A novel collagen-nanohydroxyapatite microRNA-activated scaffold for tissue engineering applications capable of efficient delivery of both miR-mimics and antagomiRs to human mesenchymal stem cells

Journal of Controlled Release

Volumn 200, Issue , 2015, Pages 42-51

  Castaño, Irene Mencía ^a,b   Curtin, Caroline M ^a,b   Shaw, Georgina ^c   Mary Murphy, J ^c   Duffy, Garry P ^a,b   O'Brien, Fergal J ^a,b  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Collagen based scaffolds; Human mesenchymal stem cells; MicroRNA; Nanohydroxyapatite particles; Tissue engineering

Indexed keywords

CELL CULTURE; CELL ENGINEERING; CELLS; COLLAGEN; CYTOLOGY; GENE EXPRESSION; MONOLAYERS; SCAFFOLDS (BIOLOGY); STEM CELLS; TISSUE; TISSUE ENGINEERING;

CLINICAL TRANSLATION; COLLAGEN-BASED SCAFFOLDS; HUMAN MESENCHYMAL STEM CELLS; HUMAN MESENCHYMAL STEM CELLS (HMSCS); MICRORNAS; NANO-HYDROXYAPATITE; THERAPEUTIC APPLICATION; TISSUE ENGINEERING APPLICATIONS;

RNA;

ANTAGOMIR; COLLAGEN; COLLAGEN NANOHYDROXYAPATITE SCAFFOLD; HYDROXYAPATITE; MICRORNA; MOLECULAR SCAFFOLD; UNCLASSIFIED DRUG; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE (NADP); NANO-HYDROXYAPATITE-COLLAGEN;

ARTICLE; BONE REMODELING; CELL PROLIFERATION; CELL VIABILITY; CELLS BY BODY ANATOMY; DRUG CYTOTOXICITY; GENE CONTROL; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTERNALIZATION; MESENCHYMAL STEM CELL; MONOLAYER CULTURE; NONVIRAL GENE THERAPY; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; RNA INTERFERENCE; SURFACE CHARGE; TISSUE ENGINEERING; CELL CULTURE; CELL SURVIVAL; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; TISSUE SCAFFOLD;

CELL SURVIVAL; CELLS, CULTURED; COLLAGEN; DURAPATITE; GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (NADP+); HUMANS; MESENCHYMAL STROMAL CELLS; MICRORNAS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84920742524     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.12.034     Document Type: Article

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