Light-responsive nanoparticle depot to control release of a small molecule angiogenesis inhibitor in the posterior segment of the eye

Journal of Controlled Release

Volumn 200, Issue , 2015, Pages 71-77

  Huu, Viet Anh Nguyen ^a,e   Luo, Jing ^c   Zhu, Jie ^c   Zhu, Jing ^c   Patel, Sherrina ^c   Boone, Alexander ^d   Mahmoud, Enas ^b   McFearin, Cathryn ^b   Olejniczak, Jason ^e   De Gracia Lux, Caroline ^b   Lux, Jacques ^b   Fomina, Nadezda ^b   Huynh, Michelle ^e   Zhang, Kang ^c,e   Almutairi, Adah ^a,b,e  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anti angiogenic; Light triggered; Nanoparticle; Ocular; Polymer; Triggered release

Indexed keywords

BIOCOMPATIBILITY; EYE PROTECTION; MOLECULES; NANOPARTICLES; NONINVASIVE MEDICAL PROCEDURES; OPHTHALMOLOGY; POLYMERS; TARGETED DRUG DELIVERY;

ANGIOGENESIS INHIBITORS; ANTI-ANGIOGENIC; CHOROIDAL NEOVASCULARIZATION; INTRAVITREAL INJECTION; OCULAR; ON-DEMAND DRUG DELIVERY; TRIGGERED DRUG RELEASE; TRIGGERED RELEASE;

CONTROLLED DRUG DELIVERY;

NANOPARTICLE; NINTEDANIB; ANGIOGENESIS INHIBITOR; DELAYED RELEASE FORMULATION; INDOLE DERIVATIVE; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG DELIVERY SYSTEM; DRUG RELEASE; ELECTRORETINOGRAM; IN VIVO STUDY; IRRADIATION; MALE; NONHUMAN; OPTICAL TOMOGRAPHY; PRIORITY JOURNAL; RAT; SUBRETINAL NEOVASCULARIZATION; ULTRAVIOLET RADIATION; ADMINISTRATION AND DOSAGE; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DELAYED RELEASE FORMULATION; EYE; LIGHT; METABOLISM; MOUSE; RADIATION RESPONSE; SPRAGUE DAWLEY RAT;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL LINE; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; EYE; INDOLES; LACTIC ACID; LIGHT; MALE; MICE; NANOPARTICLES; POLYGLYCOLIC ACID; RATS, SPRAGUE-DAWLEY;

EID: 84920747606     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.01.001     Document Type: Article

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