Deubiquitinase OTUD5 mediates the sequential activation of PDCD5 and p53 in response to genotoxic stress

Cancer Letters

Volumn 357, Issue 1, 2015, Pages 419-427

  Park, Soo Yeon ^a   Choi, Hyo Kyoung ^a   Choi, Youngsok ^b   Kwak, Sungmin ^c   Choi, Kyung Chul ^c   Yoon, Ho Geun ^a  

^a Yonsei University College of Medicine   (South Korea)

^b CHA University   (South Korea)

^c University of Ulsan College of Medicine   (South Korea)

Author keywords

Cell death; Genotoxic stress response; OTUD5; P53; PDCD5

Indexed keywords

DEUBIQUITINASE; ETOPOSIDE; LYSINE; MEMBRANE RECEPTOR; OTU DEUBIQUITINASE 5; PROGRAMMED DEATH 5 RECEPTOR; PROTEIN P53; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; DEUBIQUITINATING ENZYME A, HUMAN; PDCD5 PROTEIN, HUMAN; PROTEINASE; TP53 PROTEIN, HUMAN; TUMOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; EMBRYO; GENE SILENCING; GENOTOXICITY; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; ANIMAL; COLORECTAL NEOPLASMS; DNA DAMAGE; GENETIC TRANSFECTION; GENETICS; HCT116 CELL LINE; LUNG NEOPLASMS; METABOLISM; PHYSIOLOGICAL STRESS; PHYSIOLOGY; TRANSCRIPTION INITIATION; TUMOR CELL LINE; UBIQUITINATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA DAMAGE; ENDOPEPTIDASES; ETOPOSIDE; GENE KNOCKDOWN TECHNIQUES; HCT116 CELLS; HUMANS; LUNG NEOPLASMS; MICE; NEOPLASM PROTEINS; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINATION;

EID: 84920613451     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.12.005     Document Type: Article

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