NDM-1 (New Delhi metallo beta lactamase-1) producing gram-negative bacilli: Emergence & clinical implications

Indian Journal of Medical Research

Volumn 140, Issue , 2014, Pages 672-678

  Fomda, Bashir Ahmad ^a   Khan, Asiya ^a   Zahoor, Danish ^a  

^a SHER I KASHMIR INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

BA MHT; BlaNDM 1; Combined disk test; MHT; MIC; OXA MHT

Indexed keywords

AMINOGLYCOSIDE; AZTREONAM; BETA LACTAM ANTIBIOTIC; BORONIC ACID DERIVATIVE; CARBAPENEM; CARBAPENEMASE; COTRIMOXAZOLE; IMIPENEM; LEVOFLOXACIN; METALLO BETA LACTAMASE; METALLO BETA LACTAMASE 1; OXACILLIN; POLYMYXIN B; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TETRACYCLINE; TIGECYCLINE; UNCLASSIFIED DRUG; BETA LACTAMASE; BETA-LACTAMASE NDM-1; CARBAPENEM DERIVATIVE;

ACINETOBACTER; ANTIBIOTIC SENSITIVITY; ARTICLE; CITROBACTER FREUNDII; DIAGNOSTIC TEST; DISK DIFFUSION; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MODIFIED HODGE TEST; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; SEQUENCE ANALYSIS; TERTIARY CARE CENTER; BIOSYNTHESIS; DRUG EFFECTS; ENZYMOLOGY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MULTIDRUG RESISTANCE;

ACINETOBACTER; BETA-LACTAMASES; CARBAPENEMS; CITROBACTER FREUNDII; DISK DIFFUSION ANTIMICROBIAL TESTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; GRAM-NEGATIVE BACTERIA; HUMANS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; TERTIARY CARE CENTERS;

EID: 84920413561     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Yong D, Toleman M A, Giske CG, Cho HS, Sundman K, Lee K, et al. Characterization of a new metallo-β-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob Agents Chemother 2009; 53: 5046-54.
2. Kumarasamy KK, Toleman MA, Walsh TR, Bagaria J, Butt F, Balakrishnan R, et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis 2010; 10: 597-602.
3. Moellering RC Jr. NDM-1 - a cause for worldwide concern. N Engl J Med 2010; 363: 2377-9.
4. Castanheira M, Deshpande LM, Mathai D, Bell JM, Jones RN, Mendes RE. Early dissemination of NDM-1- and OXA-181-producing Enterobacteriaceae in Indian hospitals: report from the SENTRY Antimicrobial Surveillance Program, 2006-2007. Antimicrob Agents Chemother 2011; 55: 1274-8.
5. Cornaglia G, Akova M, Amicosante g, Cantón R, Cauda R, Docquier JD, et al; ESCMID Study Group for Antimicrobial Resistance Surveillance (ESGARS). Metallo-β-lactamases as emerging resistance determinants in gram-negative pathogens: open issues. Int J Antimicrob Agents 2007; 29: 380-8.
6. Baur AW, Kirby WM, Sherris JC, Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol 1966; 45: 493-6.
7. Clinical and Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing, Twenty-First informational Supplement. CLSI document M100-S21. Wayne, PA: CLSI; 2011.
8. Lee K, Lim YS, Yong D, Yum JH, Chong Y. Evaluation of the Hodge test and the imipenem-EDTA double-disk synergy test for differentiating metallo- β-lactamase-producing isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol 2003; 41: 4623-9.
9. Miriagou V, Cornaglia G, Edelstein M, Galani I, Giske CG, gniadkowski M, et al. Acquired carbapenemases in gram-negative bacterial pathogens: detection and surveillance issues. Clin Microbiol Infect 2010; 16: 112-22.
10. Pasteran F, Mendez T, Rapoport M, guerriero L, Corso A. Controlling false-positive results obtained with the Hodge and Masuda assays for detection of class A carbapenemase in species of Enterobacteriaceae by incorporating boronic acid. J Clin Microbiol 2010; 48: 1323-32.
11. Franklin C, Liolios L, Peleg AY. Phenotypic detection of carbapenem susceptible metallo-β-lactamase producing Gram-negative bacilli in the clinical laboratory. J Clin Microbiol 2006; 44: 3139-44.
12. Nordmann P, Poirel L, Carrer A, Toleman MA, Walsh TR. How to detect NDM-1 producers. J Clin Microbiol 2011; 49: 718-21.
13. Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specifc gap penalties and weight matrix choice. Nucleic Acids Res 1994; 22: 4673-80.
14. Centers for Disease Control and Prevention (CDC). Detection of Enterobacteriaceae isolates carrying metallo-beta-lactamase-United States, 2010. MMWR Morb Mortal Wkly Rep 2010; 59: 750.
15. Poirel L, Al Maskari Z, Al Rashdi F, Bernabeu S, Nordmann P. NDM-1-producing Klebsiella pneumoniae isolated in the Sultanate of Oman. J Antimicrob Chemother 2011; 66: 304-6.
16. Poirel L, Lagrutta E, Taylor P, Pham J, Nordmann P. Emergence of metallo-beta-lactamase NDM-1-producing multidrug-resistant Escherichia coli in Australia. Antimicrob Agents Chemother 2010; 54: 4914-6.
17. Poirel L, Revathi G, Bernabeu S, Nordmann P. Detection of NDM-1-producing Klebsiella pneumoniae in Kenya. Antimicrob Agents Chemother 2011; 55: 934-6.
18. Poirel L, Ros A, Carricajo A, Berthelot P, Pozzetto B, Bernabeu S, et al. Extremely drug-resistant Citrobacter freundii isolate producing NDM-1 and other carbapenemases identifed in a patient returning from India. Antimicrob Agents Chemother 2011; 55: 447-8.
19. NDM-1 in Taiwan. J Chin Med Assoc 2010; 73: 596-8.
20. Rolain JM, Parola P, Cornaglia G. New Delhi metallo-beta-lactamase (NDM-1): towards a new pandemia? Clin Microbiol Infect 2010; 16: 1699-701.
21. Girlich D, Poirel L, Nordmann P. Value of the modifed Hodge test for detection of emerging carbapenemases in Enterobacteriaceae. J Clin Microbiol 2012; 50: 477-9.
22. Mochon AB, garner OB, Hindler JA, Krogstad P, Ward KW, Lewinski MA, et al. New Delhi metallo-β-lactamase (NDM-1)-producing Klebsiella pneumoniae: Case report and laboratory detection strategies. J Clin Microbiol 2011; 49: 1667-70.
23. Struelens MJ, Monnet DL, Magiorakos AP, O’Connor F, Giesecke J; European NDM-1 Survey Participants. New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae: emergence and response in Europe. Euro Surveill 2010; 15: 1-8.
24. Jovcic B, Lepsanovic Z, Suljagic V, Rackov G, Jelena Begovic J, Topisirovic L, et al. Emergence of NDM-1 metallo-β-lactamase in Pseudomonas aeruginosa clinical isolates from Serbia. Antimicrob Agents Chemother 2011; 55: 3929-31.
25. NDM-1 and armA in clinical isolates of Acinetobacter baumannii from India. J Antimicrob Chemother 2010; 65: 2253-4.
26. Peleg AY, Franklin C, Bell JM, Spelman DW. Dissemination of the metallo-β-lactamase gene WaMP_4 among gram-negative pathogens in a clinical setting in Australia. Clin Infect Dis 2005; 41: 1549-56.
27. Cornaglia G, Mazzariol A, Lauretti L, Rossolini GM, Fontana R. Hospital outbreak of carbapenem-resistant Pseudomonas aeruginosa producing VIM-1, a novel transferable metallo-β-lactamase. Clin Infect Dis 2000; 31: 1119-25.