Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency

Journal of Allergy and Clinical Immunology

Volumn 135, Issue 1, 2015, Pages 283-287.e5

  Van Eyck, Lien ^a   Hershfield, Michael S ^b   Pombal, Diana ^a   Kelly, Susan J ^b   Ganson, Nancy J ^b   Moens, Leen ^a   Frans, Glynis ^a   Schaballie, Heidi ^c   De Hertogh, Gert ^a   Dooley, James ^a   Bossuyt, Xavier ^a   Wouters, Carine ^c   Liston, Adrian ^a   Meyts, Isabelle ^c  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ADENOSINE DEAMINASE; ADENOSINE DEAMINASE 2; AMOXICILLIN PLUS CLAVULANIC ACID; BUSULFAN; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; FLUCONAZOLE; IMMUNOGLOBULIN; INTERLEUKIN 6; MERCAPTOPURINE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; POLYSACCHARIDE VACCINE; PREDNISONE; RAPAMYCIN; RITUXIMAB; TACROLIMUS; UNCLASSIFIED DRUG; CECR1 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; SIGNAL PEPTIDE;

ABDOMINAL PAIN; ADD ON THERAPY; ADENOSINE DEAMINASE 2 DEFICIENCY; ADENOSINE DEAMINASE DEFICIENCY; ADENOVIRIDAE; ANTIBIOTIC THERAPY; AUTOIMMUNITY; BACTERIUM CULTURE; BALANCE DISORDER; BRAIN HEMORRHAGE; CASE REPORT; CD4+ T LYMPHOCYTE; CHILD; COMBINED IMMUNODEFICIENCY; COMMON VARIABLE IMMUNODEFICIENCY; COMPUTER ASSISTED TOMOGRAPHY; CONSERVATIVE TREATMENT; COOMBS POSITIVE HEMOLYTIC ANEMIA; CORTICOSTEROID THERAPY; DISEASE COURSE; DRIED BLOOD SPOT TESTING; DRUG DOSE REDUCTION; ENGRAFTMENT SYNDROME; ENZYME ACTIVITY; ERYTHROBLASTOPENIA; FEVER; FOLLOW UP; GENE LOCATION; GENE SEQUENCE; GENERALIZED LYMPHADENOPATHY; GRAFT VERSUS HOST REACTION; GROWTH DISORDER; HEADACHE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEPATOSPLENOMEGALY; HERPES SIMPLEX; HUMAN; HUMAN TISSUE; ILEUS; IMMUNOGLOBULIN DEFICIENCY; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE BIOPSY; INTESTINE OBSTRUCTION; INTESTINE RESECTION; LETTER; LONG TERM CARE; LYMPHADENITIS; LYMPHADENOPATHY; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOPENIA; MALE; MISSENSE MUTATION; MYCOSIS; NEUROIMAGING; NEUTROPENIA; NOROVIRUS; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCYTOPENIA; PHENOTYPE; POLYOMA VIRUS; PRESCHOOL CHILD; RECEPTOR BINDING; REGULATORY T LYMPHOCYTE; RELAPSE; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SCHOOL CHILD; SIBLING; SPLENOMEGALY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; THROMBOCYTOPENIA; TRANSIENT ISCHEMIC ATTACK; TREATMENT RESPONSE; ULCERATIVE COLITIS; VASCULAR DISEASE; VEIN OCCLUSION; VIRUS DETECTION; VIRUS INFECTION; VIRUS REACTIVATION; WATER DEPRIVATION; AGAMMAGLOBULINEMIA; BLOOD; DEFICIENCY; GENETICS; IMMUNOLOGY; INFANT; LYMPHOCYTE COUNT; MUTATION; SEVERE COMBINED IMMUNODEFICIENCY;

ADENOSINE DEAMINASE; AGAMMAGLOBULINEMIA; CHILD, PRESCHOOL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFANT; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-6; LYMPHOCYTE COUNT; MALE; MUTATION; PHENOTYPE; SEVERE COMBINED IMMUNODEFICIENCY;

EID: 84920399194     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.10.010     Document Type: Article

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