A new era for the treatment of hyperkalemia?

New England Journal of Medicine

Volumn 372, Issue 3, 2015, Pages 275-277

  Ingelfinger, Julie R ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

PATIROMER; POTASSIUM; SODIUM ZIRCONIUM CYCLOSILICATE; POLYMER; SILICATE;

CHRONIC KIDNEY DISEASE; CLINICAL TRIAL (TOPIC); CONSTIPATION; DIET THERAPY; DISEASE CONTROL; DIURETIC THERAPY; DRUG MECHANISM; EDITORIAL; HEART DISEASE; HUMAN; HYPERKALEMIA; HYPOKALEMIA; PHASE 3 CLINICAL TRIAL (TOPIC); POTASSIUM BLOOD LEVEL; TREATMENT OUTCOME; DRUG EFFECTS; FEMALE; MALE; RENAL INSUFFICIENCY, CHRONIC; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

FEMALE; HUMANS; HYPERKALEMIA; MALE; POLYMERS; RENAL INSUFFICIENCY, CHRONIC; RENIN-ANGIOTENSIN SYSTEM; SILICATES;

EID: 84920996932     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1414112     Document Type: Editorial

References (7)

1. Burnell JM, Scribner BH, Uyeno BT, Villamil MF. The effect in humans of extracellular pH change on the relationship between serum potassium concentration and intracellular potassium. J Clin Invest 1956;35:935-9.
2. Kovesdy CP. Management of hyperkalaemia in chronic kidney disease. Nat Rev Nephrol 2014;10:653-62.
3. Persson F, Rossing P. Sequential RAAS blockade: is it worth the risk? Adv Chronic Kidney Dis 2014;21:159-65.
4. Arroyo D, Panizo N, García de Vinuesa S, Goicoechea M, Verdalles U, Luño J. Hypercalcemia as a side effect of potassium binding agents. Nefrologia 2012;32:655-8.
5. Weir MR, Bakris GL, Bushinsky DA, et al. Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors. N Engl J Med 2015;372:211-21.
6. Packham DK, Rasmussen HS, Lavin PT, et al. Sodium zirconium cyclosilicate in hyperkalemia. N Engl J Med 2015;372:222-31.
7. Kosiborod M, Rasmussen HS, Lavin P, et al. Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: the HARMONIZE randomized clinical trial. JAMA 2014 November 17 (Epub ahead of print).