Functional genetic approach identifies MET, HER3, IGF1R, INSR pathways as determinants of lapatinib unresponsiveness in HER2-positive gastric cancer

Clinical cancer research : an official journal of the American Association for Cancer Research

Volumn 20, Issue 17, 2014, Pages 4559-4573

  Zhang, Zhe ^a   Wang, Jiping ^a   Ji, Dongmei ^a   Wang, Chenchen ^a   Liu, Rujiao ^a   Wu, Zheng ^a   Liu, Lian ^a   Zhu, Dan ^a   Chang, Jinjia ^a   Geng, Ruixuan ^a   Xiong, Lei ^a   Fang, Qiangyi ^a   Li, Jin ^a  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; ERBB2 PROTEIN, HUMAN; ERBB3 PROTEIN, HUMAN; INSR PROTEIN, HUMAN; INSULIN RECEPTOR; LAPATINIB; LEUKOCYTE ANTIGEN; QUINAZOLINE DERIVATIVE; SCATTER FACTOR RECEPTOR; SOMATOMEDIN C RECEPTOR;

APOPTOSIS; DRUG RESISTANCE; FEMALE; GENETICS; HUMAN; MIDDLE AGED; PATHOLOGY; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TUMOR CELL LINE;

ANTIGENS, CD; APOPTOSIS; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-MET; QUINAZOLINES; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

EID: 84920162961     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-3396     Document Type: Article

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