-
1
-
-
84866597525
-
Allosteric post-translational modification codes
-
Nussinov, R., Tsai, C. J., Xin, F., and Radivojac, P. (2012) Allosteric post-translational modification codes. Trends Biochem. Sci. 37, 447-455
-
(2012)
Trends Biochem. Sci.
, vol.37
, pp. 447-455
-
-
Nussinov, R.1
Tsai, C.J.2
Xin, F.3
Radivojac, P.4
-
2
-
-
28044433451
-
Protein posttranslational modifications: The chemistry of proteome diversifications
-
Walsh, C. T., Garneau-Tsodikova, S., and Gatto, G. J., Jr. (2005) Protein posttranslational modifications: the chemistry of proteome diversifications. Angew Chem. Int. Ed. Engl. 44, 7342-7372
-
(2005)
Angew Chem. Int. Ed. Engl.
, vol.44
, pp. 7342-7372
-
-
Walsh, C.T.1
Garneau-Tsodikova, S.2
Gatto, G.J.3
-
3
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl, B. D., and Allis, C. D. (2000) The language of covalent histone modifications. Nature 403, 41-45
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
4
-
-
84876523828
-
DbPTM 3.0: An informative resource for investigating substrate site specificity and functional association of protein post-translational modifications
-
Lu, C. T., Huang, K. Y., Su, M. G., Lee, T. Y., Bretana, N. A., Chang, W. C., Chen, Y. J., Chen, Y. J., and Huang, H. D. (2013) DbPTM 3.0: an informative resource for investigating substrate site specificity and functional association of protein post-translational modifications. Nucleic Acids Res. 41, D295-D305
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D295-D305
-
-
Lu, C.T.1
Huang, K.Y.2
Su, M.G.3
Lee, T.Y.4
Bretana, N.A.5
Chang, W.C.6
Chen, Y.J.7
Chen, Y.J.8
Huang, H.D.9
-
5
-
-
84910679144
-
Proteome-wide post-translational modification statistics: Frequency analysis and curation of the swiss-prot database
-
Khoury, G. A., Baliban, R. C., and Floudas, C. A. (2011) Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database. Sci. Rep. 1, 90 DOI:10.1038/srep00090
-
(2011)
Sci. Rep.
, vol.1
, pp. 90
-
-
Khoury, G.A.1
Baliban, R.C.2
Floudas, C.A.3
-
6
-
-
83055173304
-
The first identification of lysine malonylation substrates and its regulatory enzyme
-
012658
-
Peng, C., Lu, Z., Xie, Z., Cheng, Z., Chen, Y., Tan, M., Luo, H., Zhang, Y., He, W., Yang, K., Zwaans, B. M., Tishkoff, D., Ho, L., Lombard, D., He, T. C., Dai, J., Verdin, E., Ye, Y., and Zhao, Y. (2011) The first identification of lysine malonylation substrates and its regulatory enzyme. Mol. Cell Proteomics 10, M111 012658
-
(2011)
Mol. Cell Proteomics
, vol.10
, pp. M111
-
-
Peng, C.1
Lu, Z.2
Xie, Z.3
Cheng, Z.4
Chen, Y.5
Tan, M.6
Luo, H.7
Zhang, Y.8
He, W.9
Yang, K.10
Zwaans, B.M.11
Tishkoff, D.12
Ho, L.13
Lombard, D.14
He, T.C.15
Dai, J.16
Verdin, E.17
Ye, Y.18
Zhao, Y.19
-
7
-
-
78650516004
-
Identification of lysine succinylation as a new post-translational modification
-
Zhang, Z., Tan, M., Xie, Z., Dai, L., Chen, Y., and Zhao, Y. (2011) Identification of lysine succinylation as a new post-translational modification. Nat. Chem. Biol. 7, 58-63
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 58-63
-
-
Zhang, Z.1
Tan, M.2
Xie, Z.3
Dai, L.4
Chen, Y.5
Zhao, Y.6
-
8
-
-
34248640428
-
Lysine propionylation and butyrylation are novel post-translational modifications in histones
-
Chen, Y., Sprung, R., Tang, Y., Ball, H., Sangras, B., Kim, S. C., Falck, J. R., Peng, J., Gu, W., and Zhao, Y. (2007) Lysine propionylation and butyrylation are novel post-translational modifications in histones. Mol. Cell Proteomics 6, 812-819
-
(2007)
Mol. Cell Proteomics
, vol.6
, pp. 812-819
-
-
Chen, Y.1
Sprung, R.2
Tang, Y.3
Ball, H.4
Sangras, B.5
Kim, S.C.6
Falck, J.R.7
Peng, J.8
Gu, W.9
Zhao, Y.10
-
9
-
-
59149086584
-
Molecular characterization of propionyllysines in nonhistone proteins
-
Cheng, Z., Tang, Y., Chen, Y., Kim, S., Liu, H., Li, S. S., Gu, W., and Zhao, Y. (2009) Molecular characterization of propionyllysines in nonhistone proteins. Mol. Cell Proteomics 8, 45-52
-
(2009)
Mol. Cell Proteomics
, vol.8
, pp. 45-52
-
-
Cheng, Z.1
Tang, Y.2
Chen, Y.3
Kim, S.4
Liu, H.5
Li, S.S.6
Gu, W.7
Zhao, Y.8
-
10
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan, M., Luo, H., Lee, S., Jin, F., Yang, J. S., Montellier, E., Buchou, T., Cheng, Z., Rousseaux, S., Rajagopal, N., Lu, Z., Ye, Z., Zhu, Q., Wysocka, J., Ye, Y., Khochbin, S., Ren, B., and Zhao, Y. (2011) Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 146, 1016-1028
-
(2011)
Cell
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
Luo, H.2
Lee, S.3
Jin, F.4
Yang, J.S.5
Montellier, E.6
Buchou, T.7
Cheng, Z.8
Rousseaux, S.9
Rajagopal, N.10
Lu, Z.11
Ye, Z.12
Zhu, Q.13
Wysocka, J.14
Ye, Y.15
Khochbin, S.16
Ren, B.17
Zhao, Y.18
-
11
-
-
84876518201
-
A chemical probe for lysine malonylation
-
Bao, X., Zhao, Q., Yang, T., Fung, Y. M., and Li, X. D. (2013) A chemical probe for lysine malonylation. Angew Chem. Int. Ed. Engl. 52, 4883-4886
-
(2013)
Angew Chem. Int. Ed. Engl.
, vol.52
, pp. 4883-4886
-
-
Bao, X.1
Zhao, Q.2
Yang, T.3
Fung, Y.M.4
Li, X.D.5
-
12
-
-
33749370466
-
Increased malonyl-coa levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects
-
Bandyopadhyay, G. K., Yu, J. G., Ofrecio, J., and Olefsky, J. M. (2006) Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. Diabetes 55, 2277-2285
-
(2006)
Diabetes
, vol.55
, pp. 2277-2285
-
-
Bandyopadhyay, G.K.1
Yu, J.G.2
Ofrecio, J.3
Olefsky, J.M.4
-
13
-
-
65049089643
-
Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-coa levels in the liver and skeletal muscle
-
Zhao, Z., Lee, Y. J., Kim, S. K., Kim, H. J., Shim, W. S., Ahn, C. W., Lee, H. C., Cha, B. S., and Ma, Z. A. (2009) Rosiglitazone and fenofibrate improve insulin sensitivity of pre-diabetic OLETF rats by reducing malonyl-CoA levels in the liver and skeletal muscle. Life Sci. 84, 688-695
-
(2009)
Life Sci.
, vol.84
, pp. 688-695
-
-
Zhao, Z.1
Lee, Y.J.2
Kim, S.K.3
Kim, H.J.4
Shim, W.S.5
Ahn, C.W.6
Lee, H.C.7
Cha, B.S.8
Ma, Z.A.9
-
14
-
-
2342509057
-
Hepatic expression of malonyl-coa decarboxylase reverses muscle, liver, and whole-animal insulin resistance
-
An, J., Muoio, D. M., Shiota, M., Fujimoto, Y., Cline, G. W., Shulman, G. I., Koves, T. R., Stevens, R., Millington, D., and Newgard, C. B. (2004) Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver, and whole-animal insulin resistance. Nat. Med. 10, 268-274
-
(2004)
Nat. Med.
, vol.10
, pp. 268-274
-
-
An, J.1
Muoio, D.M.2
Shiota, M.3
Fujimoto, Y.4
Cline, G.W.5
Shulman, G.I.6
Koves, T.R.7
Stevens, R.8
Millington, D.9
Newgard, C.B.10
-
15
-
-
84885392656
-
Chronic high glucose induced INS-1beta cell mito-chondrial dysfunction: A comparative mitochondrial proteome with SILAC
-
Chen, X., Cui, Z., Wei, S., Hou, J., Xie, Z., Peng, X., Li, J., Cai, T., Hang, H., and Yang, F. (2013) Chronic high glucose induced INS-1beta cell mito-chondrial dysfunction: a comparative mitochondrial proteome with SILAC. Proteomics 13, 3030-3039
-
(2013)
Proteomics
, vol.13
, pp. 3030-3039
-
-
Chen, X.1
Cui, Z.2
Wei, S.3
Hou, J.4
Xie, Z.5
Peng, X.6
Li, J.7
Cai, T.8
Hang, H.9
Yang, F.10
-
16
-
-
84876459715
-
Hydrogen peroxide impairs autophagic flux in a cell model of nonalcoholic fatty liver disease
-
Jiang, P., Huang, Z., Zhao, H., and Wei, T. (2013) Hydrogen peroxide impairs autophagic flux in a cell model of nonalcoholic fatty liver disease. Biochem. Biophys. Res. Commun. 433, 408-414
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.433
, pp. 408-414
-
-
Jiang, P.1
Huang, Z.2
Zhao, H.3
Wei, T.4
-
17
-
-
84885155285
-
Widespread and enzyme-independent nepsilon-acetylation and nepsilon-succinylation of proteins in the chemical conditions of the mitochondrial matrix
-
Wagner, G. R., and Payne, R. M. (2013) Widespread and enzyme-independent Nepsilon-acetylation and Nepsilon-succinylation of proteins in the chemical conditions of the mitochondrial matrix. J. Biol. Chem. 288, 29036-29045
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 29036-29045
-
-
Wagner, G.R.1
Payne, R.M.2
-
18
-
-
0034664941
-
Functional and molecular modeling studies of two hereditary fructose intolerance-causing mutations at arginine 303 in human liver aldolase
-
Santamaria, R., Esposito, G., Vitagliano, L., Race, V., Paglionico, I., Zancan, L., Zagari, A., and Salvatore, F. (2000) Functional and molecular modeling studies of two hereditary fructose intolerance-causing mutations at arginine 303 in human liver aldolase. Biochem. J. 350, 823-828
-
(2000)
Biochem. J.
, vol.350
, pp. 823-828
-
-
Santamaria, R.1
Esposito, G.2
Vitagliano, L.3
Race, V.4
Paglionico, I.5
Zancan, L.6
Zagari, A.7
Salvatore, F.8
-
19
-
-
33847630405
-
Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
-
Elias, J. E., and Gygi, S. P. (2007) Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nat. Methods 4, 207-214
-
(2007)
Nat. Methods
, vol.4
, pp. 207-214
-
-
Elias, J.E.1
Gygi, S.P.2
-
20
-
-
0020045888
-
Diabetes-obesity syndromes in mice
-
Coleman, D. L. (1982) Diabetes-obesity syndromes in mice. Diabetes 31, 1-6
-
(1982)
Diabetes
, vol.31
, pp. 1-6
-
-
Coleman, D.L.1
-
21
-
-
0014004384
-
Diabetes, a new mutation in the mouse
-
Hummel, K. P., Dickie, M. M., and Coleman, D. L. (1966) Diabetes, a new mutation in the mouse. Science 153, 1127-1128
-
(1966)
Science
, vol.153
, pp. 1127-1128
-
-
Hummel, K.P.1
Dickie, M.M.2
Coleman, D.L.3
-
22
-
-
84880791239
-
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways
-
Park, J., Chen, Y., Tishkoff, D. X., Peng, C., Tan, M., Dai, L., Xie, Z., Zhang, Y., Zwaans, B. M., Skinner, M. E., Lombard, D. B., and Zhao, Y. (2013) SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol. Cell 50, 919-930
-
(2013)
Mol. Cell
, vol.50
, pp. 919-930
-
-
Park, J.1
Chen, Y.2
Tishkoff, D.X.3
Peng, C.4
Tan, M.5
Dai, L.6
Xie, Z.7
Zhang, Y.8
Zwaans, B.M.9
Skinner, M.E.10
Lombard, D.B.11
Zhao, Y.12
-
23
-
-
84892511644
-
Large-scale gene function analysis with the PANTHER classification system
-
Mi, H., Muruganujan, A., Casagrande, J. T., and Thomas, P. D. (2013) Large-scale gene function analysis with the PANTHER classification system. Nat. Protoc. 8, 1551-1566
-
(2013)
Nat. Protoc.
, vol.8
, pp. 1551-1566
-
-
Mi, H.1
Muruganujan, A.2
Casagrande, J.T.3
Thomas, P.D.4
-
24
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da, W., Sherman, B. T., and Lempicki, R. A. (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57
-
(2009)
Nat. Protoc.
, vol.4
, pp. 44-57
-
-
Huang Da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
25
-
-
84876515907
-
STRING v9.1: Protein-protein interaction networks, with increased coverage and integration
-
Franceschini, A., Szklarczyk, D., Frankild, S., Kuhn, M., Simonovic, M., Roth, A., Lin, J., Minguez, P., Bork, P., von Mering, C., and Jensen, L. J. (2013) STRING v9.1: protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res. 41, D808-D815
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D808-D815
-
-
Franceschini, A.1
Szklarczyk, D.2
Frankild, S.3
Kuhn, M.4
Simonovic, M.5
Roth, A.6
Lin, J.7
Minguez, P.8
Bork, P.9
Von Mering, C.10
Jensen, L.J.11
-
26
-
-
2942552459
-
An automated method for finding molecular complexes in large protein interaction networks
-
Bader, G. D., and Hogue, C. W. (2003) An automated method for finding molecular complexes in large protein interaction networks. BMC Bioinformatics 4, 2
-
(2003)
BMC Bioinformatics
, vol.4
, pp. 2
-
-
Bader, G.D.1
Hogue, C.W.2
-
27
-
-
0032556969
-
Familial hyperinsulinism caused by an activating glucokinase mutation
-
Glaser, B., Kesavan, P., Heyman, M., Davis, E., Cuesta, A., Buchs, A., Stanley, C. A., Thornton, P. S., Permutt, M. A., Matschinsky, F. M., and Herold, K. C. (1998) Familial hyperinsulinism caused by an activating glucokinase mutation. N. Engl. J. Med. 338, 226-230
-
(1998)
N. Engl. J. Med.
, vol.338
, pp. 226-230
-
-
Glaser, B.1
Kesavan, P.2
Heyman, M.3
Davis, E.4
Cuesta, A.5
Buchs, A.6
Stanley, C.A.7
Thornton, P.S.8
Permutt, M.A.9
Matschinsky, F.M.10
Herold, K.C.11
-
28
-
-
0026608764
-
Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus
-
Froguel, P., Vaxillaire, M., Sun, F., Velho, G., Zouali, H., Butel, M. O., Lesage, S., Vionnet, N., Clement, K., Fougerousse, F., Tanizawa, Y., Weissenbach, J., Beckmann, J. S., Lathrop, G. M., Passa, P., Permutt, M. A., and Cohen, D. (1992) Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus. Nature 356, 162-164
-
(1992)
Nature
, vol.356
, pp. 162-164
-
-
Froguel, P.1
Vaxillaire, M.2
Sun, F.3
Velho, G.4
Zouali, H.5
Butel, M.O.6
Lesage, S.7
Vionnet, N.8
Clement, K.9
Fougerousse, F.10
Tanizawa, Y.11
Weissenbach, J.12
Beckmann, J.S.13
Lathrop, G.M.14
Passa, P.15
Permutt, M.A.16
Cohen, D.17
-
29
-
-
0034034229
-
Glucose-6-phosphatase flux in vitro is increased in type 2 diabetes
-
Clore, J. N., Stillman, J., and Sugerman, H. (2000) Glucose-6-phosphatase flux in vitro is increased in type 2 diabetes. Diabetes 49, 969-974
-
(2000)
Diabetes
, vol.49
, pp. 969-974
-
-
Clore, J.N.1
Stillman, J.2
Sugerman, H.3
-
30
-
-
0031031276
-
Induction of hepatic glucose-6-phosphatase gene expression by lipid infusion
-
Massillon, D., Barzilai, N., Hawkins, M., Prus-Wertheimer, D., and Rossetti, L. (1997) Induction of hepatic glucose-6-phosphatase gene expression by lipid infusion. Diabetes 46, 153-157
-
(1997)
Diabetes
, vol.46
, pp. 153-157
-
-
Massillon, D.1
Barzilai, N.2
Hawkins, M.3
Prus-Wertheimer, D.4
Rossetti, L.5
-
31
-
-
0031442028
-
Deficiency of phosphofructo-1-kinase/muscle subtype in humans impairs insulin secretion and causes insulin resistance
-
Ristow, M., Vorgerd, M., Mohlig, M., Schatz, H., and Pfeiffer, A. (1997) Deficiency of phosphofructo-1-kinase/muscle subtype in humans impairs insulin secretion and causes insulin resistance. J. Clin. Invest. 100, 2833-2841
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2833-2841
-
-
Ristow, M.1
Vorgerd, M.2
Mohlig, M.3
Schatz, H.4
Pfeiffer, A.5
-
32
-
-
0032539696
-
Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo
-
Martin, W. H., Hoover, D. J., Armento, S. J., Stock, I. A., McPherson, R. K., Danley, D. E., Stevenson, R. W., Barrett, E. J., and Treadway, J. L. (1998) Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo. Proc. Natl. Acad. Sci. U.S.A. 95, 1776-1781
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 1776-1781
-
-
Martin, W.H.1
Hoover, D.J.2
Armento, S.J.3
Stock, I.A.4
McPherson, R.K.5
Danley, D.E.6
Stevenson, R.W.7
Barrett, E.J.8
Treadway, J.L.9
-
33
-
-
84885124677
-
Metabolic characterization of a sirt5 deficient mouse model
-
Yu, J., Sadhukhan, S., Noriega, L. G., Moullan, N., He, B., Weiss, R. S., Lin, H., Schoonjans, K., and Auwerx, J. (2013) Metabolic characterization of a Sirt5 deficient mouse model. Sci. Rep. 3, 2806
-
(2013)
Sci. Rep.
, vol.3
, pp. 2806
-
-
Yu, J.1
Sadhukhan, S.2
Noriega, L.G.3
Moullan, N.4
He, B.5
Weiss, R.S.6
Lin, H.7
Schoonjans, K.8
Auwerx, J.9
-
34
-
-
77149148756
-
Regulation of cellular metabolism by protein lysine acetylation
-
Zhao, S., Xu, W., Jiang, W., Yu, W., Lin, Y., Zhang, T., Yao, J., Zhou, L., Zeng, Y., Li, H., Li, Y., Shi, J., An, W., Hancock, S. M., He, F., Qin, L., Chin, J., Yang, P., Chen, X., Lei, Q., Xiong, Y., and Guan, K. L. (2010) Regulation of cellular metabolism by protein lysine acetylation. Science 327, 1000-1004
-
(2010)
Science
, vol.327
, pp. 1000-1004
-
-
Zhao, S.1
Xu, W.2
Jiang, W.3
Yu, W.4
Lin, Y.5
Zhang, T.6
Yao, J.7
Zhou, L.8
Zeng, Y.9
Li, H.10
Li, Y.11
Shi, J.12
An, W.13
Hancock, S.M.14
He, F.15
Qin, L.16
Chin, J.17
Yang, P.18
Chen, X.19
Lei, Q.20
Xiong, Y.21
Guan, K.L.22
more..
-
35
-
-
84903141990
-
Diabetes induces lysine acetylation of intermediary metabolism enzymes in the kidney
-
Kosanam, H., Thai, K., Zhang, Y., Advani, A., Connelly, K. A., Diamandis, E. P., and Gilbert, R. E. (2014) Diabetes induces lysine acetylation of intermediary metabolism enzymes in the kidney. Diabetes 63, 2432-2439
-
(2014)
Diabetes
, vol.63
, pp. 2432-2439
-
-
Kosanam, H.1
Thai, K.2
Zhang, Y.3
Advani, A.4
Connelly, K.A.5
Diamandis, E.P.6
Gilbert, R.E.7
-
36
-
-
84897565291
-
Lysine glutarylation is a protein post-translational modification regulated by SIRT5
-
Tan, M., Peng, C., Anderson, K. A., Chhoy, P., Xie, Z., Dai, L., Park, J., Chen, Y., Huang, H., Zhang, Y., Ro, J., Wagner, G. R., Green, M. F., Madsen, A. S., Schmiesing, J., Peterson, B. S., Xu, G., Ilkayeva, O. R., Muehlbauer, M. J., Braulke, T., Muhlhausen, C., Backos, D. S., Olsen, C. A., McGuire, P. J., Pletcher, S. D., Lombard, D. B., Hirschey, M. D., and Zhao, Y. (2014) Lysine glutarylation is a protein post-translational modification regulated by SIRT5. Cell Metab. 19, 605-617
-
(2014)
Cell Metab.
, vol.19
, pp. 605-617
-
-
Tan, M.1
Peng, C.2
Anderson, K.A.3
Chhoy, P.4
Xie, Z.5
Dai, L.6
Park, J.7
Chen, Y.8
Huang, H.9
Zhang, Y.10
Ro, J.11
Wagner, G.R.12
Green, M.F.13
Madsen, A.S.14
Schmiesing, J.15
Peterson, B.S.16
Xu, G.17
Ilkayeva, O.R.18
Muehlbauer, M.J.19
Braulke, T.20
Muhlhausen, C.21
Backos, D.S.22
Olsen, C.A.23
McGuire, P.J.24
Pletcher, S.D.25
Lombard, D.B.26
Hirschey, M.D.27
Zhao, Y.28
more..
|