Vascular risk factors and Alzheimer's disease

BMC Medicine

Volumn 12, Issue 1, 2014, Pages

  O'Brien, John T ^a   Markus, Hugh S ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Alzheimer's disease; Dementia; Hypertension; Prevention; Risk factors; Stroke; Treatment; Vascular risk

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; CARDIOVASCULAR RISK; COGNITIVE DEFECT; DISEASE ASSOCIATION; DISEASE COURSE; HUMAN; MULTIINFARCT DEMENTIA; VASCULAR DISEASE; CARDIOVASCULAR DISEASES; PATHOPHYSIOLOGY; RISK FACTOR; STROKE;

ALZHEIMER DISEASE; CARDIOVASCULAR DISEASES; HUMANS; RISK FACTORS; STROKE;

EID: 84920843761     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-014-0218-y     Document Type: Article

References (17)

1. Ballard C, Gauthier S, Corbett A, Brayne C, Aarsland D, Jones E: Alzheimer's disease. Lancet 2011, 377:1019-1031.
2. Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR: Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med 2014, 370:322-333.
3. Tosto G, Reitz C: Genome-wide association studies in Alzheimer's disease: a review. Curr Neurol Neurosci Rep 2013, 13:1-7.
4. O'Brien JT, Erkinjuntti T, Reisberg B, Roman G, Sawada T, Pantoni L, Bowler JV, Ballard C, DeCarli C, Gorelick PB, Rockwood K, Burns A, Gauthier S, DeKosky ST: Vascular cognitive impairment. Lancet Neurol 2003, 2:89-98.
5. Snowdon DA, Greiner LH, Mortimer JA, Riley KP, Greiner PA, Markesbery WR: Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA 1997, 277:813-817.
6. Toledo JB, Arnold SE, Raible K, Brettschneider J, Xie SX, Grossman M, Monsell SE, Kukull WA, Trojanowski JQ: Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's coordinating centre. Brain 2013, 136:2697-2706.
7. Petrovitch H, White LR, Izmirilian G, Ross GW, Havlik RJ, Markesbery W, Nelson J, Davis DG, Launer LJ: Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death: the HAAS. Honolulu-Asia Aging Study. Neurobiol Aging 2000, 21:57-62.
8. Weller RO, Preston SD, Subash M, Carare RO: Cerebral amyloid angiopathy in the aetiology and immunotherapy of Alzheimer disease. Alzheimers Res Ther 2009, 1:6.
9. Jellinger KA, Attems J: The overlap between vascular disease and Alzheimer's disease - lessons from pathology. BMC Med 2014, 12:206.
10. de Bruijn RF, Ikram MA: Cardiovascular risk factors and future Alzheimer's disease risk. BMC Med 2014, 12:130.
11. Wardlaw JM, Smith EE, Biessels GJ, Cordonnier C, Fazekas F, Frayne R, Lindley RI, O'Brien JT, Barkhof F, Benavente OR, Black SE, Brayne C, Breteler M, Chabriat H, DeCarli C, de Leeuw FE, Doubal F, Duering M, Fox NC, Greenberg S, Hachinski V, Kilimann I, Mok V, van Oostenbrugge R, Pantoni L, Speck O, Stephan BC, Teipel S, Viswanathan A, Werring D, Chen C, Smith C, van Buchem M, Norrving B, Gorelick PB, Dichgans M: Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol 2013, 12:822-838.
12. Smith AD, Smith SM, De Jager CA, Whitbread P, Johnston C, Agacinski G, Oulhaj A, Bradley KM, Jacoby R, Refsum H: Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial. PLoS One 2010, 5:e12244.
13. Valenti R, Pantoni L, Markus HS: Treatment of vascular risk factors in patients with a diagnosis of Alzheimer disease; a systematic review. BMC Med 2014, 12:160.
14. Peters R, Beckett N, Forette F, Tuomilehto J, Clarke R, Ritchie C, Waldman A, Walton I, Poulter R, Ma S, Comsa M, Burch L, Fletcher A, Bulpitt C: Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial. Lancet Neurol 2008, 7:683-689.
15. Richard E, Kuiper R, Dijkgraaf M, Van Gool WA: Vascular care in patients with Alzheimer's disease with cerebrovascular lesions-a randomized clinical trial. J Am Geriatr Soc 2009, 57:797-805.
16. Feldman HH, Doody RS, Kivipelto M, Sparks DL, Waters DD, Jones RW, Schwam E, Schindler R, Hey-Hadavi J, DeMicco DA, Breazna A, LEADe Investigators: Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe. Neurology 2010, 74:956-964.
17. O'Brien JT, Burns A, The BAP, Dementia Consensus Group: Clinical practice with anti-dementia drugs: a revised (second) consensus statement from the British Association for Psychopharmacology. J Psychopharmacol 2011, 25:997-1019.