How IGF-1 activates its receptor

eLife

Volumn 3, Issue , 2014, Pages

  Kavran, Jennifer M ^a   McCabe, Jacqueline M ^a   Byrne, Patrick O ^a   Connacher, Mary Katherine ^a   Wang, Zhihong ^a   Ramek, Alexander ^a   Sarabipour, Sarvenaz ^a   Shan, Yibing ^a   Shaw, David E ^a   Hristova, Kalina ^a   Cole, Philip A ^a   Leahy, Daniel J ^a  

^a Johns Hopkins University   (United States)

Author keywords

biochemistry; biophysics; FRET; human; IGF1 receptor; kinetics; mechanism; structural biology

Indexed keywords

INSULIN RECEPTOR; LIGAND; PROTEIN BINDING; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CONSERVED SEQUENCE; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; MOUSE; MUTATION; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; HEK293 CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LIGANDS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN;

EID: 84920373653     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.03772     Document Type: Article

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