Disturbed adiponectin - AMPK system in skeletal muscle of patients with metabolic syndrome

European Journal of Preventive Cardiology

Volumn 22, Issue 2, 2015, Pages 203-205

  Berendoncks, An M Van ^a   Stensvold, Dorthe ^b   Garnier, Anne ^c   Fortin, Dominique ^c   Sente, Tahnee ^a   Vrints, Christiaan J ^a   Arild, Slørdahl Stig ^b   Ventura Clapier, Renee ^c   Wisløff, Ulrik ^b   Conraads, Viviane M ^a  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Adiponectin; AMPK; metabolic syndrome; skeletal muscle

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR 1; C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ADIPONECTIN RECEPTOR; ADIPOR1 PROTEIN, HUMAN; MESSENGER RNA; PRKAA1 PROTEIN, HUMAN; PRKAA2 PROTEIN, HUMAN;

ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DYSLIPIDEMIA; ENZYME ACTIVATION; GLUCOSE METABOLISM; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; LIPID METABOLISM; METABOLIC SYNDROME X; MUSCLE BIOPSY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; METABOLISM;

ADIPONECTIN; AMP-ACTIVATED PROTEIN KINASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; METABOLIC SYNDROME X; MUSCLE, SKELETAL; RECEPTORS, ADIPONECTIN; RNA, MESSENGER;

EID: 84920938599     PISSN: 20474873     EISSN: 20474881     Source Type: Journal    
DOI: 10.1177/2047487313508034     Document Type: Article

References (10)

1. Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev. 2005 ; 26: 439-451
2. Bluher M, Bullen JW, Lee JH, et al. Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training. J Clin Endocrinol Metab. 2006 ; 91: 2310-2316
3. Santaniemi M, Ukkola O, Malo E, et al. Metabolic syndrome in the prediction of cardiovascular events: the potential additive role of hsCRP and adiponectin. Eur J Prev Cardiol 2014; 21: 1242-1248.
4. Chen MB, McAinch AJ, Macaulay SL, et al. Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabetics. J Clin Endocrinol Metab. 2005 ; 90: 3665-3672
5. Bruce CR, Mertz VA, Heigenhauser GJ, et al. The stimulatory effect of globular adiponectin on insulin-stimulated glucose uptake and fatty acid oxidation is impaired in skeletal muscle from obese subjects. Diabetes. 2005 ; 54: 3154-3160
6. Tsuchida A, Yamauchi T, Ito Y, et al. Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J Biol Chem. 2004 ; 279: 30817-30822
7. Van Berendoncks AM, Garnier A, Beckers P, et al. Functional adiponectin resistance at the level of the skeletal muscle in mild to moderate chronic heart failure. Circ Heart Fail. 2010 ; 3: 185-194
8. Van Berendoncks AM, Conraads VM, Van Leuven W, et al. Validation of an adiponectin immunoassay in human skeletal muscle biopsies. J Immunol Methods. 2010 ; 362: 209-212
9. Stensvold D, Tjonna AE, Skaug EA, et al. Strength training vs. aerobic interval training to modify risk factors of metabolic syndrome. J Appl Physiol. 2010 ; 108: 804-810
10. Wallace TM, Levy JC, Matthews DR, et al. Use and abuse of HOMA modeling. Diabetes Care. 2004 ; 27: 1487-1495