Randomized evaluation of live attenuated vs. inactivated influenza vaccines in schools (RELATIVES) pilot study: A cluster randomized trial

Vaccine

Volumn 33, Issue 4, 2015, Pages 535-541

  Kwong, Jeffrey C ^a,b,c,d,e,k   Pereira, Jennifer A ^a   Quach, Susan ^a,k   Pellizzari, Rosana ^f   Dusome, Edwina ^f   Russell, Margaret L ^g,k   Hamid, Jemila S ^h,i   Feinberg, Yael ^a   Winter, Anne Luise ^a   Gubbay, Jonathan B ^a,b,d   Sirtonski, Brittany ^a   Moher, Deanna ^a   Sider, Doug ^a   Finkelstein, Michael ^b,j   Loeb, Mark ^h   Bettinger, Julie ^k   Buckeridge, David ^k   Hamid, Jemila ^k   Crowcroft, Natasha ^k   Deeks, Shelley ^k   Guay, Maryse ^k   McGeer, Allison ^k   Pereira, Jennifer ^k   Quan, Sherman ^k   more..

^a PUBLIC HEALTH ONTARIO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c INSTITUTE FOR CLINICAL EVALUATIVE SCIENCES   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY HEALTH NETWORK   (Canada)

^f Peterborough County City Health Unit   (Canada)

^g UNIVERSITY OF CALGARY   (Canada)

^h MCMASTER UNIVERSITY   (Canada)

ⁱ ST MICHAEL'S HOSPITAL   (Canada)

^j TORONTO PUBLIC HEALTH   (Canada)

^k NONE

more..

Author keywords

Canada; Immunization Programs; Influenza; Ontario; Parents; Schools

Indexed keywords

INACTIVATED INFLUENZA VACCINE; INFLUENZA VACCINE; UNCLASSIFIED DRUG; INACTIVATED VACCINE; LIVE VACCINE;

ARTICLE; BODY MASS; CANADA; CHILD; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DRUG COST; DRUG EFFICACY; DRUG SAFETY; DRUG UPTAKE; FEMALE; FOLLOW UP; HUMAN; INFLUENZA; INFLUENZA VACCINATION; LONG TERM CARE; MALE; PILOT STUDY; PREVENTIVE HEALTH SERVICE; PRIMARY SCHOOL; PROGRAM ACCEPTABILITY; PROGRAM EVALUATION; RANDOMIZED CONTROLLED TRIAL; RURAL POPULATION; SCHOOL CHILD; SINGLE DRUG DOSE; TELEPHONE INTERVIEW; UNSPECIFIED SIDE EFFECT; URBAN POPULATION; ADOLESCENT; HEALTH CARE COST; IMMUNOLOGY; INFLUENZA, HUMAN; INTERVIEW; PATIENT ATTITUDE; PRESCHOOL CHILD; PROCEDURES; QUESTIONNAIRE; SCHOOL; STUDENT; UTILIZATION; VACCINATION;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; FEMALE; HEALTH CARE COSTS; HUMANS; INFLUENZA VACCINES; INFLUENZA, HUMAN; INTERVIEWS AS TOPIC; MALE; ONTARIO; PATIENT ACCEPTANCE OF HEALTH CARE; PILOT PROJECTS; QUESTIONNAIRES; SCHOOLS; STUDENTS; VACCINATION; VACCINES, ATTENUATED; VACCINES, INACTIVATED;

EID: 84920620299     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.11.044     Document Type: Article

References (28)

1. Schanzer D.L., Sevenhuysen C., Winchester B., Mersereau T. Estimating influenza deaths in Canada, 1992-2009. PLoS One 2013, 8(11):e80481.
2. Schanzer D.L., Schwartz B. Impact of seasonal and pandemic influenza on emergency department visits, 2003-2010, Ontario, Canada. Acad Emerg Med 2013, 20(4):388-397.
3. Schanzer D.L., Zheng H., Gilmore J. Statistical estimates of absenteeism attributable to seasonal and pandemic influenza from the Canadian Labour Force Survey. BMC Infect Dis 2011, 11(90). (2334-11-90).
4. Schanzer D.L., Langley J.M., Tam T.W. Role of influenza and other respiratory viruses in admissions of adults to Canadian hospitals. Influenza Other Respir Viruses 2008, 2(1):1-8.
5. Schanzer D.L., Langley J.M., Tam T.W. Hospitalization attributable to influenza and other viral respiratory illnesses in Canadian children. Pediatr Infect Dis J 2006, 25(9):795-800.
6. Kwong J.C., Stukel T.A., Lim J., McGeer A.J., Upshur R.E., Johansen H., et al. The effect of universal influenza immunization on mortality and health care use. PLoS Med 2008, 5(10):e211.
7. Baguelin M., Flasche S., Camacho A., Demiris N., Miller E., Edmunds W.J. Assessing optimal target populations for influenza vaccination programmes: an evidence synthesis and modelling study. PLoS Med 2013, 10(10):e1001527.
8. Loeb M., Russell M.L., Moss L., Fonseca K., Fox J., Earn D.J., et al. Effect of influenza vaccination of children on infection rates in Hutterite communities: a randomized trial. JAMA 2010, 303(10):943-950.
9. Pebody R.G., Green H.K., Andrews N., Zhao H., Boddington N., Bawa Z., et al. Uptake and impact of a new live attenuated influenza vaccine programme in England: early results of a pilot in primary school-age children, 2013/14 influenza season. Euro Surveill 2014, 19(22):20823.
10. Moran K., Maaten S., Guttmann A., Northrup D., Kwong J.C. Influenza vaccination rates in Ontario children: implications for universal childhood vaccination policy. Vaccine 2009, 27(17):2350-2355.
11. Kwong J.C., Ge H., Rosella L.C., Guan J., Maaten S., Moran K., et al. School-based influenza vaccine delivery, vaccination rates, and healthcare use in the context of a universal influenza immunization program: an ecological study. Vaccine 2010, 28(15):2722-2729.
12. National Vaccine Advisory Committee The promise and challenge of adolescent immunization. Am J Prev Med 2008, 35(2):152-157.
13. Sales J.M., Painter J.E., Pazol K., Gargano L.M., Orenstein W., Hughes J.M., et al. Rural parents' vaccination-related attitudes and intention to vaccinate middle and high school children against influenza following educational influenza vaccination intervention. Hum Vaccin 2011, 7(11):1146-1152.
14. Painter J.E., Sales J.M., Pazol K., Wingood G.M., Windle M., Orenstein W.A., et al. Adolescent attitudes toward influenza vaccination and vaccine uptake in a school-based influenza vaccination intervention: a mediation analysis. J Sch Health 2011, 81(6):304-312.
15. Ontario Ministry of Health and Long-Term Care Immunization: school age children 2014, Ontario Ministry of Health and Long-Term Care, Ontario, 〈http://www.health.gov.on.ca/en/public/programs/immunization/school_age.aspx〉 (accessed 2014 Sep 8).
16. MacDougall D., Crowe L., Pereira J.A., Kwong J.C., Quach S., Wormsbecker A.E., et al. Parental perceptions of school-based influenza immunisation in Ontario, Canada: a qualitative study. BMJ Open 2014, 4(6):e005189. (2014-005189).
17. National Advisory Committee on Immunization (NACI) Statement on seasonal influenza vaccine for 2011-2012. Can Commun Dis Rep 2011, 37(ACS-5):1-55.
18. Rhorer J., Ambrose C.S., Dickinson S., Hamilton H., Oleka N.A., Malinoski F.J., et al. Efficacy of live attenuated influenza vaccine in children: a meta-analysis of nine randomized clinical trials. Vaccine 2009, 27(7):1101-1110.
19. Poehling K.A., Talbot H.K., Williams J.V., Zhu Y., Lott J., Patterson L., et al. Impact of a school-based influenza immunization program on disease burden: comparison of two Tennessee counties. Vaccine 2009, 27(20):2695-2700.
20. du Plessis V., Beshiri R., Bollman R. Definitions of rural. Rural Small-Town Can. Anal. Bull. 2001, 3(3):1-17.
21. Bland J.M., Kerry S.M. Statistics notes. Weighted comparison of means. BMJ 1998, 316(7125):129.
22. Guest G., MacQueen K.M., Namey E.E. Applied thematic analysis 2012, Sage Publications Inc., Thousand Oaks, CA.
23. King J.C., Stoddard J.J., Gaglani M.J., Moore K.A., Magder L., McClure E., et al. Effectiveness of school-based influenza vaccination. N Engl J Med 2006, 355(24):2523-2532.
24. Tarride J.E., Burke N., Von Keyserlingk C., O'Reilly D., Xie F., Goeree R. Cost-effectiveness analysis of intranasal live attenuated vaccine (LAIV) versus injectable inactivated influenza vaccine (TIV) for Canadian children and adolescents. Clinicoecon Outcomes Res 2012, 4:287-298.
25. Rose M.A., Stoermann J., Bittner-Brewe J., Rosewich M., Eickmeier O., et al. Effectiveness, tolerability and patient satisfaction of paediatric live-attenuated influenza immunization (LAIV) in routine-care in Germany: a case-control study. Trials Vaccinol 2013, 2:49-52.
26. Flood E.M., Ryan K.J., Rousculp M.D., Beusterien K.M., Block S.L., Hall M.C., et al. A survey of children's preferences for influenza vaccine attributes. Vaccine 2011, 29(26):4334-4340.
27. Ambrose C.S., Sifakis F. Factors associated with increased vaccination in 2009 H1N1 school-located influenza vaccination programs. Hum Vaccin 2011, 7(8):864-867.
28. Lind C., Russell M.L., MacDonald J., Collins R., Frank C.J., Davis A.E. School-based influenza vaccination: parents' perspectives. PLoS One 2014, 9(3):e93490.