메뉴 건너뛰기




Volumn 10, Issue 4, 2014, Pages 853-858

An overview of doxorubicin formulations in cancer therapy

Author keywords

Liposomal; nonpegylated; nudoxa; pegylated

Indexed keywords

DOXORUBICIN; LIPOSOME; MACROGOL; ANTINEOPLASTIC ANTIBIOTIC; MACROGOL DERIVATIVE;

EID: 84921385610     PISSN: 09731482     EISSN: 19984138     Source Type: Journal    
DOI: 10.4103/0973-1482.139267     Document Type: Review
Times cited : (544)

References (42)
  • 1
    • 84921404593 scopus 로고    scopus 로고
    • GLOBOCAN (IARC) Section of Cancer Information. Available from [Last accessed on 2012 May 10]
    • GLOBOCAN (IARC) Section of Cancer Information. Available from: http://www.globocan.iarc.fr/factsheets/populations/factsheet.aspuno=900. [Last accessed on 2012 May 10].
  • 2
    • 13244281955 scopus 로고    scopus 로고
    • Innovations in anthracycline therapy: Overview
    • Thigpen JT. Innovations in anthracycline therapy: Overview. Commun Oncol 2005;2:3-7.
    • (2005) Commun Oncol , vol.2 , pp. 3-7
    • Thigpen, J.T.1
  • 3
    • 2342488025 scopus 로고    scopus 로고
    • Cardiac profiles of liposomal anthracyclines: Greater cardiac safety versus conventional doxorubicin
    • Theodoulou M, Hudis C. Cardiac profiles of liposomal anthracyclines: Greater cardiac safety versus conventional doxorubicin Cancer 2004;100:2052-63.
    • (2004) Cancer , vol.100 , pp. 2052-2063
    • Theodoulou, M.1    Hudis, C.2
  • 4
    • 84856452267 scopus 로고    scopus 로고
    • Liposomal drug formulations in cancer therapy: 15 years along the road
    • Slingerland M, Guchelaar HJ, Gelderblom H. Liposomal drug formulations in cancer therapy: 15 years along the road. Drug Discov Today 2012;17:160-6.
    • (2012) Drug Discov Today , vol.17 , pp. 160-166
    • Slingerland, M.1    Guchelaar, H.J.2    Gelderblom, H.3
  • 5
    • 0000097143 scopus 로고
    • Anthracyclinones and anthracyclines. Rhodomycinone, pyrromycinone and their glycosides)
    • Brockmann H. Anthracyclinones and anthracyclines. (Rhodomycinone, pyrromycinone and their glycosides). Fortschr Chem Org Naturst 1963;21:121-82.
    • (1963) Fortschr Chem Org Naturst , vol.21 , pp. 121-182
    • Brockmann, H.1
  • 6
    • 0014603427 scopus 로고
    • Adriamycin, 14-hydroxydaunomycin, a new antitumor antibiotic from S peucetius var caesius
    • Arcamone F, Cassinelli G, Fantini G, Grein A, Orezzi P, Pol C, et al. Adriamycin, 14-hydroxydaunomycin, a new antitumor antibiotic from S. peucetius var. caesius. Biotechnol Bioeng 1969;11:1101-10.
    • (1969) Biotechnol Bioeng , vol.11 , pp. 1101-1110
    • Arcamone, F.1    Cassinelli, G.2    Fantini, G.3    Grein, A.4    Orezzi, P.5    Pol, C.6
  • 7
    • 84921404592 scopus 로고    scopus 로고
    • Available from [Last accessed on 2014 Apr 28]
    • Available from: http://www.usbio.net/misc/doxorubicin. [Last accessed on 2014 Apr 28].
  • 9
    • 0017178490 scopus 로고
    • Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells
    • Momparler RL, Karon M, Siegel SE, Avila F. Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells. Cancer Res 1976;36:2891-5.
    • (1976) Cancer Res , vol.36 , pp. 2891-2895
    • Momparler, R.L.1    Karon, M.2    Siegel, S.E.3    Avila, F.4
  • 10
    • 84921404591 scopus 로고    scopus 로고
    • Available from [Last accessed on 2013 Oct 24]
    • Available from: http://www.cancer.gov/cancertopics/druginfo/fda-doxorubicin-HCL-liposome. [Last accessed on 2013 Oct 24].
  • 11
    • 0002997554 scopus 로고    scopus 로고
    • Basic principles of cancer treatment and cancer chemotherapy
    • In DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, editors Stamford, Conn: Appleton and Lange
    • Balmer C, Valley AW. Basic principles of cancer treatment and cancer chemotherapy. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, editors. Pharmacotherapy: A Pathophysiologic Approach. 3 rd ed. Stamford, Conn: Appleton and Lange; 1997. p. 2403-65.
    • (1997) Pharmacotherapy: A Pathophysiologic Approach. 3 Rd Ed , pp. 2403-2465
    • Balmer, C.1    Valley, A.W.2
  • 12
    • 0035164058 scopus 로고    scopus 로고
    • A comparison of liposomal formulations of doxorubicin with drug administered in free form: Changing toxicity profiles
    • Waterhouse DN, Tardi PG, Mayer LD, Bally MB. A comparison of liposomal formulations of doxorubicin with drug administered in free form: Changing toxicity profiles. Drug Saf 2001;24:903-20.
    • (2001) Drug Saf , vol.24 , pp. 903-920
    • Waterhouse, D.N.1    Tardi, P.G.2    Mayer, L.D.3    Bally, M.B.4
  • 13
    • 0034091608 scopus 로고    scopus 로고
    • Cardiotoxicity of chemotherapeutic agents: Incidence, treatment and prevention
    • Pai VB, Nahata MC. Cardiotoxicity of chemotherapeutic agents: Incidence, treatment and prevention. Drug Saf 2000;22:263-302.
    • (2000) Drug Saf , vol.22 , pp. 263-302
    • Pai, V.B.1    Nahata, M.C.2
  • 14
    • 0036229015 scopus 로고    scopus 로고
    • Anthracyclines in the treatment of gynecologic malignancies
    • Maluf FC, Spriggs D. Anthracyclines in the treatment of gynecologic malignancies. Gynecol Oncol 2002;85:18-31.
    • (2002) Gynecol Oncol , vol.85 , pp. 18-31
    • Maluf, F.C.1    Spriggs, D.2
  • 15
    • 0030713362 scopus 로고    scopus 로고
    • Anthracyclines in the treatment of cancer. An overview
    • Hortobágyi GN. Anthracyclines in the treatment of cancer. An overview. Drugs 1997;54:1-7.
    • (1997) Drugs , vol.54 , pp. 1-7
    • Hortobágyi, G.N.1
  • 17
    • 0038521374 scopus 로고    scopus 로고
    • Congestive heart failure in patients treated with doxorubicin: A retrospective analysis of three trials
    • Swain SM, Whaley FS, Ewer MS. Congestive heart failure in patients treated with doxorubicin: A retrospective analysis of three trials. Cancer 2003;97:2869-79.
    • (2003) Cancer , vol.97 , pp. 2869-2879
    • Swain, S.M.1    Whaley, F.S.2    Ewer, M.S.3
  • 18
    • 0034210816 scopus 로고    scopus 로고
    • Anthracyclines and cardiotoxicity
    • Birtle AJ. Anthracyclines and cardiotoxicity. Clin Oncol (R Coll Radiol) 2000;12:146-52.
    • (2000) Clin Oncol (R Coll Radiol) , vol.12 , pp. 146-152
    • Birtle, A.J.1
  • 19
    • 0033113566 scopus 로고    scopus 로고
    • Use of dexrazoxane as a cardioprotectant in patients receiving doxorubicin or epirubicin chemotherapy for the treatment of cancer.The Provincial Systemic Treatment Disease Site Group
    • Seymour L, Bramwell V, Moran LA. Use of dexrazoxane as a cardioprotectant in patients receiving doxorubicin or epirubicin chemotherapy for the treatment of cancer. The Provincial Systemic Treatment Disease Site Group. Cancer Prev Control 1999;3:145-59.
    • (1999) Cancer Prev Control , vol.3 , pp. 145-159
    • Seymour, L.1    Bramwell, V.2    Moran, L.A.3
  • 21
    • 29444449619 scopus 로고    scopus 로고
    • Pharmacokinetics (PK) of a liposomal encapsulated fraction containing doxorubicin and of doxorubicin released from the liposomal capsule after intravenous infusion of Caelyx/Doxil
    • Hilger RA, Richly H, Grubert M, Oberhoff C, Strumberg D, Scheulen ME, et al. Pharmacokinetics (PK) of a liposomal encapsulated fraction containing doxorubicin and of doxorubicin released from the liposomal capsule after intravenous infusion of Caelyx/Doxil. Int J Clin Pharmacol Ther 2005;43:588-9.
    • (2005) Int J Clin Pharmacol Ther , vol.43 , pp. 588-589
    • Hilger, R.A.1    Richly, H.2    Grubert, M.3    Oberhoff, C.4    Strumberg, D.5    Scheulen, M.E.6
  • 22
    • 0025816790 scopus 로고
    • Comparative pharmacokinetics of doxorubicin given by three different schedules with equal dose intensity in patients with breast cancer
    • Twelves CJ, Dobbs NA, Aldhous M, Harper PG, Rubens RD, Richards MA. Comparative pharmacokinetics of doxorubicin given by three different schedules with equal dose intensity in patients with breast cancer. Cancer Chemother Pharmacol 1991;28:302-7.
    • (1991) Cancer Chemother Pharmacol , vol.28 , pp. 302-307
    • Twelves, C.J.1    Dobbs, N.A.2    Aldhous, M.3    Harper, P.G.4    Rubens, R.D.5    Richards, M.A.6
  • 23
    • 0030669086 scopus 로고    scopus 로고
    • Polyethylene glycol-coated (pegylated) liposomal doxorubicin. Rationale for use in solid tumours
    • Gabizon A, Martin F. Polyethylene glycol-coated (pegylated) liposomal doxorubicin. Rationale for use in solid tumours. Drugs 1997;54 Suppl 4:15-21.
    • (1997) Drugs , vol.54 , pp. 15-21
    • Gabizon, A.1    Martin, F.2
  • 24
    • 0028349925 scopus 로고
    • Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes
    • Gabizon A, Catane R, Uziely B, Kaufman B, Safra T, Cohen R, et al. Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res 1994;54:987-92.
    • (1994) Cancer Res , vol.54 , pp. 987-992
    • Gabizon, A.1    Catane, R.2    Uziely, B.3    Kaufman, B.4    Safra, T.5    Cohen, R.6
  • 25
    • 84921404590 scopus 로고    scopus 로고
    • Available from [Last accessed 2012 May 14]
    • Available from: http://www.doxil.com/. [Last accessed 2012 May 14].
  • 26
    • 0032713936 scopus 로고    scopus 로고
    • Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: Is surface coating with polyethylene glycol beneficial
    • Hong RL, Huang CJ, Tseng YL, Pang VF, Chen ST, Liu JJ, et al. Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: Is surface coating with polyethylene glycol beneficial Clin Cancer Res 1999;5:3645-52.
    • (1999) Clin Cancer Res , vol.5 , pp. 3645-3652
    • Hong, R.L.1    Huang, C.J.2    Tseng, Y.L.3    Pang, V.F.4    Chen, S.T.5    Liu, J.J.6
  • 27
    • 0030973901 scopus 로고    scopus 로고
    • Accumulation of liposomal lipid and encapsulated doxorubicin in murine lewis lung carcinoma: The lack of beneficial effects by coating liposomes with poly (ethylene glycol)
    • Parr MJ, Masin D, Cullis PR, Bally MB. Accumulation of liposomal lipid and encapsulated doxorubicin in murine lewis lung carcinoma: The lack of beneficial effects by coating liposomes with poly (ethylene glycol). J Pharmacol Exp Ther 1997;280:1319-27.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 1319-1327
    • Parr, M.J.1    Masin, D.2    Cullis, P.R.3    Bally, M.B.4
  • 28
    • 0036096806 scopus 로고    scopus 로고
    • Liposome-based drug delivery in breast cancer treatment
    • Park JW. Liposome-based drug delivery in breast cancer treatment. Breast Cancer Res 2002;4:95-9.
    • (2002) Breast Cancer Res , vol.4 , pp. 95-99
    • Park, J.W.1
  • 29
    • 84921404589 scopus 로고    scopus 로고
    • Available from [Last accessed on 2012 May 14]
    • Available from: http://www.macmillan.org.uk/Cancerinformation/Cancertreatment/Treatmenttypes/Chemotherapy/Individualdrugs/Liposomaldoxorubicin.aspx. [Last accessed on 2012 May 14].
  • 31
    • 84921404588 scopus 로고    scopus 로고
    • Available from [Last accessed on 2013 Oct 24]
    • Available from: http://www.ema.europa.eu/docs/en-GB/document-library/EPAR-Scientific-Discussion/human/000297/WC500031808.pdf. [Last accessed on 2013 Oct 24].
  • 32
    • 34548482374 scopus 로고    scopus 로고
    • Stealth liposomes: Review of the basic science, rationale, and clinical applications, existing and potential
    • Immordino ML, Dosio F, Cattel L. Stealth liposomes: Review of the basic science, rationale, and clinical applications, existing and potential. Int J Nanomedicine 2006;1:297-315.
    • (2006) Int J Nanomedicine , vol.1 , pp. 297-315
    • Immordino, M.L.1    Dosio, F.2    Cattel, L.3
  • 33
    • 12344262085 scopus 로고    scopus 로고
    • Drug transport to brain with targeted liposomes
    • Schnyder A, Huwyler J. Drug transport to brain with targeted liposomes. NeuroR×2005;2:99-107.
    • (2005) NeuroR× , vol.2 , pp. 99-107
    • Schnyder, A.1    Huwyler, J.2
  • 34
    • 33749835513 scopus 로고    scopus 로고
    • Intracellular drug delivery by sulfatide-mediated liposomes to gliomas
    • Shao K, Hou Q, Duan W, Go ML, Wong KP, Li QT. Intracellular drug delivery by sulfatide-mediated liposomes to gliomas. J Control Release 2006;115:150-7.
    • (2006) J Control Release , vol.115 , pp. 150-157
    • Shao, K.1    Hou, Q.2    Duan, W.3    Go, M.L.4    Wong, K.P.5    Li, Q.T.6
  • 36
    • 0030271584 scopus 로고    scopus 로고
    • Sustained release of adriamycin from implanted hydroxyapatite blocks for the treatment of experimental osteogenic sarcoma in mice
    • Itokazu M, Kumazawa S, Wada E, Wenyi Y. Sustained release of adriamycin from implanted hydroxyapatite blocks for the treatment of experimental osteogenic sarcoma in mice. Cancer Lett 1996;107:11-8.
    • (1996) Cancer Lett , vol.107 , pp. 11-18
    • Itokazu, M.1    Kumazawa, S.2    Wada, E.3    Wenyi, Y.4
  • 37
    • 0037436029 scopus 로고    scopus 로고
    • Effects of polyether-modified poly (acrylic acid) microgels on doxorubicin transport in human intestinal epithelial Caco-2 cell layers
    • Bromberg L, Alakhov V. Effects of polyether-modified poly (acrylic acid) microgels on doxorubicin transport in human intestinal epithelial Caco-2 cell layers. J Control Release 2003;88:11-22.
    • (2003) J Control Release , vol.88 , pp. 11-22
    • Bromberg, L.1    Alakhov, V.2
  • 38
    • 0024556698 scopus 로고
    • Encapsulation of doxorubicin in liver-targeted erythrocytes increases the therapeutic index of the drug in a murine metastatic model
    • Zocchi E, Tonetti M, Polvani C, Guida L, Benatti U, De Flora A. Encapsulation of doxorubicin in liver-targeted erythrocytes increases the therapeutic index of the drug in a murine metastatic model. Proc Natl Acad Sci USA 1989;86:2040-4.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2040-2044
    • Zocchi, E.1    Tonetti, M.2    Polvani, C.3    Guida, L.4    Benatti, U.5    De Flora, A.6
  • 39
    • 12344307628 scopus 로고    scopus 로고
    • Drug transport to brain with targeted nanoparticles
    • Olivier JC. Drug transport to brain with targeted nanoparticles. NeuroRx 2005;2:108-19.
    • (2005) Neuro Rx , vol.2 , pp. 108-119
    • Olivier, J.C.1
  • 40
    • 33846499122 scopus 로고    scopus 로고
    • Chemotherapy of brain tumour using doxorubicin bound to surfactant-coated poly (butyl cyanoacrylate) nanoparticles: Revisiting the role of surfactants
    • Petri B, Bootz A, Khalansky A, Hekmatara T, Müller R, Uhl R, et al. Chemotherapy of brain tumour using doxorubicin bound to surfactant-coated poly (butyl cyanoacrylate) nanoparticles: Revisiting the role of surfactants. J Control Release 2007;117:51-8.
    • (2007) J Control Release , vol.117 , pp. 51-58
    • Petri, B.1    Bootz, A.2    Khalansky, A.3    Hekmatara, T.4    Müller, R.5    Uhl, R.6
  • 41
    • 33847284493 scopus 로고    scopus 로고
    • In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model
    • Wong HL, Rauth AM, Bendayan R, Wu XY. In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model. Eur J Pharm Biopharm 2007;65:300-8.
    • (2007) Eur J Pharm Biopharm , vol.65 , pp. 300-308
    • Wong, H.L.1    Rauth, A.M.2    Bendayan, R.3    Wu, X.Y.4
  • 42
    • 20444416355 scopus 로고    scopus 로고
    • Poly (d, l-lactide-co-glycolide)/montmorillonite nanoparticles for oral delivery of anticancer drugs
    • Dong Y, Feng SS. Poly (d, l-lactide-co-glycolide)/montmorillonite nanoparticles for oral delivery of anticancer drugs. Biomaterials 2005;26:6068-76.
    • (2005) Biomaterials , vol.26 , pp. 6068-6076
    • Dong, Y.1    Feng, S.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.