Kinetics of iron import into developing mouse organs determined by a pup-swapping method

Journal of Biological Chemistry

Volumn 290, Issue 1, 2015, Pages 520-528

  Chakrabarti, Mrinmoy ^a   Barlas, Mirza Nofil ^b   McCormick, Sean P ^a   Lindahl, Lora S ^a   Lindahl, Paul A ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF THE SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; ISOTOPES; KINETICS; LIQUID CHROMATOGRAPHY; MAMMALS;

BLOOD PLASMA; DIETARY IRONS; IRON SPECIES; IRON-CONTAINING; MODEL FITTING; MOSSBAUER;

IRON;

FERRITIN; HEMOPEXIN; IRON; TRANSFERRIN; IRON INTAKE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FEMALE; IRON TRANSPORT; LIQUID CHROMATOGRAPHY; MALE; MATHEMATICAL MODEL; MOUSE; NEWBORN; NONHUMAN; ORGANOGENESIS; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; TISSUE LEVEL; TRANSPORT KINETICS; ANIMAL; ATOMIC ABSORPTION SPECTROMETRY; BRAIN; CARDIAC MUSCLE; CHEMISTRY; ION TRANSPORT; IRON INTAKE; KIDNEY; KINETICS; LIVER; METABOLISM; ORGAN SIZE; PHARMACOKINETICS; PHYSIOLOGY; SPLEEN; STATISTICAL MODEL;

MUS;

ANIMALS; ANIMALS, NEWBORN; BRAIN; FEMALE; FERRITINS; ION TRANSPORT; IRON ISOTOPES; IRON, DIETARY; KIDNEY; KINETICS; LIVER; MALE; MICE; MODELS, STATISTICAL; MYOCARDIUM; ORGAN SIZE; ORGANOGENESIS; SPECTROPHOTOMETRY, ATOMIC; SPLEEN; TRANSFERRIN;

EID: 84920517373     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.606731     Document Type: Article

References (36)

1. Ganz, T. (2013) Systemic iron homeostasis. Physiol. Rev. 93, 1721-1741
2. Stankiewicz, J., Panter, S. S., Neema, M., Arora, A., Batt, C. E., and Bakshi, R. (2007) Iron in chronic brain disorders: Imaging and neurotherapeutic implications. Neurotherapeutics 4, 371-386
3. Erikson, K. M., Pinero, D. J., Connor, J. R., and Beard, J. L. (1997) Regional brain iron, ferritin and transferrin concentrations during iron deficiency and iron repletion in developing rats. J. Nutr. 127, 2030-2038
4. Siimes, M. A., Refino C., and Dallman P. R. (1980) Physiological anemia of early development in the rat - characterization of the iron-responsive component. Am. J. Clin. Nutr. 33, 2601-2608
5. Holmes-Hampton, G. P., Chakrabarti M., Cockrell, A. L., McCormick, S. P., Abbott L. C., Lindahl L. S., and Lindahl, P. A. (2012) Changing iron content of the mouse brain during development. Metallomics 4, 761-770
6. Meynard D., Babitt, J. L., and Lin, H. Y. (2014) The liver: conductor of systemic iron balance. Blood 123, 168-176
7. D'Anna, M. C., Giogi, G., and Roque, M. E. (2011) Immunohistochemical studies on duodenum, spleen and liver in mice: distribution of ferroportin (FPN) and prohepcidin in an inflammation model. Int. J. Morphol. 29, 747-753
8. Ganz, T. (2012) Macrophages and systemic iron homeostasis. J. Innate Immun. 4, 446-453
9. Brissot, P., Ropert, M., Le Lan, C., and Loréal, O. (2012) Non-transferrin bound iron: A key role in iron overload and iron toxicity. Biochim. Biophys. Acta 1820, 403-410
10. Taylor, E. M., and Morgan, E. H. (1990) Developmental changes in transferrin and iron uptake by the brain in the rat. Brain Res. Dev. Brain Res. 55, 35-42
11. 59Fe uptake into brain and CSF and the influence thereon of antibodies against the transferrin receptor. J. Neurochem. 60, 106-113
12. Wright, T. L., Brissot, P., Ma, W. L., and Weisiger, R. A. (1986) Characterization of nontransferrin-bound iron clearance by rat liver. J. Biol. Chem. 261, 10909-10914
13. Craven, C. M., Alexander, J., Eldridge, M., Kushner, J. P., Bernstein, S., and Kaplan, J. (1987) Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis. Proc. Natl. Acad. Sci. U.S.A. 84, 3457-3461
14. Grebe, M., Pröfrock, D., Kakuschke, A., Broekaert, J. A., and Prange, A. (2011) Absolute quantification of transferrin in blood samples of harbor seals using HPLC-ICP-MS. Metallomics 3, 176-185
15. 59Fe-labeled transferrin for ferrokinetic studies. J. Clin. Pathol. 24, 472-474
16. Parkes, J. G., Randell, E. W., Olivieri, N. F., and Templeton, D. M. (1995) Modulation by iron loading and chelation of the uptake of non-transferrin-bound iron by human liver cells. Biochim. Biophys. Acta 1243, 373-380
17. Hider, R. C. (2002) Nature of nontransferrin-bound iron. Eur. J. Clin. Invest. 32, 50-54
18. Evans, R. W., Rafique, R., Zarea, A., Rapisarda, C., Cammack, R., Evans, P. J., Porter, J. B., and Hider, R. C. (2008) Nature of non-transferrin-bound iron: studies on iron citrate complexes and thalassemic sera. J. Biol. Inorg. Chem. 13, 57-74
19. Jacobs, E. M., Hendriks, J. C., van Tits, B. L., Evans, P. J., Breuer, W., Liu, D. Y., Jansen, E. H., Jauhiainen, K., Sturm, B., Porter, J. B., Scheiber-Mojdehkar, B., von Bonsdorff, L., Cabantchik, Z. I., Hider, R. C., and Swinkels, D. W. (2005) Results of an international round robin for the quantification of serum non-transferrin-bound iron: need for defining standardization and a clinically relevant isoform. Anal. Biochem. 341, 241-250
20. Simpson, R. J., Raja, K. B., Halliwell, B., Evans, P. J., Aruoma, O. I., Konijn, A. M., and Peters, T. J. (1991) Iron speciation in hypotransferrinaemic mouse serum. Biochem. Soc. Trans. 19, 317S
21. Grootveld, M., Bell, J. D., Halliwell, B., Aruoma, O. I., Bomford, A., and Sadler, P. J. (1989) Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis - characterization by high performance liquid chromatography and nuclear magnetic resonance spectroscopy. J. Biol. Chem. 264, 4417-4422
22. May, P. M., Linder, P. W., and Williams, D. R. (1977) Computer simulation of metal-ion equilibria in biofuels: models for low-molecular-weight complex distribution of calcium(II), magnesium(II), manganese(II), iron(III), copper(II), zinc(II) and lead(II) ions in human blood plasma. J. Chem. Soc. Dalton Trans. 6, 588-595
23. Link, G., Pinson, A., and Hershko, C. (1985) Heart cells in culture - a model of myocardial iron overload and chelation. J. Lab. Clin. Med. 106, 147-153
24. Liuzzi, J. P., Aydemir, F., Nam, H., Knutson, M. D., and Cousins, R. J. (2006) Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake in cells. Proc. Natl. Acad. Sci. U.S.A. 103, 13612-13617
25. Chen, T. T., Li, L., Chung, D. H., Allen, C. D., Torti, S. V., Torti, F. M., Cyster, J. G., Chen, C. Y., Brodsky, F. M., Niemi, E. C., Nakamura, M. C., Seaman, W. E., and Daws, M. R. (2005) Tim-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis. J. Exp. Med. 202, 955-965
26. Li, J. Y., Paragas, N., Ned, R. M., Qiu, A., Viltard, M., Leete, T., Drexler, I. R., Chen, X., Sanna-Cherchi, S., Mohammed, F., Williams, D., Lin, C. S., Schmidt-Ott, K. M., Andrews, N. C., and Barasch, J. (2009) Scara5 is a ferritin receptor mediating non-transferrin iron delivery. Dev. Cell 16, 35-46
27. Barisani, D., Berg, C. L., Wessling-Resnick, M., and Gollan, J. L. (1995) Evidence for a low Km transporter for non-transferrin-bound iron in isolated rat hepatocytes. Am. J. Physiol. 269, G570-G576
28. Dallman, P. R., and Spirito, R. A. (1977) Brain iron in the rat: Extremely slow turnover in normal rats may explain long-lasting effects on early iron deficiency. J. Nutr. 107, 1075-1081
29. 54Mn in mouse brain. J. Neurol. Sci. 170, 112-118
30. Beard, J. L., Wiesinger, J. A., Li, N., and Connor, J. R. (2005) Brain iron uptake in hypotransferrinemic mice: influence on systemic Fe status. J. Neurosci. Res. 79, 254-261
31. Pinilla-Tenas, J. J., Sparkman, B. K., Shawki, A., Illing, A. C., Mitchell, C. J., Zhao, N., Liuzzi, J. P., Cousins, R. J., Knutson, M. D., and Mackenzie, B. (2011) Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron. Am. J. Physiol. Cell Physiol. 301, C862-C871
32. 59Fe-distribution kinetics accordingly. Toxicology 241, 19-32
33. Gunji, H., Little, R. A., and Hiraiwa, K. (2002) Interleukine-6 deficiency increases blood volume without altering body composition in young mice. Cytokine 20, 30-37
34. Fernandez-Sanchez, M. L., St. Remy, R. R., Iglesias, H. G., Lopez-Sastre, J. B., Fernandez-Colomer, B., Perez-Solis, D., and Sanz-Medel, A. (2012) Iron content and its speciation in human milk from mothers of preterm and full-term infants at early stages of lactation: A comparison with commercial infant milk formulas. Microchem. J. 105, 108-114
35. Liao, Y., Jiang, R., and Lönnerdal, B. (2012) Biochemical and molecular impacts of lactoferrin on small intestinal growth and development during early life. Biochem. Cell Biol. 90, 476-484
36. Chen, J. H., Shahnavas, S., Singh, N., Ong, W. Y., and Walczyk, T. (2013) Stable iron isotope tracing reveals significant brain iron uptake in adult rats. Metallomics 5, 167-173