Effective near-infrared photodynamic therapy assisted by upconversion nanoparticles conjugated with photosensitizers

International Journal of Nanomedicine

Volumn 10, Issue , 2015, Pages 419-432

  Dou, Qing Qing ^a   Teng, Choon Peng ^a   Ye, Enyi ^a   Loh, Xian Jun ^a,b,c  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

Author keywords

Live dead assay; MTT assay; Nanocomplex; Singlet oxygen generation rate

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CHLORIN E6 CONJUGATED UPCONVERSION NANOPARTICLE; SINGLET OXYGEN; UNCLASSIFIED DRUG; UPCONVERSION NANOPARTICLE; NANOPARTICLE; PHOTOSENSITIZING AGENT;

ARTICLE; CELL ASSAY; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED RADIATION; MCF 7 CELL LINE; MTT ASSAY; NEAR INFRARED PHOTODYNAMIC THERAPY; OXYGEN CONCENTRATION; PHOTODYNAMIC THERAPY; SINGLET OXYGEN GENERATION RATE; TISSUE DISTRIBUTION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; MCF-7 CELL LINE; PHOTOCHEMOTHERAPY; PROCEDURES;

CELL SURVIVAL; HUMANS; INFRARED RAYS; MCF-7 CELLS; NANOPARTICLES; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS;

EID: 84920885182     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S74891     Document Type: Article

References (57)

1. Nguyen NT, Schauer P, Luketich JD. Minimally invasive esophagectomy for Barrett’s esophagus with high-grade dysplasia. Surgery. 2000;127(3): 284-290.
2. Hirschberg H, Spetalen S, Carper S, Hole P, Tillung T, Madsen S. Minimally invasive photodynamic therapy (PDT) for ablation of experimental rat glioma. Minim Invasive Neurosurg. 2006;49(03):135-142.
3. Gossner L, Stolte M, Sroka R, et al. Photodynamic ablation of high-grade dysplasia and early cancer in Barrett’s esophagus by means of 5-aminolevulinic acid. Gastroenterology. 1998;114(3):448-455.
4. Dolmans DE, Fukumura D, Jain RK. Photodynamic therapy for cancer. Nat Rev Cancer. 2003;3(5):380-387.
5. Robertson C, Evans DH, Abrahamse H. Photodynamic therapy (PDT): a short review on cellular mechanisms and cancer research applications for PDT. J Photochem Photobiol B. 2009;96(1):1-8.
6. Brown SB, Brown EA, Walker I. The present and future role of photodynamic therapy in cancer treatment. Lancet Oncol. 2004;5(8):497-508.
7. Castano AP, Demidova TN, Hamblin MR. Mechanisms in photodynamic therapy: part one photosensitizers, photochemistry and cellular localization. Photodiagnosis Photodyn Ther. 2004;1(4):279-293.
8. Spikes JD. New trends in photobiology: chlorins as photosensitizers in biology and medicine. J Photochem Photobiol B. 1990;6(3):259-274.
9. Lukyanets EA. Phthalocyanines as photosensitizers in the photodynamic therapy of cancer. J Porphyrins Phthalocyanines. 1999;3(06): 424-432.
10. Guo H, Qian H, Idris NM, Zhang Y. Singlet oxygen-induced apoptosis of cancer cells using upconversion fluorescent nanoparticles as a carrier of photosensitizer. Nanomedicine. 2010;6(3):486-495.
11. Idris NM, Gnanasammandhan MK, Zhang J, Ho PC, Mahendran R, Zhang Y. In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers. Nat Med. 2012;18(10):1580-1585.
12. Bonnett R. Photosensitizers of the porphyrin and phthalocyanine series for photodynamic therapy. Chem Soc Rev. 1995;24(1):19-33.
13. Detty MR, Gibson SL, Wagner SJ. Current clinical and preclinical photo-sensitizers for use in photodynamic therapy. J Med Chem. 2004;47(16): 3897-3915.
14. Hirsch LR, Stafford RJ, Bankson JA, et al. Nanoshell-mediated nearinfrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci U S A. 2003;100(23):13549-13554.
15. Zhou J, Sun Y, Du X, Xiong L, Hu H, Li F. Dual-modality in vivo imaging using rare-earth nanocrystals with near-infrared to near-infrared (NIR-to-NIR) upconversion luminescence and magnetic resonance properties. Biomaterials. 2010;31(12):3287-3295.
16. Omar G, Wilson M, Nair S. Lethal photosensitization of woundassociated microbes using indocyanine green and near-infrared light. BMC Microbiol. 2008;8(1):111.
17. Funayama T, Sakane M, Abe T, Ochiai N. Photodynamic therapy with indocyanine green injection and near-infrared light irradiation has phototoxic effects and delays paralysis in spinal metastasis. Photomed Laser Surg. 2012;30(1):47-53.
18. Kogan BY, Butenin AV, Torshina NL, Kaliya OL, Lukyanets EA, Kogan EA. Aluminium sulphophthalocyanine as an NIR photosensitizer for PDT. Proc SPIE. 1999;3563:4.
19. Baumler W, Abels C, Karrer S, et al. Photo-oxidative killing of human colonic cancer cells using indocyanine green and infrared light. Br J Cancer. 1999;80(3-4):360-363.
20. Allison RR, Downie GH, Cuenca R, Hu X-H, Childs CJH, Sibata CH. Photosensitizers in clinical PDT. Photodiagn Photodyn Therapy. 2004; 1(1):27-42.
21. Chen G, Qiu H, Prasad PN, Chen X. Upconversion nanoparticles: design, nanochemistry, and applications in theranostics. Chem Rev. 2014; 114(10):5161-5214.
22. Haase M, Schäfer H. Upconverting nanoparticles. Angew Chem Int Ed. 2011; 50(26):5808-5829.
23. Park YI, Kim HM, Kim JH, et al. Theranostic probe based on lanthanidedoped nanoparticles for simultaneous in vivo dual-modal imaging and photodynamic therapy. Adv Mater. 2012;24(42):5755-5761.
24. Wang C, Cheng L, Liu Z. Drug delivery with upconversion nanoparticles for multi-functional targeted cancer cell imaging and therapy. Biomaterials. 2011;32(4):1110-1120.
25. Wu S, Han G, Milliron DJ, et al. Non-blinking and photostable upconverted luminescence from single lanthanide-doped nanocrystals. Proc Natl Acad Sci U S A. 2009;106(27):10917-10921.
26. Konan YN, Gurny R, Allémann E. State of the art in the delivery of photosensitizers for photodynamic therapy. J Photochem Photobiol B. 2002;66(2):89-106.
27. Zhang P, Steelant W, Kumar M, Scholfield M. Versatile photosensitizers for photodynamic therapy at infrared excitation. J Am Chem Soc. 2007; 129(15):4526-4527.
28. Qian HS, Guo HC, Ho PCL, Mahendran R, Zhang Y. MesoporousSilica-coated up-conversion fluorescent nanoparticles for photodynamic therapy. Small. 2009;5(20):2285-2290.
29. Lim ME, Lee YL, Zhang Y, Chu JJH. Photodynamic inactivation of viruses using upconversion nanoparticles. Biomaterials. 2012;33(6): 1912-1920.
30. Zhao Z, Han Y, Lin C, et al. Multifunctional core shell upconverting nanoparticles for imaging and photodynamic therapy of liver cancer cells. Chem Asian J. 2012;7(4):830.
31. Shan J, Budijono SJ, Hu G, et al. Pegylated composite nanoparticles containing upconverting phosphors and meso-tetraphenyl porphine (TPP) for photodynamic therapy. Adv Funct Mater. 2011;21(13): 2488-2495.
32. Wang HJ, Shrestha R, Zhang Y. Encapsulation of photosensitizers and upconversion nanocrystals in lipid micelles for photodynamic therapy. Part Part Syst Char. 2014;31(2):228-235.
33. Liu K, Liu X, Zeng Q, et al. Covalently assembled NIR nanoplatform for simultaneous fluorescence imaging and photodynamic therapy of cancer cells. ACS Nano. 2012;6(5):4054-4062.
34. Triesscheijn M, Baas P, Schellens JH, Stewart FA. Photodynamic therapy in oncology. Oncologist. 2006;11(9):1034-1044.
35. Chin WWL, Lau WKO, Heng PWS, Bhuvaneswari R, Olivo M. Fluorescence imaging and phototoxicity effects of new formulation of chlorin e6-polyvinylpyrrolidone. Proc Natl Acad Sci U S A. 2006;84(2): 103-110.
36. Čunderlíková B, Gangeskar L, Moan J. Acid-base properties of chlorin e6: relation to cellular uptake. J Photochem Photobiol B. 1999; 53(1-3):81-90.
37. Potvin PG, Luyen PU, Bräckow J. Electrostatic bubbles and supramolecular assistance of photosensitization by carboxylated Ru (II) complexes. J Am Chem Soc. 2003;125(16):4894-4906.
38. Guerrero-Martínez A, Pérez-Juste J, Liz-Marzán LM. Recent progress on silica coating of nanoparticles and related nanomaterials. Adv Mater Deerfield. 2010;22(11):1182-1195.
39. Fernandez JM, Bilgin MD, Grossweiner LI. Singlet oxygen generation by photodynamic agents. J Photochem Photobiol B. 1997;37(1-2): 131-140.
40. Rotomskis R, Valanciunaite J, Skripka A, et al. Complexes of functionalized quantum dots and chlorin e6 in photodynamic therapy. Lith J Phys. 2013;53(1):57-68.
41. XIA O, Boudreau MD, Zhou Y-T, Yin J-J, Fu PP. UVB photoirradiation of aloe vera formation of free radicals, singlet oxygen, superoxide, and induction of lipid peroxidation. J Food Drug Anal. 2011;19(4): 165-175.
42. Davies MJ. Singlet oxygen-mediated damage to proteins and its consequences. Biochem Biophys Res Commun. 2003;305(3):761-770.
43. Cadet J, Ravanat JL, Martinez GR, Medeiros MHG, Mascio PD. Singlet oxygen oxidation of isolated and cellular DNA: product formation and mechanistic insights. Photochem Photobiol. 2006;82(5):1219-1225.
44. Agnez-Lima LF, Melo JT, Silva AE, et al. DNA damage by singlet oxygen and cellular protective mechanisms. Mutat Res. 2012;751(1): 15-28.
45. Jarvi MT, Niedre MJ, Patterson MS, Wilson BC. The influence of oxygen depletion and photosensitizer triplet-state dynamics during photodynamic therapy on accurate singlet oxygen luminescence monitoring and analysis of treatment dose response. Photochem Photobiol. 2011;87(1):223-234.
46. Li Z, Zhang Y. An efficient and user-friendly method for the synthesis of hexagonal-phase NaYF 4:Yb, Er/Tm nanocrystals with controllable shape and upconversion fluorescence. Nanotechnology. 2008; 19(34):345606.
47. Li Z, Zhang Y, Jiang S. Multicolor core/shell-structured upconversion fluorescent nanoparticles. Adv Mater Deerfield. 2008;20(24): 4765-4769.
48. Beganskien ˙ A, Sirutkaitis V, Kurtinaitien M, Juškénas R, Kareiva A. FTIR, TEM and NMR investigations of Stöber silica nanoparticles. Mater Sci (Medžiagotyra). 2004;10:287-290.
49. Lewis IR, Daniel NW, Griffiths PR. Interpretation of Raman spectra of nitro-containing explosive materials. Part I: group frequency and structural class membership. Appl Spectrosc. 1997;51(12):1854-1867.
50. Zecchina A, Bordiga S, Spoto G, et al. Silicalite characterization. 2. IR spectroscopy of the inter0061ction of carbon monoxide with internal and external hydroxyl groups. J Phys Chem. 1992;96(12):4991-4997.
51. Lam AJ, St-Pierre F, Gong Y, et al. Improving FRET dynamic range with bright green and red fluorescent proteins. Nat Meth. 2012;9(10): 1005-1012.
52. Taraska JW, Puljung MC, Zagotta WN. Short-distance probes for protein backbone structure based on energy transfer between bimane and transition metal ions. Proc Natl Acad Sci U S A. 2009;106(38): 16227-16232.
53. Sivéry A, Barras A, Boukherroub R, et al. Production rate and reactivity of singlet oxygen 1O2(1Δg) directly photoactivated at 1270 nm in lipid nanocapsules dispersed in water. J Phys Chem. 2014;118(5): 2885-2893.
54. Krishna CM, Lion Y, Riesz P. A Study of 1O2 production by immoblilized sensitizer outside the solution. Measurement of 1O2 generation. Photochem Photobiol. 1987;45(1):1-6.
55. Krasnovsky AA Jr, Roumbal YV, Strizhakov AA. Rates of 1O2 (1Δg) production upon direct excitation of molecular oxygen by 1270 nm laser radiation in air-saturated alcohols and micellar aqueous dispersions. Chem Phys Lett. 2008;458(1-3):195-199.
56. Boyd V, Cholewa OM, Papas KK. Limitations in the use of fluorescein diacetate/propidium iodide (FDA/PI) and cell permeable nucleic acid stains for viability measurements of isolated islets of Langerhans. Curr Trends Biotechnol Pharm. 2008;2(2):66.
57. Gustafsson MG. Nonlinear structured-illumination microscopy: widefield fluorescence imaging with theoretically unlimited resolution. Proc Natl Acad Sci U S A. 2005;102(37):13081-13086.