Higher rate of hepatitis events in patients with human immunodeficiency virus, hepatitis B, and hepatitis D genotype II infection: A cohort study in a medical center in southern Taiwan

Journal of Microbiology, Immunology and Infection

Volumn 48, Issue 1, 2015, Pages 20-27

  Lee, Chun Yuan ^a   Tsai, Hung Chin ^a,b   Lee, Susan Shin Jung ^a,b   Wu, Kuan Sheng ^a,b   Sy, Cheng Len ^a,b   Chen, Jui Kuang ^a,b   Chen, Yao Shen ^a,b,c  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL KAOHSIUNG NORMAL UNIVERSITY   (Taiwan)

Author keywords

Hepatitis B; Hepatitis virus; Human immunodeficiency virus

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; HEPATITIS B(E) ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; ANTIRETROVIRUS AGENT; HEPATITIS ANTIBODY;

ADULT; ARTICLE; CD4 LYMPHOCYTE COUNT; COHORT ANALYSIS; DELTA AGENT HEPATITIS; FEMALE; FOLLOW UP; GENOTYPE; HEPATITIS B; HETEROSEXUALITY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION; LABORATORY TEST; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MEN WHO HAVE SEX WITH MEN; MIXED INFECTION; MORTALITY; MULTIPLE MYELOMA; OUTCOME ASSESSMENT; PHYLOGENETIC TREE; PHYLOGENY; PROSPECTIVE STUDY; RISK FACTOR; SEROLOGY; SEROPREVALENCE; SUPERINFECTION; TAIWAN; VIREMIA; VIRUS LOAD; BLOOD; CLASSIFICATION; COINFECTION; COMPLICATION; GENETICS; HEPATITIS D; HEPATITIS DELTA VIRUS; HIV INFECTIONS; MIDDLE AGED; PATHOLOGY; TREATMENT OUTCOME; UNIVERSITY HOSPITAL; VIROLOGY; YOUNG ADULT;

ACADEMIC MEDICAL CENTERS; ADULT; ANTI-RETROVIRAL AGENTS; COHORT STUDIES; COINFECTION; FEMALE; GENOTYPE; HEPATITIS ANTIBODIES; HEPATITIS B; HEPATITIS D; HEPATITIS DELTA VIRUS; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; TAIWAN; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84921387637     PISSN: 16841182     EISSN: 19959133     Source Type: Journal    
DOI: 10.1016/j.jmii.2013.08.001     Document Type: Article

References (24)

1. Weber R., Sabin C.A., Friis-Møller N., Reiss P., El-Sadr W.M., Kirk O., et al. Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study. Arch Intern Med 2006, 166:1632-1641.
2. Novick D.M., Farci P., Croxson T.S., Taylor M.B., Schneebaum C.W., Lai M.E., et al. Hepatitis D virus and human immunodeficiency virus antibodies in parenteral drug abusers who are hepatitis B surface antigen positive. J Infect Dis 1988, 158:795-803.
3. Sheng W.H., Hung C.C., Kao J.H., Chang S.Y., Chen M.Y., Hsieh S.M., et al. Impact of hepatitis D virus infection on the long-term outcomes of patients with hepatitis B virus and HIV coinfection in the era of highly active antiretroviral therapy: a matched cohort study. Clin Infect Dis 2007, 44:988-995.
4. Soriano V., Grint D., d'Arminio Monforte A., Horban A., Leen C., Poveda E., et al. Hepatitis delta in HIV-infected individuals in Europe. AIDS 2011, 25:1987-1992.
5. Chen C.J., Wang L.Y., Yu M.W. Epidemiology of hepatitis B virus infection in the Asia-Pacific region. J Gastroenterol Hepatol 2000, 15(Suppl.):E3-E6.
6. Chen D.S., Lai M.Y., Sung J.L. Delta agent infection in patients with chronic liver diseases and hepatocellular carcinoma-an infrequent finding in Taiwan. Hepatology 1984, 4:502-503.
7. Chu F.Y., Chiang S.C., Su F.H., Chang Y.Y., Cheng S.H. Prevalence of human immunodeficiency virus and its association with hepatitis B, C, and D virus infections among incarcerated male substance abusers in Taiwan. J Med Virol 2009, 81:973-978.
8. Sheng W.H., Chen M.Y., Hsieh S.M., Hsiao C.F., Wang J.T., Hung C.C., et al. Impact of chronic hepatitis B virus (HBV) infection on outcomes of patients infected with HIV in an area where HBV infection is hyperendemic. Clin Infect Dis 2004, 38:1471-1477.
9. Chang S.Y., Yang C.L., Ko W.S., Liu W.C., Lin C.Y., Wu C.H., et al. Molecular epidemiology of hepatitis D virus infection among injecting drug users with and without human immunodeficiency virus infection in Taiwan. J Clin Microbiol 2011, 49:1083-1089.
10. Vincenti D., Solmone M., Garbuglia A.R., Iacomi F., Capobianchi M.R. A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations. J Virol Methods 2009, 159:53-57.
11. Pascarella S., Negro F. Hepatitis D virus: an update. Liver Int 2011, 31:7-21.
12. Ponzetto A., Hoyer B.H., Popper H., Engle R., Purcell R.H., Gerin J.L. Titration of the infectivity of hepatitis D virus in chimpanzees. J Infect Dis 1987, 155:72-78.
13. Kucirka L.M., Farzadegan H., Feld J.J., Mehta S.H., Winters M., Glenn J.S., et al. Prevalence, correlates, and viral dynamics of hepatitis delta among injection drug users. J Infect Dis 2010, 202:845-852.
14. Chung D.C., Ko Y.C., Chen C.J., Chen E.R., Wu C.C., Wu P.S. Seroepidemiology of hepatitis B virus, hepatitis D virus, and human immunodeficiency virus infections among parenteral drug abusers in southern Taiwan. J Med Virol 1989, 28:215-218.
15. Lee S.D., Wang J.Y., Wu J.C., Chiang Y.T., Tsai Y.T., Lo K.J. Hepatitis B and D virus infection among drug abusers in Taiwan. J Med Virol 1986, 20:247-252.
16. Chen P.J., Chen D.S., Chen C.R., Chen Y.Y., Chen H.M., Lai M.Y., et al. Delta infection in asymptomatic carriers of hepatitis B surface antigen: low prevalence of delta activity and effective suppression of hepatitis B virus replication. Hepatology 1988, 8:1121-1124.
17. Hsu H.M., Wang Y.F., Lo S.H., Sun H.C., Yip K.K., Chen J.S., et al. Hepatitis D virus infection among intravenous drug abusers in Taiwan: analysis of risk factors and liver function tests. J Med Virol 1990, 31:76-81.
18. Hughes S.A., Wedemeyer H., Harrison P.M. Hepatitis delta virus. Lancet 2011, 378:73-85.
19. Wu J.C., Choo K.B., Chen C.M., Chen T.Z., Huo T.I., Lee S.D. Genotyping of hepatitis D virus by restriction-fragment length polymorphism and relation to outcome of hepatitis D. Lancet 1995, 346:939-941.
20. Su C.W., Huang Y.H., Huo T.I., Shih H.H., Sheen I.J., Chen S.W., et al. Genotypes and viremia of hepatitis B and D viruses are associated with outcomes of chronic hepatitis D patients. Gastroenterology 2006, 130:1625-1635.
21. Smedile A., Farci P., Verme G., Caredda F., Cargnel A., Caporaso N., et al. Influence of delta infection on severity of hepatitis B. Lancet 1982, 2:945-947.
22. Kao J.H., Chen P.J., Lai M.Y., Chen D.S. Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 2000, 118:554-559.
23. Sheng W.H., Hung C.C., Chang S.Y., Liu C.J., Chen M.Y., Hsieh S.M., et al. Differential clinical and virologic impact of hepatitis B virus genotypes B and C on HIV-coinfected patients receiving lamivudine-containing highly active antiretroviral therapy. Clin Infect Dis 2012, 54:548-555.
24. Schaper M., Rodriguez-Frias F., Jardi R., Tabernero D., Homs M., Ruiz G., et al. Quantitative longitudinal evaluations of hepatitis delta virus RNA and hepatitis B virus DNA shows a dynamic, complex replicative profile in chronic hepatitis B and D. J Hepatol 2010, 52:658-664.