Baseline choroidal thickness as a predictor for response to anti-vascular endothelial growth factor therapy in diabetic macular edema

American Journal of Ophthalmology

Volumn 159, Issue 1, 2015, Pages 85-91.e3

  Rayess, Nadim ^a   Rahimy, Ehsan ^a   Ying, Gui Shuang ^b   Bagheri, Nika ^a   Ho, Allen C ^a   Regillo, Carl D ^a   Vander, James F ^a   Hsu, Jason ^a  

^a WILLS EYE HOSPITAL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; RANIBIZUMAB; ANGIOGENESIS INHIBITOR; MONOCLONAL ANTIBODY; VASCULOTROPIN A;

ADULT; AGED; ARTICLE; CENTRAL MACULAR THICKNESS; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC MACULAR EDEMA; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HUMAN; MALE; MEDICAL RECORD REVIEW; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SHORT COURSE THERAPY; SUBFOVEAL CHOROIDAL THICKNESS; TREATMENT RESPONSE; VISUAL ACUITY; VISUAL SYSTEM PARAMETERS; ANTAGONISTS AND INHIBITORS; CHOROID; DIABETIC RETINOPATHY; INTRAVITREAL DRUG ADMINISTRATION; MACULAR EDEMA; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY; PREDICTIVE VALUE; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL, HUMANIZED; CHOROID; DIABETIC RETINOPATHY; FEMALE; HUMANS; INTRAVITREAL INJECTIONS; MACULAR EDEMA; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VISUAL ACUITY; YOUNG ADULT;

EID: 84920662682     PISSN: 00029394     EISSN: 18791891     Source Type: Journal    
DOI: 10.1016/j.ajo.2014.09.033     Document Type: Article

References (18)

1. P. Romero-Aroca Managing diabetic macular edema: the leading cause of diabetes blindness World J Diabetes 2 6 2011 98 104
2. G. Querques, R. Lattanzio, and L. Querques Enhanced depth imaging optical coherence tomography in type 2 diabetes Invest Ophthalmol Vis Sci 53 10 2012 6017 6024
3. I. Lains, J. Figueira, and A.R. Santos Choroidal thickness in diabetic retinopathy: the influence of antianiogenic therapy Retina 34 6 2014 1199 1207
4. M. Adhi, E. Brewer, N.K. Waheed, and J.S. Duker Analysis of morphological features and vascular layers of choroid in diabetic retinopathy using spectral-domain optical coherence tomography JAMA Ophthalmol 131 10 2013 1267 1274
5. C.V. Regatieri, L. Branchini, J. Carmody, J.G. Fujimoto, and J.S. Duker Choroidal thickness in patients with diabetic retinopathy analyzed by spectral-domain optical coherence tomography Retina 32 3 2012 563 568
6. Early Treatment Diabetic Retinopathy Study design and baseline patient characteristics. ETDRS report number 7 Ophthalmology 98 5 Suppl 1991 741 756
7. D.L. Nickla, and J. Wallman The multifunctional choroid Prog Retin Eye Res 29 2 2010 144 168
8. A.A. Hidayat, and B.S. Fine Diabetic choroidopathy. Light and electron microscopic observations of seven cases Ophthalmology 92 4 1985 512 522
9. G.A. Lutty, J. Cao, and D.S. McLeod Relationship of polymorphonuclear leukocytes to capillary dropout in the human diabetic choroid Am J Pathol 151 3 1997 707 714
10. M.E. Langham, R. Grebe, S. Hopkins, S. Marcus, and M. Sebag Choroidal blood flow in diabetic retinopathy Exp Eye Res 52 2 1991 167 173
11. L.S. Schocket, A.J. Brucker, R.M. Niknam, J.E. Grunwald, J. DuPont, and A.J. Brucker Foveolar choroidal hemodynamics in proliferative diabetic retinopathy Int Ophthalmol 25 2 2004 89 94
12. F. Mori, T. Hikichi, J. Takahashi, T. Nagaoka, and A. Yoshida Dysfunction of active transport of blood-retinal barrier in patients with clinically significant macular edema in type 2 diabetes Diabetes Care 25 7 2002 1248 1249
13. S.A. Vinores, A.I. Youssri, and J.D. Luna Upregulation of vascular endothelial growth factor in ischemic and non-ischemic human and experimental retinal disease Histol Histopathol 12 1 1997 99 109
14. L.P. Aiello, J.M. Northrup, B.A. Keyt, H. Takagi, and M.A. Iwamoto Hypoxic regulation of vascular endothelial growth factor in retinal cells Arch Ophthalmol 113 12 1995 1538 1544
15. H.M. Kang, H.J. Kwon, J.H. Yi, C.S. Lee, and S.C. Lee Subfoveal choroidal thickness as a potential predictor of visual outcome and treatment response after intravitreal ranibizumab injections for typical exudative age-related macular degeneration Am J Ophthalmol 157 5 2014 1013 1021
16. J.T. Kim, D.H. Lee, S.G. Joe, J.G. Kim, and Y.H. Yoon Changes in choroidal thickness in relation to the severity of retinopathy and macular edema in type 2 diabetic patients Invest Ophthalmol Vis Sci 54 5 2013 3378 3384
17. A.S. Maharaj, and P.A. D'Amore Roles for VEGF in the adult Microvasc Res 74 2-3 2007 100 113
18. G. Yiu, V. Manjunath, S.J. Chiu, S. Farsiu, and T.H. Mahmoud Effect of anti-vascular endothelial growth factor therapy on choroidal thickness in diabetic macular edema Am J Ophthalmol 158 4 2014 745 751