MicroRNA expression patterns in the malignant progression of gliomas and a 5-microRNA signature for prognosis

Oncotarget

Volumn 5, Issue 24, 2014, Pages 12908-12915

  Yan, Wei ^a,b   Li, Rui ^b   Liu, Yanwei ^a,d   Yang, Pei ^a,d   Wang, Zheng ^a,d   Zhang, Chuanbao ^a,d   Bao, Zhaoshi ^a,d   Zhang, Wei ^a,d   You, Yongping ^b   Jiang, Tao ^a,c,d  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

^d CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Anaplastic gliomas; MicroRNAs; MiR 105 767 cluster; Proneural glioblastomas; Secondary glioblastomas; TCGA

Indexed keywords

MICRORNA; MICRORNA 105; MICRORNA 16; MICRORNA 17; MICRORNA 181A; MICRORNA 196A; MICRORNA 20A; MICRORNA 296; MICRORNA 328; MICRORNA 584; MICRORNA 590; MICRORNA 767; MICRORNA LET 7A; MICRORNA LET 7B; MICRORNA LET 7C; MICRORNA LET 7D; MICRORNA LET 7F; MICRORNA LET 7I; UNCLASSIFIED DRUG;

ANAPLASTIC GLIOMA; ARTICLE; CANCER GRADING; CANCER GROWTH; CANCER LOCALIZATION; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GLIOBLASTOMA; GLIOMA; HIGH RISK POPULATION; HIGH THROUGHPUT SEQUENCING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LOW RISK POPULATION; MESENCHYMAL GLIOBLASTOMA; MICROARRAY ANALYSIS; NEURAL GLIOBLASTOMA; OVERALL SURVIVAL; PATIENT IDENTIFICATION; PREDICTIVE VALUE; PROGRESSION FREE SURVIVAL; PRONEURAL GLIOBLASTOMA; RISK ASSESSMENT; SECONDARY GLIOBLASTOMA; BIOSYNTHESIS; BRAIN TUMOR; COHORT ANALYSIS; DISEASE COURSE; GENETICS; METABOLISM; PATHOLOGY; PROGNOSIS;

BRAIN NEOPLASMS; COHORT STUDIES; DISEASE PROGRESSION; GLIOBLASTOMA; HUMANS; MICRORNAS; PROGNOSIS;

EID: 84921368284     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2679     Document Type: Article

References (21)

1. Schickel R, Boyerinas B, Park SM and Peter ME. MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death. Oncogene. 2008; 27(45):5959-5974.
2. Lee HK, Finniss S, Cazacu S, Bucris E, Ziv-Av A, Xiang C, Bobbitt K, Rempel SA, Hasselbach L, Mikkelsen T, Slavin S and Brodie C. Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal. Oncotarget. 2013; 4(2):346-361.
3. Calin GA and Croce CM. MicroRNAs and chromosomal abnormalities in cancer cells. Oncogene. 2006; 25(46):6202- 6210.
4. Asuthkar S, Velpula KK, Chetty C, Gorantla B and Rao JS. Epigenetic regulation of miRNA-211 by MMP-9 governs glioma cell apoptosis, chemosensitivity and radiosensitivity. Oncotarget. 2012; 3(11):1439-1454.
5. Wang D, Qiu C, Zhang H, Wang J, Cui Q and Yin Y. Human microRNA oncogenes and tumor suppressors show significantly different biological patterns: from functions to targets. PLoS One. 2010; 5(9).
6. Speranza MC, Frattini V, Pisati F, Kapetis D, Porrati P, Eoli M, Pellegatta S and Finocchiaro G. NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma. Oncotarget. 2012; 3(7):723-734.
7. Smits M, Nilsson J, Mir SE, van der Stoop PM, Hulleman E, Niers JM, de Witt Hamer PC, Marquez VE, Cloos J, Krichevsky AM, Noske DP, Tannous BA and Wurdinger T. miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis. Oncotarget. 2010; 1(8):710-720.
8. Li H and Yang BB. Stress response of glioblastoma cells mediated by miR-17-5p targeting PTEN and the passenger strand miR-17-3p targeting MDM2. Oncotarget. 2012; 3(12):1653-1668.
9. Wang L, Shi ZM, Jiang CF, Liu X, Chen QD, Qian X, Li DM, Ge X, Wang XF, Liu LZ, You YP, Liu N and Jiang BH. MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma. Oncotarget. 2014; 5(14):5416-5427.
10. Bier A, Giladi N, Kronfeld N, Lee HK, Cazacu S, Finniss S, Xiang C, Poisson L, deCarvalho AC, Slavin S, Jacoby E, Yalon M, Toren A, Mikkelsen T and Brodie C. MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1. Oncotarget. 2013; 4(5):665-676.
11. Malzkorn B, Wolter M, Liesenberg F, Grzendowski M, Stuhler K, Meyer HE and Reifenberger G. Identification and functional characterization of microRNAs involved in the malignant progression of gliomas. Brain Pathol. 2010; 20(3):539-550.
12. Yan W, Zhang W, You G, Zhang J, Han L, Bao Z, Wang Y, Liu Y, Jiang C, Kang C, You Y and Jiang T. Molecular classification of gliomas based on whole genome gene expression: a systematic report of 225 samples from the Chinese Glioma Cooperative Group. Neuro Oncol. 2012; 14(12):1432-1440.
13. Dave SS, Wright G, Tan B, Rosenwald A, Gascoyne RD, Chan WC, Fisher RI, Braziel RM, Rimsza LM, Grogan TM, Miller TP, LeBlanc M, Greiner TC, Weisenburger DD, Lynch JC, Vose J, et al. Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. N Engl J Med. 2004; 351(21):2159-2169.
14. Zhao Q and Sun J. Cox survival analysis of microarray gene expression data using correlation principal component regression. Stat Appl Genet Mol Biol. 2007; 6:Article16.
15. Srinivasan S, Patric IR and Somasundaram K. A tenmicroRNA expression signature predicts survival in glioblastoma. PLoS One. 2011; 6(3):e17438.
16. Godlewski J, Nowicki MO, Bronisz A, Williams S, Otsuki A, Nuovo G, Raychaudhury A, Newton HB, Chiocca EA and Lawler S. Targeting of the Bmi-1 oncogene/ stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res. 2008; 68(22):9125-9130.
17. Shi L, Cheng Z, Zhang J, Li R, Zhao P, Fu Z and You Y. hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells. Brain Res. 2008; 1236:185-193.
18. DeAngelis LM. Anaplastic glioma: how to prognosticate outcome and choose a treatment strategy. [corrected]. J Clin Oncol. 2009; 27(35):5861-5862.
19. Tan X, Qin W, Zhang L, Hang J, Li B, Zhang C, Wan J, Zhou F, Shao K, Sun Y, Wu J, Zhang X, Qiu B, Li N, Shi S, Feng X, et al. A 5-microRNA signature for lung squamous cell carcinoma diagnosis and hsa-miR-31 for prognosis. Clin Cancer Res. 2011; 17(21):6802-6811.
20. Schaefer A, Jung M, Mollenkopf HJ, Wagner I, Stephan C, Jentzmik F, Miller K, Lein M, Kristiansen G and Jung K. Diagnostic and prognostic implications of microRNA profiling in prostate carcinoma. Int J Cancer. 2010; 126(5):1166-1176.
21. Guan Y, Mizoguchi M, Yoshimoto K, Hata N, Shono T, Suzuki SO, Araki Y, Kuga D, Nakamizo A, Amano T, Ma X, Hayashi K and Sasaki T. MiRNA-196 is upregulated in glioblastoma but not in anaplastic astrocytoma and has prognostic significance. Clin Cancer Res. 2010; 16(16):4289-4297.