with GCA or PMR. The numbers of Th17 lymphocytes are significantly increased in patients with GCA and PMR.
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    • Arida, A.1    Kyprianou, M.2    Kanakis, M.3    Sfikakis, P.P.4
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    • Germanò G, Muratore F, Cimino L, Lo Gullo A, Possemato N, Macchioni P, et al. Is colour duplex sonography-guided temporal artery biopsy useful in the diagnosis of giant cell arteritis? A randomized study. Rheumatology (Oxford) 2014 Jun 17. pii: keu241. [Epub ahead of print] Interesting study that indicates that color duplex US of the temporal artery does not improve the sensitive of TAB to make a diagnosis of GCA. The results, rather than reducing the potential usefulness of color duplex US for the diagnosis of GCA, highlight the relevance of an adequate clinical examination to proceed to TAB when GCA is suspected
    • Germanò G, Muratore F, Cimino L, Lo Gullo A, Possemato N, Macchioni P, et al. Is colour duplex sonography-guided temporal artery biopsy useful in the diagnosis of giant cell arteritis? A randomized study. Rheumatology (Oxford) 2014 Jun 17. pii: keu241. [Epub ahead of print] Interesting study that indicates that color duplex US of the temporal artery does not improve the sensitive of TAB to make a diagnosis of GCA. The results, rather than reducing the potential usefulness of color duplex US for the diagnosis of GCA, highlight the relevance of an adequate clinical examination to proceed to TAB when GCA is suspected.
  • 18
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    • Biopsy-negative giant cell arteritis: clinical spectrum and predictive factors for positive temporal artery biopsy
    • COI: 1:STN:280:DC%2BD3M3hsVKqtA%3D%3D, PID: 11182025
    • Gonzalez-Gay MA, Garcia-Porrua C, Llorca J, Gonzalez-Louzao C, Rodriguez-Ledo P. Biopsy-negative giant cell arteritis: clinical spectrum and predictive factors for positive temporal artery biopsy. Semin Arthritis Rheum. 2001;30:249–56.
    • (2001) Semin Arthritis Rheum , vol.30 , pp. 249-256
    • Gonzalez-Gay, M.A.1    Garcia-Porrua, C.2    Llorca, J.3    Gonzalez-Louzao, C.4    Rodriguez-Ledo, P.5
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    • 84908556083 scopus 로고    scopus 로고
    • Inflamed temporal artery: histologic findings in 354 biopsies, with clinical correlations
    • PID: 25216320, Study on 322 temporal artery biopsies. It discloses the wide spectrum of inflammatory lesions found in TAB. It also confirmed that some conditions, in particular systemic vasculitides different from GCA, may cause inflammation of the temporal artery
    • Cavazza A, Muratore F, Boiardi L, Restuccia G, Pipitone N, Pazzola G, et al. Inflamed temporal artery: histologic findings in 354 biopsies, with clinical correlations. Am J Surg Pathol. 2014;38:1360–70. Study on 322 temporal artery biopsies. It discloses the wide spectrum of inflammatory lesions found in TAB. It also confirmed that some conditions, in particular systemic vasculitides different from GCA, may cause inflammation of the temporal artery.
    • (2014) Am J Surg Pathol , vol.38 , pp. 1360-1370
    • Cavazza, A.1    Muratore, F.2    Boiardi, L.3    Restuccia, G.4    Pipitone, N.5    Pazzola, G.6
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    • Sakellariou G, Iagnocco A, Riente L, Ceccarelli F, Carli L, Di Geso L, et al. Ultrasound imaging for the rheumatologist XLIII. Ultrasonographic evaluation of shoulders and hips in patients with polymyalgia rheumatica: a systematic literature review. Clin Exp Rheumatol. 2013;31:1–7. Very elegant review article that indicates that in patients with suggestive clinical features of PMR, a shoulder US, in particular when findings are bilateral, is useful to support a diagnosis of PMR.
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    • Role of imaging studies in the diagnosis and follow-up of large-vessel vasculitis: an update
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    • Puppo C, Massollo M, Paparo F, Camellino D, Piccardo A, Shoushtari Zadeh Naseri M, et al. Giant cell arteritis: a systematic review of the qualitative and semiquantitative methods to assess vasculitis with 18F-fluorodeoxyglucose positron emission tomography. Biomed Res Int. 2014;2014:574248. 18 F-FDG- PET is an effective tool for the diagnosis, grading, and follow-up of patients affected by GCA involving the aorta and its proximal branches. In this exhaustive review the authors assessed the qualitative and quantitative methods used for the assessment of vasculitis by 18-FDG-PET. They concluded that the qualitative methods may be more specific than semiquantitative ones, but they have lower sensitivity
    • Puppo C, Massollo M, Paparo F, Camellino D, Piccardo A, Shoushtari Zadeh Naseri M, et al. Giant cell arteritis: a systematic review of the qualitative and semiquantitative methods to assess vasculitis with 18F-fluorodeoxyglucose positron emission tomography. Biomed Res Int. 2014;2014:574248. 18 F-FDG- PET is an effective tool for the diagnosis, grading, and follow-up of patients affected by GCA involving the aorta and its proximal branches. In this exhaustive review the authors assessed the qualitative and quantitative methods used for the assessment of vasculitis by 18-FDG-PET. They concluded that the qualitative methods may be more specific than semiquantitative ones, but they have lower sensitivity.
  • 25
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    • Pérez-Martín I, Martinez-Rodriguez I, Jimenez-Bonilla J
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    • (2012) Clin Exp Rheumatol , vol.30 , pp. S110-S113
    • Bejerano, C.1    Blanco, R.2    González-Vela, C.3
  • 26
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    • Refractory polymyalgia rheumatica as presenting manifestation of large-vessel vasculitis associated to sarcoidosis. Successful response to adalimumab
    • PID: 22410180
    • Bejerano C, Blanco R, González-Vela C, Agüero R, Carril JM, González-Gay MA. Refractory polymyalgia rheumatica as presenting manifestation of large-vessel vasculitis associated to sarcoidosis. Successful response to adalimumab. Clin Exp Rheumatol. 2012;30(1 Suppl 70):S94–7.
    • (2012) Clin Exp Rheumatol , vol.30 , pp. S94-S97
    • Bejerano, C.1    Blanco, R.2    González-Vela, C.3    Agüero, R.4    Carril, J.M.5    González-Gay, M.A.6
  • 27
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    • Martínez-Rodríguez I, Martínez-Amador N, Banzo I, Quirce R, Jiménez-Bonilla J, De Arcocha-Torres M, et al. Assessment of aortitis by semiquantitative analysis of 180-min (18)F-FDG PET/CT acquisition images. Eur J Nucl Med Mol Imaging. 2014;41(12):2319–24. Prospective study that included 43 consecutive patients assessed by semiquantitative analysis of PET-CT because of suspected large vessel vasculitis. The authors found that images acquired 180 min after 18 F-FDG injection and a target to background ratio index of 1.34 showed very high accuracy and are strongly recommended for the diagnosis of aortitis in the clinical setting
    • Martínez-Rodríguez I, Martínez-Amador N, Banzo I, Quirce R, Jiménez-Bonilla J, De Arcocha-Torres M, et al. Assessment of aortitis by semiquantitative analysis of 180-min (18)F-FDG PET/CT acquisition images. Eur J Nucl Med Mol Imaging. 2014;41(12):2319–24. Prospective study that included 43 consecutive patients assessed by semiquantitative analysis of PET-CT because of suspected large vessel vasculitis. The authors found that images acquired 180 min after 18 F-FDG injection and a target to background ratio index of 1.34 showed very high accuracy and are strongly recommended for the diagnosis of aortitis in the clinical setting.
  • 28
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    • Baerlecken NT, Linnemann A, Gross WL, Moosig F, Vazquez-Rodriguez TR, Gonzalez-Gay MA, et al. Association of ferritin autoantibodies with giant cell arteritis/polymyalgia rheumatica. Ann Rheum Dis. 2012;71:943–7. Ferritin autoantibodies may be useful as a diagnostic and activity marker of PMR and GCA
    • Baerlecken NT, Linnemann A, Gross WL, Moosig F, Vazquez-Rodriguez TR, Gonzalez-Gay MA, et al. Association of ferritin autoantibodies with giant cell arteritis/polymyalgia rheumatica. Ann Rheum Dis. 2012;71:943–7. Ferritin autoantibodies may be useful as a diagnostic and activity marker of PMR and GCA.
  • 29
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    • Epitope mapping of antibodies against ferritin heavy chain in giant cell arteritis and polymyalgia rheumatica
    • PID: 23682607, Potential diagnostic test for GCA and PMR can be improved by combining three human ferritin peptide antibodies
    • Große K, Schmidt RE, Witte T, Baerlecken NT. Epitope mapping of antibodies against ferritin heavy chain in giant cell arteritis and polymyalgia rheumatica. Scand J Rheumatol. 2013;42:215–9. Potential diagnostic test for GCA and PMR can be improved by combining three human ferritin peptide antibodies.
    • (2013) Scand J Rheumatol , vol.42 , pp. 215-219
    • Große, K.1    Schmidt, R.E.2    Witte, T.3    Baerlecken, N.T.4
  • 30
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    • Clinical practice. Giant-cell arteritis and polymyalgia rheumatica
    • PID: 24988557, Review article that discussed preexisting information on the pathophysiology, diagnosis, clinical features and treatment of GCA. This review also points out some areas of uncertainty in GCA and PMR
    • Weyand CM, Goronzy JJ. Clinical practice. Giant-cell arteritis and polymyalgia rheumatica. N Engl J Med. 2014;371:50–7. Review article that discussed preexisting information on the pathophysiology, diagnosis, clinical features and treatment of GCA. This review also points out some areas of uncertainty in GCA and PMR.
    • (2014) N Engl J Med , vol.371 , pp. 50-57
    • Weyand, C.M.1    Goronzy, J.J.2
  • 31
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    • Ocular involvement in giant cell arteritis
    • COI: 1:STN:280:DC%2BC3sfjslGnsg%3D%3D, PID: 23663687, Cohort study that confirms the high frequency of visual manifestations in patients with GCA. Early recognition and rapid onset of corticosteroid therapy is of main importance to prevent irreversible visual loss
    • Figus M, Talarico R, Posarelli C, d’Ascanio A, Elefante E, Bombardieri S. Ocular involvement in giant cell arteritis. Clin Exp Rheumatol. 2013;31(1 Suppl 75):S96. Cohort study that confirms the high frequency of visual manifestations in patients with GCA. Early recognition and rapid onset of corticosteroid therapy is of main importance to prevent irreversible visual loss.
    • (2013) Clin Exp Rheumatol , vol.31 , pp. S96
    • Figus, M.1    Talarico, R.2    Posarelli, C.3    d’Ascanio, A.4    Elefante, E.5    Bombardieri, S.6
  • 32
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    • Permanent visual loss and cerebrovascular accidents in giant cell arteritis: predictors and response to treatment
    • Martínez-Taboada VM, Delgado-Rodriguez M, Figueroa
    • Gonzalez-Gay MA, Blanco R, Rodriguez-Valverde V, Martínez-Taboada VM, Delgado-Rodriguez M, Figueroa M, et al. Permanent visual loss and cerebrovascular accidents in giant cell arteritis: predictors and response to treatment. Arthritis Rheum. 1998;41:1497–504.
    • (1998) Arthritis Rheum , vol.41 , pp. 1497-1504
    • Gonzalez-Gay, M.A.1    Blanco, R.2    Rodriguez-Valverde, V.3
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    • Large-vessel involvement in giant cell arteritis and polymyalgia rheumatica
    • PID: 24854380, An extremely interesting and informative review article that highlights important points on the diagnosis and management of patients with large vessel involvement in the setting of GCA
    • Muratore F, Pazzola G, Pipitone N, Boiardi L, Salvarani C. Large-vessel involvement in giant cell arteritis and polymyalgia rheumatica. Clin Exp Rheumatol. 2014;32(3 Suppl 82):S106–S11. An extremely interesting and informative review article that highlights important points on the diagnosis and management of patients with large vessel involvement in the setting of GCA.
    • (2014) Clin Exp Rheumatol , vol.32 , pp. S106-S111
    • Muratore, F.1    Pazzola, G.2    Pipitone, N.3    Boiardi, L.4    Salvarani, C.5
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    • Muratore F, Kermani TA, Crowson CS, Green AB, Salvarani C, Matteson EL, et al. Large-vessel giant cell arteritis: a cohort study. Rheumatology (Oxford). 2014 Sep 5. pii: keu329. [Epub ahead of print] The clinical spectrum of patients with large vessel involvement in the setting of GCA is different from that found in patients presenting with typical cranial manifestations of GCA. Patients with large vessel involvement have less frequency of severe visual complication but they experience more relapses and have higher corticosteroid requirements than those presenting with classic cranial manifestations
    • Muratore F, Kermani TA, Crowson CS, Green AB, Salvarani C, Matteson EL, et al. Large-vessel giant cell arteritis: a cohort study. Rheumatology (Oxford). 2014 Sep 5. pii: keu329. [Epub ahead of print] The clinical spectrum of patients with large vessel involvement in the setting of GCA is different from that found in patients presenting with typical cranial manifestations of GCA. Patients with large vessel involvement have less frequency of severe visual complication but they experience more relapses and have higher corticosteroid requirements than those presenting with classic cranial manifestations.
  • 35
    • 84901913661 scopus 로고    scopus 로고
    • Talarico R, Boiardi L, Pipitone N, d'Ascanio A, Stagnaro C, Ferrari C, et al. Isolated aortitis versus giant cell arteritis: are they really two sides of the same coin? Clin Exp Rheumatol. 2014;32(3 Suppl 82):S55–8. An interesting study that confirms that the clinical spectrum of patients with isolated aortitis is different from that observed in those with cranial manifestations of GCA
    • Talarico R, Boiardi L, Pipitone N, d'Ascanio A, Stagnaro C, Ferrari C, et al. Isolated aortitis versus giant cell arteritis: are they really two sides of the same coin? Clin Exp Rheumatol. 2014;32(3 Suppl 82):S55–8. An interesting study that confirms that the clinical spectrum of patients with isolated aortitis is different from that observed in those with cranial manifestations of GCA.
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    • Ungprasert P, Sanguankeo A, Upala S, Knight EL. Risk of malignancy in patients with giant cell arteritis and polymyalgia rheumatica: A systematic review and meta-analysis. Semin Arthritis Rheum 2014 Jun 26. doi: 10.1016/j.semarthrit.2014.06.004. Overall, the risk of malignancy in GCA and PMR is not higher than in the general population.
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    • Tomasson G, Peloquin C, Mohammad A, Love TJ, Zhang Y, Choi HK, et al. Risk for cardiovascular disease early and late after a diagnosis of giant-cell arteritis: a cohort study. Ann Intern Med. 2014;160:73–80. Unlike previous studies, a recent report suggests that cardiovascular disease may be increased in GCA.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.