Patterns of Complementary and Alternative Medicine (CAM) use in children: a systematic review

European Journal of Pediatrics

Volumn 173, Issue 11, 2014, Pages 1413-1428

  Italia, Salvatore ^a,b   Wolfenstetter, Silke Britta ^b   Teuner, Christina Maria ^b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Child; Complementary therapies; Drug utilization; Homeopathy; Phytotherapy; Socioeconomic factors

Indexed keywords

HERBACEOUS AGENT;

ALTERNATIVE MEDICINE; EDUCATIONAL STATUS; HOMEOPATHY; HUMAN; INCOME; PREVALENCE; PRIORITY JOURNAL; REVIEW; SOCIOECONOMICS; SYSTEMATIC REVIEW; ADOLESCENT; CHILD; FACTUAL DATABASE; FEMALE; MALE; PHYTOTHERAPY; STATISTICS AND NUMERICAL DATA; UTILIZATION;

ADOLESCENT; CHILD; COMPLEMENTARY THERAPIES; DATABASES, FACTUAL; FEMALE; HOMEOPATHY; HUMANS; MALE; PHYTOTHERAPY; PREVALENCE; SOCIOECONOMIC FACTORS;

EID: 84920973842     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-014-2300-z     Document Type: Review

References (72)

1. Alves AR, da Silva MJ (2003) Use of phytotherapy in children up to 5 years of age in a central and peripheral area of the city of Sao Paulo. Rev Esc Enferm USP 37:85–91, Portuguese
2. Araz N, Bulbul S (2011) Use of complementary and alternative medicine in a pediatric population in southern Turkey. Clin Invest Med 34:21–29
3. Armishaw J, Grant CC (1999) Use of complementary treatment by those hospitalised with acute illness. Arch Dis Child 81:133–137
4. Barnes PM, Bloom B, Nahin RL (2008) Complementary and alternative medicine use among adults and children: United States, 2007. Natl Health Stat Rep 12:1–23
5. Bellas A, Lafferty WE, Lind B, Tyree PT (2005) Frequency, predictors, and expenditures for pediatric insurance claims for complementary and alternative medical professionals in Washington State. Arch Pediatr Adolesc Med 159:367–372. doi:10.1001/archpedi.159.4.367
6. Birdee GS, Phillips RS, Davis RB, Gardiner P (2010) Factors associated with pediatric use of complementary and alternative medicine. Pediatrics 125:249–256. doi:10.1542/peds.2009-1406
7. Bishop FL, Prescott P, Chan YK, Saville J, von Elm E, Lewith GT (2010) Prevalence of complementary medicine use in pediatric cancer: a systematic review. Pediatrics 125:768–776. doi:10.1542/peds.2009-1775
8. Braun CA, Bearinger LH, Halcón LL, Pettingell SL (2005) Adolescent use of complementary therapies. J Adolesc Health 37:76. doi:10.1016/j.jadohealth.2004.07.010
9. Chen LL, Huang LC, Lin SC, Smith M, Liu SJ (2009) Use of folk remedies among families of children hospitalised in Taiwan. J Clin Nurs 18:2162–2170. doi:10.1111/j.1365-2702.2008.02539.x
10. Cincotta DR, Crawford NW, Lim A, Cranswick NE, Skull S, South M, Powell CV (2006) Comparison of complementary and alternative medicine use: reasons and motivations between two tertiary children’s hospitals. Arch Dis Child 91:153–158. doi:10.1136/adc.2005.074872
11. Crawford NW, Cincotta DR, Lim A, Powell CV (2006) A cross-sectional survey of complementary and alternative medicine use by children and adolescents attending the University Hospital of Wales. BMC Complement Altern Med 6:16. doi:10.1186/1472-6882-6-16
12. Crowe S, Lyons B (2004) Herbal medicine use by children presenting for ambulatory anesthesia and surgery. Paediatr Anaesth 14:916–919. doi:10.1111/j.1460-9592.2004.01353.x
13. Dolceamore TR, Altomare F, Zurlo F, Miniero R (2012) Use of alternative-complementary-medicine (CAM) in Calabrian children. Ital J Pediatr 38:70. doi:10.1186/1824-7288-38-70
14. Du Y, Knopf H (2009) Paediatric homoeopathy in Germany: results of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS). Pharmacoepidemiol Drug Saf 18:370–379. doi:10.1002/pds.1720
15. Eardley S, Bishop FL, Prescott P, Cardini F, Brinkhaus B, Santos-Rey K, Vas J, von Ammon K, Hegyi G, Dragan S, Uehleke B, Fønnebø V, Lewith G (2012) A systematic literature review of complementary and alternative medicine prevalence in EU. Forsch Komplementmed 19(Suppl 2):18–28. doi:10.1159/000342708
16. Ernst E (1999) Prevalence of complementary/alternative medicine for children: a systematic review. Eur J Pediatr 158:7–11
17. Ernst E (2008) The truth about homeopathy. Br J Clin Pharmacol 65:163–164. doi:10.1111/j.1365-2125.2007.03007.x
18. Everett LL, Birmingham PK, Williams GD, Brenn BR, Shapiro JH (2005) Herbal and homeopathic medication use in pediatric surgical patients. Paediatr Anaesth 15:455–460. doi:10.1111/j.1460-9592.2005.01487.x
19. Eymann A, Bellomo MM, Catsicaris C, Wahren C (2009) Utilización de medicina alternativa o complementaria en una población pediátrica de un hospital de comunidad [Use of alternative or complementary medicine by the pediatric population of a community hospital]. Arch Argent Pediatr 107:321–328. doi:10.1590/s0325-00752009000400009, Spanish
20. Feiler-Mircus N (2012) P04.44. The association between the use of complementary and alternative medicine in children with demographic indicators and vaccinations. BMC Complement Altern Med 12(Suppl 1):314. doi:10.1186/1472-6882-12-S1-P314
21. Feldmann JM, Wiemann CM, Sever L, Hergenroeder AC (2008) Folk and traditional medicine use by a subset of Hispanic adolescents. Int J Adolesc Med Health 20:41–51
22. Fong DP, Fong LK (2002) Usage of complementary medicine among children. Aust Fam Physician 31:388–391
23. Frass M, Strassl RP, Friehs H, Müllner M, Kundi M, Kaye AD (2012) Use and acceptance of complementary and alternative medicine among the general population and medical personnel: a systematic review. Ochsner J 12:45–56
24. Gentil LB, Robles AC, Grosseman S (2010) Uso de terapias complementares por mães em seus filhos: estudo em um hospital universitário [Use of complementary therapies by mothers in their children: study at an university hospital]. Cien Saude Colet 15(Suppl 1):1293–1299, Portuguese
25. German Pharmaceutical Industry Association (2012) Pharmadaten 2012: data on the German pharmaceutical market 2012. Available at: www.bpi.de/daten-und-fakten/pharmadaten/. Accessed 1 Aug 2013
26. Graham ME, Brake MK, Taylor SM, Flowerdew G, Hong P (2013) Complementary and alternative medicine use among patients presenting to a pediatric otolaryngology clinic. Int J Pediatr Otorhinolaryngol 77:721–725. doi:10.1016/j.ijporl.2013.01.026
27. Headley J, Northstone K (2007) Medication administered to children from 0 to 7.5 years in the Avon Longitudinal Study of Parents and Children (ALSPAC). Eur J Clin Pharmacol 63:189–195. doi:10.1007/s00228-006-0231-y
28. Hughes SC, Wingard DL (2006) Children’s visits to providers of complementary and alternative medicine in San Diego. Ambul Pediatr 6:293–296. doi:10.1016/j.ambp.2005.11.007
29. Huillet A, Erdie-Lalena C, Norvell D, Davis BE (2011) Complementary and alternative medicine used by children in military pediatric clinics. J Altern Complement Med 17:531–537. doi:10.1089/acm.2010.0339
30. Hümer M, Scheller G, Kapellen T, Gebauer C, Schmidt H, Kiess W (2010) Phytotherapie in der Kinderheilkunde: Prävalenz, Indikationen und Motivation [Use of herbal medicine in German children—prevalence, indications and motivation]. Dtsch Med Wochenschr 135:959–964. doi:10.1055/s-0030-1253683, German
31. Italia S, Batscheider A, Heinrich J, Wenig C, Bauer CP, Koletzko S, Lehmann I, Herbarth O, von Berg A, Berdel D, Hoffmann B, Schaaf B, Wolfenstetter SB (2012) Utilization and costs of conventional and alternative pharmaceuticals in children: results from the German GINIplus and LISAplus birth cohort studies. Pharmacoepidemiol Drug Saf 21:1102–1111. doi:10.1002/pds.3323
32. Jean D, Cyr C (2007) Use of complementary and alternative medicine in a general pediatric clinic. Pediatrics 120:e138–e141. doi:10.1542/peds.2006-3105
33. Jeschke E, Ostermann T, Tabali M, Kröz M, Bockelbrink A, Witt CM, Willich SN, Matthes H (2011) Anthroposophic medicine in pediatric primary care: a prospective, multicenter observational study on prescribing patterns. Altern Ther Health Med 17:18–28
34. Kim JH, Nam CM, Kim MY, Lee DC (2012) The use of complementary and alternative medicine (CAM) in children: a telephone-based survey in Korea. BMC Complement Altern Med 12:46. doi:10.1186/1472-6882-12-46
35. Lanski SL, Greenwald M, Perkins A, Simon HK (2003) Herbal therapy use in a pediatric emergency department population: expect the unexpected. Pediatrics 111(5 Pt 1):981–985
36. Lim A, Cranswick N, Skull S, South M (2005) Survey of complementary and alternative medicine use at a tertiary children’s hospital. J Paediatr Child Health 41:424–427. doi:10.1111/j.1440-1754.2005.00659.x
37. Lin YC, Bioteau AB, Ferrari LR, Berde CB (2004) The use of herbs and complementary and alternative medicine in pediatric preoperative patients. J Clin Anesth 16:4–6. doi:10.1016/j.jclinane.2003.03.005
38. Loman DG (2003) The use of complementary and alternative health care practices among children. J Pediatr Health Care 17:58–63. doi:10.1067/mph.2003.29
39. Losier A, Taylor B, Fernandez CV (2005) Use of alternative therapies by patients presenting to a pediatric emergency department. J Emerg Med 28:267–271. doi:10.1016/j.jemermed.2004.11.019
40. Low E, Murray DM, O’Mahony O, O’B Hourihane J (2008) Complementary and alternative medicine use in Irish paediatric patients. Ir J Med Sci 177:147–150. doi:10.1007/s11845-008-0152-0
41. Madsen H, Andersen S, Nielsen RG, Dolmer BS, Høst A, Damkier A (2003) Use of complementary/alternative medicine among paediatric patients. Eur J Pediatr 162:334–341. doi:10.1007/s00431-003-1180-4
42. Mallet P, Mourdi N, Dubus JC, Bavoux F, Boyer-Gervoise MJ, Jean-Pastor MJ, Chalumeau M (2011) Respiratory paradoxical adverse drug reactions associated with acetylcysteine and carbocysteine systemic use in paediatric patients: a national survey. PLoS One 6(7):e22792. doi:10.1371/journal.pone.0022792
43. Menniti-Ippolito F, Forcella E, Bologna E, Gargiulo L, Traversa G, Raschetti R (2002) Use of unconventional medicine in children in Italy. Eur J Pediatr 161:690. doi:10.1007/s00431-002-1085-7
44. Ottolini MC, Hamburger EK, Loprieato JO, Coleman RH, Sachs HC, Madden R, Brasseux C (2001) Complementary and alternative medicine use among children in the Washington, DC area. Ambul Pediatr 1:122–125
45. Ozturk C, Karayagiz G (2008) Exploration of the use of complementary and alternative medicine among Turkish children. J Clin Nurs 17:2558–2564. doi:10.1111/j.1365-2702.2008.02329.x
46. Pitetti R, Singh S, Hornyak D, Garcia SE, Herr S (2001) Complementary and alternative medicine use in children. Pediatr Emerg Care 17:165–16
47. Quandt SA, Verhoef MJ, Arcury TA, Lewith GT, Steinsbekk A, Kristoffersen AE, Wahner-Roedler DL, Fønnebø V (2009) Development of an international questionnaire to measure use of complementary and alternative medicine (I-CAM-Q). J Altern Complement Med 15:331–339. doi:10.1089/acm.2008.0521
48. Robinson N, Blair M, Lorenc A, Gully N, Fox P, Mitchell K (2008) Complementary medicine use in multi-ethnic paediatric outpatients. Complement Ther Clin Pract 14:17–24. doi:10.1016/j.ctcp.2007.07.003
49. Sanz E, Hernández MA, Ratchina S, Stratchounsky L, Peiré MA, Lapeyre-Mestre M, Horen B, Kriska M, Krajnakova H, Momcheva H, Encheva D, Martínez-Mir I, Palop V (2004) Drug utilisation in outpatient children. A comparison among Tenerife, Valencia, and Barcelona (Spain), Toulouse (France), Sofia (Bulgaria), Bratislava (Slovakia) and Smolensk (Russia). Eur J Clin Pharmacol 60:127–134. doi:10.1007/s00228-004-0739-y
50. Sawni A, Ragothaman R, Thomas RL, Mahajan P (2007) The use of complementary/alternative therapies among children attending an urban pediatric emergency department. Clin Pediatr (Phila) 46(1):36–41
51. Sawni-Sikand A, Schubiner H, Thomas RL (2002) Use of complementary/alternative therapies among children in primary care pediatrics. Ambul Pediatr 2:99–103
52. Sikich N, Petroz G, Lerman J (2002) Herbal medicine use in children scheduled for anaesthesia. Can J Anaesth 49:35
53. Simpson N, Pearce A, Finlay F, Lenton S (1998) The use of complementary medicine in paediatric outpatient clinics. Ambul Child Health 3:351–356
54. Simpson N, Roman K (2001) Complementary medicine use in children: extent and reasons. A population-based study. Br J Gen Pract 51:914–916
55. Siponen SM, Ahonen RS, Kettis A, Hämeen-Anttila KP (2012) Complementary or alternative? Patterns of complementary and alternative medicine (CAM) use among Finnish children. Eur J Clin Pharmacol 68:1639–1645. doi:10.1007/s00228-012-1294-6
56. Smith C, Eckert K (2006) Prevalence of complementary and alternative medicine and use among children in South Australia. J Paediatr Child Health 42:538–543. doi:10.1111/j.1440-1754.2006.00918.x
57. Spigelblatt L, Lâiné-Ammara G, Pless IB, Guyver A (1994) The use of alternative medicine by children. Pediatrics 94(6 Pt 1):811–814
58. Steinsbekk A, Rise MB, Bishop F, Lewith G (2011) Predictors for adolescent visits to practitioners of complementary and alternative medicine in a total population (the Young-HUNT Studies). PLoS One 6(10):e25719. doi:10.1371/journal.pone.0025719
59. Surette S, Vanderjagt L, Vohra S (2013) Surveys of complementary and alternative medicine usage: a scoping study of the paediatric literature. Complement Ther Med 21(Suppl 1):48–53. doi:10.1016/j.ctim.2011.08.006
60. Thompson EA, Bishop JL, Northstone K (2010) The use of homeopathic products in childhood: data generated over 8.5 years from the Avon Longitudinal Study of Parents and Children (ALSPAC). J Altern Complement Med 16:69–79. doi:10.1089/acm.2009.0007
61. Verhoef MJ, Russell ML, Love EJ (1994) Alternative medicine use in rural alberta. Can J Public Health 85:308–309
62. Vlieger AM, van de Putte EM, Hoeksma H (2006) The use of complementary and alternative medicine in children at a general paediatric clinic and parental reasons for use. Ned Tijdschr Geneeskd 150:625–630, Dutch
63. Weissenstein A, Straeter A, Villalon G, Luchter E, Bittmann S (2012) High frequency of CAM use among children in Germany. J Altern Complement Med 18:729–730. doi:10.1089/acm.2012.0398
64. Wilson KM, Klein JD (2002) Adolescents’ use of complementary and alternative medicine. Ambul Pediatr 2:104–110
65. Wilson KM, Klein JD, Sesselberg TS, Yussman SM, Markow DB, Green AE, West JC, Gray NJ (2006) Use of complementary medicine and dietary supplements among U.S. adolescents. J Adolesc Health 38:385–394. doi:10.1016/j.jadohealth.2005.01.010
66. Wolthers OD (1989) Use of alternative forms of treatment by patients attending a pediatric outpatient clinic. A questionnaire study. Ugeskr Laeger 151:87–90, Danish
67. Wye L, Hay AD, Northstone K, Bishop J, Headley J, Thompson E (2008) Complementary or alternative? The use of homeopathic products and antibiotics amongst pre-school children. BMC Fam Pract 9:8. doi:10.1186/1471-2296-9-8
68. Yussman SM, Ryan SA, Auinger P, Weitzman M (2004) Visits to complementary and alternative medicine providers by children and adolescents in the United States. Ambul Pediatr 4:429–435. doi:10.1367/a03-091r1.1
69. Yussman SM, Wilson KM, Klein JD (2006) Herbal products and their association with substance use in adolescents. J Adolesc Health 38:395–400. doi:10.1016/j.jadohealth.2004.10.015
70. Zutavern A, Schaaf B, von Berg A, Borte M, Herbarth O, Wichmann H, Heinrich J (2007) Inanspruchnahme von Homöopathie und Konsultation von Heilpraktikern - Ergebnisse einer deutschen Geburtskohortenstudie (LISA) im Alter von 2 Jahren [Use of homeopathy and consultation with alternative medicine practitioners: Results of a German birth cohort study (LISA) at the age of 2 years]. Monatsschrift Kinderheilkunde 155:439–445. doi:10.1007/s00112-007-1497-6, German
71. Zuzak TJ, Boňková J, Careddu D, Garami M, Hadjipanayis A, Jazbec J, Merrick J, Miller J, Ozturk C, Persson IA, Petrova G, Saz Peiró P, Schraub S, Simões-Wüst AP, Steinsbekk A, Stockert K, Stoimenova A, Styczynski J, Tzenova-Savova A, Ventegodt S, Vlieger AM, Längler A (2013) Use of complementary and alternative medicine by children in Europe: published data and expert perspectives. Complement Ther Med 21(Suppl 1):34–47. doi:10.1016/j.ctim.2012.01.001
72. Zuzak TJ, Zuzak-Siegrist I, Simões-Wüst AP, Rist L, Staubli G (2009) Use of complementary and alternative medicine by patients presenting to a paediatric emergency department. Eur J Pediatr 168:431–437. doi:10.1007/s00431-008-0765-3