(±)-torreyunlignans A-D, Rare 8-9′ linked neolignan enantiomers as phosphodiesterase-9A inhibitors from torreya yunnanensis

Journal of Natural Products

Volumn 77, Issue 12, 2014, Pages 2651-2657

  Cheng, Zhong Bin ^a   Lu, Xiao ^a   Bao, Jing Mei ^a   Han, Qing Hua ^a   Dong, Zhen ^a   Tang, Gui Hua ^a   Gan, Li She ^b   Luo, Hai Bin ^a   Yin, Sheng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; ENZYME INHIBITOR; NEOLIGNAN; PHOSPHODIESTERASE 9A INHIBITOR; TORREYUNLIGNANS A; TORREYUNLIGNANS B; TORREYUNLIGNANS C; TORREYUNLIGNANS D; TRITIUM; UNCLASSIFIED DRUG; CYCLIC AMP PHOSPHODIESTERASE; HERBACEOUS AGENT; LIGNAN; PDE9A PROTEIN, HUMAN; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR;

ARTICLE; BINDING AFFINITY; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; ENANTIOMER; IC50; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; TAXACEAE; TORREYA YUNNANENSIS; TRUNK; CHEMICAL STRUCTURE; CHEMISTRY; DIAGNOSTIC USE; DRUG EFFECTS; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE; PLANT STEM; STEREOISOMERISM;

TORREYA FARGESII VAR. YUNNANENSIS;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; CYCLIC AMP; DRUGS, CHINESE HERBAL; LIGNANS; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PLANT STEMS; STEREOISOMERISM; TAXACEAE;

EID: 84920171165     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np500528u     Document Type: Article

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