Fertility preservation for boys and adolescents facing sterilizing medical therapy

Translational Andrology and Urology

Volumn 3, Issue 4, 2014, Pages 382-390

  Hussein, Ahmed A ^a,b   Tran, Nam D ^c   Smith, James F ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CAIRO UNIVERSITY   (Egypt)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Boys; Cancer; Fertility preservation; Malignancy

Indexed keywords

EID: 84921000813     PISSN: 22234683     EISSN: 22234691     Source Type: Journal    
DOI: 10.3978/j.issn.2223-4683.2014.11.06     Document Type: Review

References (83)

1. DeSantis CE, Lin CC, Mariotto AB, et al. Cancer treatment and survivorship statistics, 2014. CA Cancer J Clin 2014;64:252-71.
2. Howlader N, Noone AM, Krapcho M, et al. eds. SEER Cancer Statistics Review, 1975-2010. Bethesda, MD: National Cancer Institute, 2013.
3. Grundy R, Gosden RG, Hewitt M, et al. Fertility preservation for children treated for cancer (1): scientific advances and research dilemmas. Arch Dis Child 2001;84:355-9.
4. Stevens MC, Mahler H, Parkes S. The health status of adult survivors of cancer in childhood. Eur J Cancer 1998;34:694-8.
5. Ethics Committee of the American Society for Reproductive Medicine. Fertility preservation and reproduction in cancer patients. Fertil Steril 2005;83:1622-8.
6. Meistrich ML, Finch M, da Cunha MF, et al. Damaging effects of fourteen chemotherapeutic drugs on mouse testis cells. Cancer Res 1982;42:122-31.
7. Littley MD, Shalet SM, Beardwell CG, et al. Radiation-induced hypopituitarism is dose-dependent. Clin Endocrinol (Oxf) 1989;31:363-73.
8. Shalet SM, Tsatsoulis A, Whitehead E, et al. Vulnerability of the human Leydig cell to radiation damage is dependent upon age. J Endocrinol 1989;120:161-5.
9. Castillo LA, Craft AW, Kernahan J, et al. Gonadal function after 12-Gy testicular irradiation in childhood acute lymphoblastic leukaemia. Med Pediatr Oncol 1990;18:185-9.
10. Wallace WH, Anderson RA, Irvine DS. Fertility preservation for young patients with cancer: who is at risk and what can be offered? Lancet Oncol 2005;6:209-18.
11. Waring AB, Wallace WH. Subfertility following treatment for childhood cancer. Hosp Med 2000;61:550-7.
12. Sklar C. Reproductive physiology and treatment-related loss of sex hormone production. Med Pediatr Oncol 1999;33:2-8.
13. Clayton PE, Shalet SM, Price DA, et al. Testicular damage after chemotherapy for childhood brain tumors. J Pediatr 1988;112:922-6.
14. Meistrich ML, Wilson G, Brown BW, et al. Impact of cyclophosphamide on long-term reduction in sperm count in men treated with combination chemotherapy for Ewing and soft tissue sarcomas. Cancer 1992;70:2703-12.
15. Gerl A, Mühlbayer D, Hansmann G, et al. The impact of chemotherapy on Leydig cell function in long term survivors of germ cell tumors. Cancer 2001;91:1297-303.
16. Sonmezer M, Oktay K. Fertility preservation in female patients. Hum Reprod Update 2004;10:251-66.
17. Loren AW, Mangu PB, Beck LN, et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol 2013;31:2500-10.
18. Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996;2:561-6.
19. Blay JY. A decade of tyrosine kinase inhibitor therapy: Historical and current perspectives on targeted therapy for GIST. Cancer Treat Rev 2011;37:373-84.
20. Kontzias A, Laurence A, Gadina M, et al. Kinase inhibitors in the treatment of immune-mediated disease. F1000 Med Rep 2012;4:5.
21. Mariani S, Basciani S, Fabbri A, et al. Severe oligozoospermia in a young man with chronic myeloid leukemia on long-term treatment with imatinib started before puberty. Fertil Steril 2011;95:1120.e15-7.
22. Seshadri T, Seymour JF, McArthur GA. Oligospermia in a patient receiving imatinib therapy for the hypereosinophilic syndrome. N Engl J Med 2004;351:2134-5.
23. Loren AW, Mangu PB, Beck LN, et al. Fertility Preservation for Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol 2013;31:2500-10.
24. Williams DH 4th, Karpman E, Sander JC, et al. Pretreatment semen parameters in men with cancer. J Urol 2009;181:736-40.
25. Kort JD, Eisenberg ML, Millheiser LS, et al. Fertility issues in cancer survivorship. CA Cancer J Clin 2014;64:118-34.
26. Pearce S, Steinberg Z, Eggener S. Critical evaluation of modified templates and current trends in retroperitoneal lymph node dissection. Curr Urol Rep 2013;14:511-7.
27. Pasquini M, Wang Z. Current use and outcomes of hematopoietic stem cell transplantation: CIBMTR summary slides 2009. Available online: http://www.cibmtr. org/PUBLICATIONS/Newsletter/index.html
28. Borgmann-Staudt A, Rendtorff R, Reinmuth S, et al. Fertility after allogeneic haematopoietic stem cell transplantation in childhood and adolescence. Bone Marrow Transplant 2012;47:271-6.
29. Rueffer U, Breuer K, Josting A, et al. Male gonadal dysfunction in patients with Hodgkin's disease prior to treatment. Ann Oncol 2001;12:1307-11.
30. Bajoria R, Chatterjee R. Hypogonadotrophic hypogonadism and diminished gonadal reserve accounts for dysfunctional gametogenesis in thalassaemia patients with iron overload presenting with infertility. Hemoglobin 2011;35:636-42.
31. De Sanctis V, Candini G, Giovannini M, et al. Abnormal seminal parameters in patients with thalassemia intermedia and low serum folate levels. Pediatr Endocrinol Rev 2011;8 Suppl 2:310-3.
32. Agbaraji VO, Scott RB, Leto S, et al. Fertility studies in sickle cell disease: semen analysis in adult male patients. Int J Fertil 1988;33:347-52.
33. Soliman AT, elZalabany MM, Ragab M, et al. Spontaneous and GnRH-provoked gonadotropin secretion and testosterone response to human chorionic gonadotropin in adolescent boys with thalassaemia major and delayed puberty. J Trop Pediatr 2000;46:79-85.
34. De Sanctis V, Atti G, Lucci M, et al. Endocrine assessment of hypogonadism in patients affected by thalassaemia major. Ric Clin Lab 1980;10:663-71.
35. Al-Rimawi HS, Jallad MF, Amarin ZO, et al. Pubertal evaluation of adolescent boys with beta-thalassemia major and delayed puberty. Fertil Steril 2006;86:886-90.
36. Schover LR, Brey K, Lichtin A, et al. Knowledge and experience regarding cancer, infertility, and sperm banking in younger male survivors. J Clin Oncol 2002;20:1880-9.
37. Andersen BL. Surviving cancer: the importance of sexual self-concept. Med Pediatr Oncol 1999;33:15-23.
38. Schover LR. Psychosocial aspects of infertility and decisions about reproduction in young cancer survivors: a review. Med Pediatr Oncol 1999;33:53-9.
39. Siimes MA, Rautonen J. Small testicles with impaired production of sperm in adult male survivors of childhood malignancies. Cancer 1990;65:1303-6.
40. Crofton PM, Thomson AB, Evans AE, et al. Is inhibin B a potential marker of gonadotoxicity in prepubertal children treated for cancer? Clin Endocrinol (Oxf) 2003;58:296-301.
41. Tournaye H, Goossens E, Verheyen G, et al. Preserving the reproductive potential of men and boys with cancer: current concepts and future prospects. Hum Reprod Update 2004;10:525-32.
42. Müller J, Sonksen J, Sommer P, et al. Cryopreservation of semen from pubertal boys with cancer. Med Pediatr Oncol 2000;34:191-4.
43. Yee S, Fuller-Thomson E, Dwyer C, et al. "Just what the doctor ordered": Factors associated with oncology patients' decision to bank sperm. Can Urol Assoc J 2012;6:E174-8.
44. Lee SJ, Schover LR, Partridge AH, et al. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol 2006;24:2917-31.
45. Acosta JM, Tiao G, Stein JE, et al. Temporary relocation of testes to the anterior abdominal wall before radiation therapy of the pelvis or perineum. J Pediatr Surg 2002;37:1232-3.
46. Fallat ME, Hutter J American Academy of Pediatrics Committee on Bioethics, et al. Preservation of fertility in pediatric and adolescent patients with cancer. Pediatrics 2008;121:e1461-9.
47. Nielsen CT, Skakkebaek NE, Richardson DW, et al. Onset of the release of spermatozoa (spermarche) in boys in relation to age, testicular growth, pubic hair, and height. J Clin Endocrinol Metab 1986;62:532-5.
48. Kulin HE, Frontera MA, Demers LM, et al. The onset of sperm production in pubertal boys. Relationship to gonadotropin excretion. Am J Dis Child 1989;143:190-3.
49. Hirsch M, Lunenfeld B, Modan M, et al. Spermarche-- the age of onset of sperm emission. J Adolesc Health Care 1985;6:35-9.
50. Schmiegelow ML, Sommer P, Carlsen E, et al. Penile vibratory stimulation and electroejaculation before anticancer therapy in two pubertal boys. J Pediatr Hematol Oncol 1998;20:429-30.
51. Sato T, Katagiri K, Kubota Y, et al. In vitro sperm production from mouse spermatogonial stem cell lines using an organ culture method. Nat Protoc 2013;8:2098-104.
52. Yokonishi T, Sato T, Komeya M, et al. Offspring production with sperm grown in vitro from cryopreserved testis tissues. Nat Commun 2014;5:4320.
53. Nowroozi MR, Ahmadi H, Rafiian S, et al. In vitro colonization of human spermatogonia stem cells: effect of patient's clinical characteristics and testicular histologic findings. Urology 2011;78:1075-81.
54. Huleihel M, Abuelhija M, Lunenfeld E. In vitro culture of testicular germ cells: regulatory factors and limitations. Growth Factors 2007;25:236-52.
55. Brinster RL, Avarbock MR. Germline transmission of donor haplotype following spermatogonial transplantation. Proc Natl Acad Sci U S A 1994;91:11303-7.
56. Brinster RL, Zimmermann JW. Spermatogenesis following male germ-cell transplantation. Proc Natl Acad Sci U S A 1994;91:11298-302.
57. Schlatt S, Rosiepen G, Weinbauer GF, et al. Germ cell transfer into rat, bovine, monkey and human testes. Hum Reprod 1999;14:144-50.
58. Honaramooz A, Behboodi E, Blash S, et al. Germ cell transplantation in goats. Mol Reprod Dev 2003;64:422-8.
59. Honaramooz A, Megee SO, Dobrinski I. Germ cell transplantation in pigs. Biol Reprod 2002;66:21-8.
60. Izadyar F, Den Ouden K, Stout TA, et al. Autologous and homologous transplantation of bovine spermatogonial stem cells. Reproduction 2003;126:765-74.
61. Mikkola M, Sironen A, Kopp C, et al. Transplantation of normal boar testicular cells resulted in complete focal spermatogenesis in a boar affected by the immotile short-tail sperm defect. Reprod Domest Anim 2006;41:124-8.
62. Herrid M, Olejnik J, Jackson M, et al. Irradiation enhances the efficiency of testicular germ cell transplantation in sheep. Biol Reprod 2009;81:898-905.
63. Kim Y, Turner D, Nelson J, et al. Production of donor-derived sperm after spermatogonial stem cell transplantation in the dog. Reproduction 2008;136:823-31.
64. Hermann BP, Sukhwani M, Winkler F, et al. Spermatogonial stem cell transplantation into rhesus testes regenerates spermatogenesis producing functional sperm. Cell Stem Cell 2012;11:715-26.
65. Shinohara T, Inoue K, Ogonuki N, et al. Birth of offspring following transplantation of cryopreserved immature testicular pieces and in-vitro microinsemination. Hum Reprod 2002;17:3039-45.
66. Goossens E, De Rycke M, Haentjens P, et al. DNA methylation patterns of spermatozoa and two generations of offspring obtained after murine spermatogonial stem cell transplantation. Hum Reprod 2009;24:2255-63.
67. Smith JF, Yango P, Altman E, et al. Testicular Niche Required for Human Spermatogonial Stem Cell Expansion. Stem Cells Transl Med 2014;3:1043-54.
68. Shaw JM, Bowles J, Koopman P, et al. Fresh and cryopreserved ovarian tissue samples from donors with lymphoma transmit the cancer to graft recipients. Hum Reprod 1996;11:1668-73.
69. Shaw J, Trounson A. Oncological implications in the replacement of ovarian tissue. Hum Reprod 1997;12:403-5.
70. Thomson AB, Anderson RA, Irvine DS, et al. Investigation of suppression of the hypothalamic-pituitary-gonadal axis to restore spermatogenesis in azoospermic men treated for childhood cancer. Hum Reprod 2002;17:1715-23.
71. Schlegel PN, Su LM. Physiological consequences of testicular sperm extraction. Hum Reprod 1997;12:1688-92.
72. Malkin D, Portwine C. The genetics of childhood cancer. Eur J Cancer 1994;30A:1942-6.
73. Shields PG, Harris CC. Cancer risk and low-penetrance susceptibility genes in gene-environment interactions. J Clin Oncol 2000;18:2309-15.
74. Hawkins MM, Draper GJ, Smith RA. Cancer among 1,348 offspring of survivors of childhood cancer. Int J Cancer 1989;43:975-8.
75. Li FP, Fine W, Jaffe N, et al. Offspring of patients treated for cancer in childhood. J Natl Cancer Inst 1979;62:1193-7.
76. Nieman CL, Kinahan KE, Yount SE, et al. Fertility preservation and adolescent cancer patients: lessons from adult survivors of childhood cancer and their parents. Cancer Treat Res 2007;138:201-17.
77. Kazak AE, Boeving CA, Alderfer MA, et al. Posttraumatic stress symptoms during treatment in parents of children with cancer. J Clin Oncol 2005;23:7405-10.
78. Wu AK, Odisho AY, Washington SL 3rd, et al. Out-of-pocket fertility patient expense: data from a multicenter prospective infertility cohort. J Urol 2014;191:427-32.
79. Ondrusek N, Abramovitch R, Pencharz P, et al. Empirical examination of the ability of children to consent to clinical research. J Med Ethics 1998;24:158-65.
80. Grundy R, Larcher V, Gosden RG, et al. Fertility preservation for children treated for cancer (2): ethics of consent for gamete storage and experimentation. Arch Dis Child 2001;84:360-2.
81. McIntosh N, Bates P, Brykczynska G, et al. Guidelines for the ethical conduct of medical research involving children. Royal College of Paediatrics, Child Health: Ethics Advisory Committee. Arch Dis Child 2000;82:177-82.
82. Babayev SN, Arslan E, Kogan S, et al. Evaluation of ovarian and testicular tissue cryopreservation in children undergoing gonadotoxic therapies. J Assist Reprod Genet 2013;30:3-9.
83. English V, Mussell R, Sheather J, et al. Review of the Human Fertilisation and Embryology Act 1990. J Med Ethics 2005;31:743-4.