Modelling the impact of fractionation on late urinary toxicity after postprostatectomy radiation therapy

International Journal of Radiation Oncology Biology Physics

Volumn 90, Issue 5, 2014, Pages 1250-1257

  Fiorino, Claudio ^a   Cozzarini, Cesare ^a   Rancati, Tiziana ^b   Briganti, Alberto ^a   Cattaneo, Giovanni Mauro ^a   Mangili, Paola ^a   Di Muzio, Nadia Gisella ^a   Calandrino, Riccardo ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PATIENT MONITORING; SENSITIVITY ANALYSIS; SURGERY; TOXICITY;

AREA UNDER THE CURVES; CONVENTIONAL FRACTIONATIONS; GOODNESS OF FIT; HYPOFRACTIONATION; LIKELIHOOD RATIO TESTS; LINEAR-QUADRATIC MODELS; METHODS AND MATERIALS; REASONABLE VALUE;

RADIOTHERAPY;

ANTIHYPERTENSIVE AGENT;

AGED; ARTICLE; CANCER RADIOTHERAPY; HEMATURIA; HUMAN; MAJOR CLINICAL STUDY; MALE; MODEL; MORBIDITY; POSTOPERATIVE CARE; PROSTATE CANCER; PROSTATECTOMY; RADIATION DOSE FRACTIONATION; SENSITIVITY ANALYSIS; TOXICITY; URETHRA STENOSIS; URINE INCONTINENCE; AREA UNDER THE CURVE; COMPLICATION; INCIDENCE; MIDDLE AGED; POSTOPERATIVE PERIOD; PROSTATIC NEOPLASMS; RADIATION INJURIES; RADIATION RESPONSE; RELATIVE BIOLOGIC EFFECTIVENESS; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL; TIME; URETHRAL STRICTURE; URINARY INCONTINENCE;

AGED; AREA UNDER CURVE; DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; HEMATURIA; HUMANS; INCIDENCE; LINEAR MODELS; MALE; MIDDLE AGED; POSTOPERATIVE PERIOD; PROSTATECTOMY; PROSTATIC NEOPLASMS; RADIATION INJURIES; RELATIVE BIOLOGICAL EFFECTIVENESS; SENSITIVITY AND SPECIFICITY; TIME FACTORS; URETHRAL STRICTURE; URINARY INCONTINENCE;

EID: 84920123173     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2014.08.347     Document Type: Article

References (35)

1. W. Dorr Pathogenesis of normal tissue side-effects M. Joiner, A. Van der Kogel, Basic Clinical Radiobiology Fourth edition 2009 Edward Arnold London 169 190
2. A.N. Viswanathan, E.D. Yorke, and L.B. Marks Radiation dose volume effects of the urinary bladder Int J Radiat Oncol Biol Phys 76 Suppl. 3 2010 S123 S129
3. C. Fiorino, R. Valdagni, and T. Rancati Dose-volume effects for normal tissues in external radiotherapy: Pelvis Radiother Oncol 93 2009 153 167
4. L.B. Marks, P.R. Carroll, and T.C. Dugan The response of the urinary bladder, urethra and ureter to radiation and chemotherapy Int J Radiat Oncol Biol Phys 31 1995 1257 1280
5. L. Budaus, M. Bolla, and A. Bossi Functional outcome and complications following radiation therapy for prostate cancer: A critical analysis of the literature Eur Urol 61 2012 112 127
6. C. Cozzarini, C. Fiorino, and L.F. Da Pozzo Clinical factors predicting late severe urinary toxicity after postoperative radiotherapy for prostate carcinoma: A single-institute analysis of 742 patients Int J Radiat Oncol Biol Phys 82 2012 191 199
7. C. Cozzarini, C. Fiorino, and G.L. Ceresoli Significant correlation between rectal DVH and late bleeding in patients treated after radical prostatectomy with conformal or conventional radiotherapy (66.6-70.2 Gy) Int J Radiat Oncol Biol Phys 55 2003 688 694
8. C. Cozzarini, C. Fiorino, and N. Di Muzio Hypofractionated adjuvant radiotherapy with helical Tomotherapy after radical prostatectomy: Planning data and toxicity results of a Phase I-II study Radiother Oncol 88 2008 26 33
9. C. Cozzarini, C. Fiorino, and N. Di Muzio Significant reduction of acute toxicity following pelvic irradiation with helical tomotherapy in patients with localized prostate cancer Radiother Oncol 84 2007 164 170
10. F. Alongi, C. Fiorino, and C. Cozzarini IMRT significantly reduces acute toxicity of whole-pelvis irradiation in patients treated with post-operative adjuvant or salvage radiotherapy after radical prostatectomy Radiother Oncol 93 2009 207 212
11. T.J. Kruser, D.F. Jarrard, and A.K. Graf Early hypofractionated salvage radiotherapy for postprostatectomy biochemical recurrence Cancer 117 2011 2629 2636
12. S. Krause, F. Sterzing, and D. Neuhof Hypofractionated helical intensity-modulated radiotherapy of the prostate bed after prostatectomy with or without the pelvic lymph nodes - the PRIAMOS trial BMC Cancer 12 2012 504 510
13. L.W. Lee, C.A. McBain, and R. Swindell Hypofractionated radiotherapy as salvage for rising prostate-specific antigen after radical prostatectomy Clin Oncol (R Coll Radiol) 16 2004 517 522
14. Cozzarini C, Fiorino C, Deantoni C et al. Higher than expected severe (grade 3-4) late urinary toxicity after post-prostatectomy hypofractionated radiotherapy: A single institution analysis of 1176 patients. Eur Urol (In press).
15. J.A. Fowler The radiobiology of prostate cancer including new aspects of fractionated radiotherapy Acta Oncol 44 2005 265 276
16. J. Jaal, and W. Dorr Radiation-induced damage to mouse urothelial barrier Radiother Oncol 80 2006 250 256
17. W. Dorr, and S.M. Bentzen Late functional response of mouse urinary bladder to fractionated X-irradiation Int J Radiat Biol 75 1999 1307 1315
18. J.H. Dorr, and J.H. Hendry Consequential late effects in normal tissues Radiother Oncol 61 2001 223 231
19. T. Rancati, C. Fiorino, and G. Gagliardi Fitting late rectal bleeding data using different NTCP models: Results from an Italian multi-centric study (AIROPROS0101) Radiother Oncol 73 2004 21 32
20. H.D. Thames, S.M. Bentzen, and I. Turesson Time-dose factors in radiotherapy: A review of the human data Radiother Oncol 19 1990 219 235
21. W.D. Heemsbergen, A. Al-Mamgani, and M.G. Witte Urinary obstruction in prostate cancer patients from the Dutch trial (68Gy vs 78Gy): Relationship with local dose, acute effects and baseline characteristics Int J Radiat Oncol Biol Phys 78 2010 19 25
22. C. Fleming, C. Kelly, and P. Thirion A method for the prediction of late organ-at-risk toxicity after radiotherapy of the prostate using equivalent uniform dose Int J Radiat Oncol Biol Phys 80 2011 608 613
23. P. Ghadjar, M.J. Zelefsky, and D.E. Spratt Impact of dose to the bladder trigone on long-term urinary function after high-dose intensity modulated radiation therapy for localized prostate cancer Int J Radiat Oncol Biol Phys 88 2014 339 344
24. P.E. Gill, W.M. Murray, and M.A. Saunders User Guide for NPSOL (Version 4.0): A FORTRAN Package for Nonlinear Programming Technical Report SOL 1986 Stanford University, Department of Operations Research Stanford, CA 86 92
25. F.A. Stewart Mechanism of bladder damage and repair after treatment with radiation and cytostatic drugs Br J Cancer Suppl. 7 1986 280 291
26. S.M. Bentzen, F. Lundbeck, and L.L. Christensen Fractionation sensitivity and late radiation injury to the mouse urinary bladder Radiother Oncol 25 1992 301 307
27. W. Dorr, M. Eckhardt, and A. Ehme Pathogenesis of acute radiation effects in the urinary bladder. Experimental results Strahlenther Onkol 174 Suppl. 3 1998 93 95
28. J. Jaal, and W. Dorr Radiation induced late damage to the barrier function of small blood vessels in mouse bladder J Urol 176 2006 2696 2700
29. A. Cabrera, and W.R. Lee Hypofractionation for localized prostate cancer Semin Radiat Oncol 23 2013 191 197
30. A. Pollack, G. Walker, and E.M. Horwitz Randomized trial of hypofractionated external-beam radiotherapy for prostate cancer J Clin Oncol 31 2013 3860 3868
31. S. Arcangeli, L. Strigari, and S. Gomellini Updated results and patterns of failure in a randomized hypofractionation trial for high-risk prostate cancer Int J Radiat Oncol Biol Phys 84 2012 1172 1180
32. K.E. Hoffmann, K.R. Voong, and T.J. Pugh Risk of late toxicity in men receiving dose-escalated hypofractionated intensity modulated prostate radiation therapy: Results from a randomized trial Int J Radiat Oncol Biol Phys 88 2014 1074 1084
33. P.A. Kupelian, T.R. Willoughby, and C.A. Reddy Hypofractionated intensity-modulated radiotherapy (70Gy at 2.5 Gy per fraction) for localized prostate cancer: Cleveland clinical experience Int J Radiat Oncol Biol Phys 68 2007 1424 1430
34. L. Sullivan, S.G. Williams, and K.H. Tai Urethral stricture following high dose rate brachytherapy for prostate cancer Radiother Oncol 91 2009 232 236
35. V. Carillo, C. Cozzarini, and T. Rancati Relationships between bladder dose-volume/surface histograms parameters and acute urinary toxicity after radiotherapy for prostate cancer Radiother Oncol 111 2014 100 105.