Retrospective evaluation of therapeutic drug monitoring of clozapine and norclozapine in Belgium using a multidrug UHPLC-MS/MS method

Clinical Biochemistry

Volumn 47, Issue 18, 2014, Pages 336-339

  Patteet, Lisbeth ^a,b   Maudens, Kristof E ^a   Vermeulen, Zarha ^a   Dockx, Greetje ^b   De Doncker, Mireille ^b   Morrens, Manuel ^c   Sabbe, Bernard ^c   Neels, Hugo ^a,b  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b Stuivenberg General Hospital   (Belgium)

^c UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Antipsychotic drugs; Clozapine; Therapeutic drug monitoring; UHPLC MS MS

Indexed keywords

AMISULPRIDE; ARIPIPRAZOLE; BROMPERIDOL; CLOZAPINE; DRUG METABOLITE; FLUVOXAMINE; HALOPERIDOL; NORCLOZAPINE; OLANZAPINE; PALIPERIDONE; PIPAMPERONE; QUETIAPINE; RISPERIDONE; ZUCLOPENTHIXOL; NEUROLEPTIC AGENT;

ADULT; AGED; ANALYTIC METHOD; ARTICLE; BELGIUM; BLOOD SAMPLING; CLINICAL EVALUATION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG METABOLISM; DRUG MONITORING; FEMALE; HUMAN; LIQUID LIQUID EXTRACTION; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; MORNING DOSAGE; PRACTICE GUIDELINE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TANDEM MASS SPECTROMETRY; TREATMENT DURATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANALOGS AND DERIVATIVES; BLOOD; EVALUATION STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MIDDLE AGED; PROCEDURES; REPRODUCIBILITY; YOUNG ADULT;

ADULT; AGED; ANTIPSYCHOTIC AGENTS; BELGIUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLOZAPINE; DRUG MONITORING; FEMALE; HUMANS; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; TANDEM MASS SPECTROMETRY; YOUNG ADULT;

EID: 84921374102     PISSN: 00099120     EISSN: 18732933     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2014.09.021     Document Type: Article

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