Familial aggregation of gout and relative genetic and environmental contributions: A nationwide population study in Taiwan

Annals of the Rheumatic Diseases

Volumn 74, Issue 2, 2015, Pages 369-374

  Kuo, Chang Fu ^a,b,e   Grainge, Matthew J ^a   See, Lai Chu ^c,d   Yu, Kuang Hui ^b   Luo, Shue Fen ^b   Valdes, Ana M ^a   Zhang, Weiya ^a   Doherty, Michael ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d CHANG GUNG UNIVERSITY   (Taiwan)

^e NOTTINGHAM CITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ENVIRONMENTAL FACTOR; FAMILIAL INCIDENCE; FEMALE; FIRST DEGREE RELATIVE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE ENVIRONMENT INTERACTION; GOUT; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PREVALENCE; RISK FACTOR; SECOND DEGREE RELATIVE; SEX DIFFERENCE; TAIWAN; ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; CROSS-SECTIONAL STUDY; ENVIRONMENT; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; SEX RATIO; SOCIOECONOMICS; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; CROSS-SECTIONAL STUDIES; ENVIRONMENT; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GOUT; HUMANS; MALE; MIDDLE AGED; PREVALENCE; SEX DISTRIBUTION; SOCIOECONOMIC FACTORS; TAIWAN; YOUNG ADULT;

EID: 84921327133     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2013-204067     Document Type: Article

References (55)

1. Choi HK, Mount DB, Reginato AM, et al. Pathogenesis of gout. Ann Intern Med 2005;143:499-516.
2. Annemans L, Spaepen E, Gaskin M, et al. Gout in the UK and Germany: prevalence, comorbidities and management in general practice 2000-2005. Ann Rheum Dis 2008;67:960-6.
3. Zhu Y, Pandya BJ, Choi HK. Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008. Arthritis Rheum 2011;63:3136-41.
4. Winnard D, Wright C, Taylor WJ, et al. National prevalence of gout derived from administrative health data in Aotearoa New Zealand. Rheumatology (Oxford) 2012;51:901-9.
5. Ab. Usbott RD, Brand FN, Kannel WB, et al. Gout and coronary heart disease: the Framingham Study. J Clin Epidemiol 1988;41:237-42.
6. Krishnan E, Baker JF, Furst DE, et al. Gout and the risk of acute myocardial infarction. Arthritis Rheum 2006;54:2688-96.
7. Sheane BJ, Cunnane G. Tophaceous gout and chronic kidney disease. J Clin Rheumatol 2007;13:293.
8. Choi HK, Curhan G. Independent impact of gout on mortality and risk for coronary heart disease. Circulation 2007;116:894-900.
9. Krishnan E, Svendsen K, Neaton JD, et al. Long-term cardiovascular mortality among middle-aged men with gout. Arch Intern Med 2008;168:1104-10.
10. Kuo CF, See LC, Luo SF, et al. Gout: an independent risk factor for all-cause and cardiovascular mortality. Rheumatology (Oxford) 2010;49:141-6.
11. Mituszova M, Judak A, Poor G, et al . Clinical and family studies in Hungarian patients with gout. Rheumatol Int 1992;12:165-8.
12. Blumberg BS. Heredity of gout and hyperuricemia. Arthritis Rheum 1965;8:627-47.
13. Emmerson BT. Heredity in primary gout. Australas Ann Med 1960;9:168-75.
14. Hauge M, Harvald B. Heredity in gout and hyperuricemia. Acta Med Scand 1955;152:247-57.
15. Smyth CJ, Cotterman CW, Freyberg RH. The genetics of gout and hyperuricaemia. Ann Rheum Dis 1948;7:248.
16. Smyth CJ, Cotterman CW, Freyberg RH. The genetics of gout and hyperuricaemia; an analysis of 19 families. J Clin Invest 1948;27:749-59.
17. Grahame R, Scott JT. Clinical survey of 354 patients with gout. Ann Rheum Dis 1970;29:461-8.
18. Copeman WSC. A short history of the gout and the rheumatic diseases. Berkeley: University of California Press, 1964.
19. Cobb S. The frequency of the rheumatic diseases. Cambridge: Harvard University Press, 1971.
20. Reginato AM, Mount DB, Yang I, et al. The genetics of hyperuricaemia and gout. Nat Rev Rheumatol 2012;8:610-21.
21. Arromdee E, Michet CJ, Crowson CS, et al. Epidemiology of gout: is the incidence rising? J Rheumatol 2002;29:2403-06.
22. Mikuls TR, Saag KG. New insights into gout epidemiology. Curr Opin Rheumatol 2006;18:199-203.
23. Choi HK, Atkinson K, Karlson EW, et al. Obesity, weight change, hypertension, diuretic use, and risk of gout in men: the health professionals follow-up study. Arch Intern Med 2005;165:742-8.
24. Edwards NL. The role of hyperuricemia and gout in kidney and cardiovascular disease. Cleve Clin J Med 2008;75(Suppl 5):S13-16.
25. Bhole V, de Vera M, Rahman MM, et al. Epidemiology of gout in women: fifty-two-year followup of a prospective cohort. Arthritis Rheum 2010;62:1069-76.
26. Choi HK, Atkinson K, Karlson EW, et al. Obesity, weight change, hypertension, diuretic use, and risk of gout in men - The health professionals follow-up study. Arch Intern Med 2005;165:742-8.
27. Hueskes BA, Roovers EA, Mantel-Teeuwisse AK, et al. Use of diuretics and the risk of gouty arthritis: a systematic review. Semin Arthritis Rheum 2012;41:879-89.
28. Choi HK, Curhan G. Gout: epidemiology and lifestyle choices. Curr Opin Rheumatol 2005;17:341-5.
29. Choi HK, Atkinson K, Karlson EW, et al. Alcohol intake and risk of incident gout in men: a prospective study. Lancet 2004;363:1277-81.
30. Wilk JB, Djousse L, Borecki I, et al. Segregation analysis of serum uric acid in the NHLBI Family Heart Study. Hum Genet 2000;106:355-9.
31. Vitart V, Rudan I, Hayward C, et al. SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Nat Genet 2008;40:437-42.
32. Kolz M, Johnson T, Sanna S, et al. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet 2009;5:e1000504.
33. Dehghan A, Kottgen A, Yang Q, et al. Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet 2008;372:1953-61.
34. Kottgen A, Albrecht E, Teumer A, et al. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet 2013;45:145-54.
35. Wang WH, Chang SJ, Wang TN, et al. Complex segregation and linkage analysis of familial gout in Taiwanese aborigines. Arthritis Rheum 2004;50:242-6.
36. Krishnan E, Lessov-Schlaggar CN, Krasnow RE, et al. Nature versus nurture in gout: a twin study. Am J Med 2012;125:499-504.
37. Lin KC, Lin HY, Chou P. Community based epidemiological study on hyperuricemia and gout in Kin-Hu, Kinmen. J Rheumatol 2000;27:1045-50.
38. Directorate General of Budget, Accounting and Statistics, Executive Yuan, Taiwan. Population by sex, rate of population increase, average persons per household, density and natural increase rate. http://eng.stat.gov.tw/lp.asp?ctNode=2265&CtUnit=1072&BaseDSD=36&MP=5 (accessed 15 Aug 2013).
39. Chou CT, Lai JS. The epidemiology of hyperuricaemia and gout in Taiwan aborigines. Br J Rheumatol 1998;37:258-62.
40. Risch N. Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 1990;46:222-8.
41. Lin DY. Cox regression analysis of multivariate failure time data: the marginal approach. Stat Med 1994;13:2233-47.
42. Lee J, Chia KS. Estimation of prevalence rate ratios for cross sectional data: an example in occupational epidemiology. Br J Ind Med 1993;50:861-2.
43. Falconer DS. The inheritance of liability to diseases with variable age of onset, with particular reference to diabetes mellitus. Ann Hum Genet 1967;31:1-20.
44. Reich T, James JW, Morris CA. The use of multiple thresholds in determining the mode of transmission of semi-continuous traits. Ann Hum Genet 1972;36:163-84.
45. Reich T, Rice J, Cloninger CR, et al. The use of multiple thresholds and segregation analysis in analyzing the phenotypic heterogeneity of multifactorial traits. Ann Hum Genet 1979;42:371-90.
46. Wray NR, Gottesman II. Using summary data from the danish national registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder. Front Genet 2012;3:118.
47. Ober C, Loisel DA, Gilad Y. Sex-specific genetic architecture of human disease. Nat Rev Genet 2008;9:911-22.
48. Cea Soriano L, Rothenbacher D, Choi HK, et al. Contemporary epidemiology of gout in the UK general population. Arthritis Res Ther 2011;13:R39.
49. Mikuls TR, Farrar JT, Bilker WB, et al. Gout epidemiology: results from the UK General Practice Research Database, 1990-1999. Ann Rheum Dis 2005;64:267-72.
50. De Souza A, Fernandes V, Ferrari AJ. Female gout: clinical and laboratory features. J Rheumatol 2005;32:2186-8.
51. Adamopoulos D, Vlassopoulos C, Seitanides B, et al. The relationship of sex steroids to uric acid levels in plasma and urine. Acta Endocrinol (Copenh) 1977;85:198-208.
52. Hak AE, Curhan GC, Grodstein F, et al. Menopause, postmenopausal hormone use and risk of incident gout. Ann Rheum Dis 2010;69:1305-9.
53. Lin YC, Yen LL, Chen SY, et al. Prevalence of overweight and obesity and its associated factors: findings from National Nutrition and Health Survey in Taiwan, 1993-1996. Prev Med 2003;37:233-41.
54. Wu SJ, Pan WH, Yeh NH, et al. Trends in nutrient and dietary intake among adults and the elderly: from NAHSIT 1993-1996 to 2005-2008. Asia Pac J Clin Nutr 2011;20:251-65.
55. Rice TK. Familial resemblance and heritability. Adv Genet 2008;60:35-49.