Long-term outcomes of hypofractionation versus conventional radiation therapy after breast-conserving surgery for ductal carcinoma in situ of the breast

International Journal of Radiation Oncology Biology Physics

Volumn 90, Issue 5, 2014, Pages 1017-1024

  Lalani, Nafisha ^a,b,c   Paszat, Lawrence ^a,b,c   Sutradhar, Rinku ^c   Thiruchelvam, Deva ^c   Nofech Mozes, Sharon ^a,b   Hanna, Wedad ^a,b   Slodkowska, Elzbieta ^a,b   Done, Susan J ^a,d   Miller, Naomi ^a,d   Youngson, Bruce ^a,d   Tuck, Alan ^e   Sengupta, Sandip ^f   Elavathil, Leela ^g   Chang, Martin C ^h   Jani, Prashant A ⁱ   Bonin, Michel ^j   Rakovitch, Eileen ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^c INSTITUTE FOR CLINICAL EVALUATIVE SCIENCES   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

^e ST JOSEPH S HEALTH CENTRE   (Canada)

^f KINGSTON GENERAL HOSPITAL   (Canada)

^g HAMILTON HEALTH SCIENCES   (Canada)

^h MOUNT SINAI HOSPITAL   (Canada)

ⁱ THUNDER BAY REGIONAL HEALTH SCIENCES CENTRE   (Canada)

^j SUDBURY REGIONAL HOSPITAL   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSIS; MULTIVARIANT ANALYSIS; RADIOTHERAPY; RISK ASSESSMENT; SURGERY;

BREAST CONSERVING SURGERY; BREAST RADIATION THERAPY; CONVENTIONAL RADIATION THERAPY; DUCTAL CARCINOMA IN SITU; INTER QUARTILE RANGES; METHODS AND MATERIALS; MULTI VARIATE ANALYSIS; MULTIVARIABLE ANALYSIS;

RADIATION;

ADULT; ARTICLE; CANADA; CANCER RECURRENCE; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; INTERMETHOD COMPARISON; INTRADUCTAL CARCINOMA; LOCAL RECURRENCE FREE SURVIVAL; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; OUTCOME ASSESSMENT; PARTIAL MASTECTOMY; POSTOPERATIVE CARE; PROPENSITY SCORE; RADIATION DOSE FRACTIONATION; RECURRENCE RISK; SURVIVAL RATE; SURVIVAL TIME; ADJUVANT THERAPY; AGED; ANALYSIS OF VARIANCE; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; DISEASE FREE SURVIVAL; MIDDLE AGED; MORTALITY; PATHOLOGY; PROCEDURES; RADIATION DOSE; RETREATMENT; RISK; SEGMENTAL MASTECTOMY; STATISTICS AND NUMERICAL DATA; TUMOR RECURRENCE; UTILIZATION;

AGED; ANALYSIS OF VARIANCE; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; DISEASE-FREE SURVIVAL; DOSE FRACTIONATION; FEMALE; HUMANS; MASTECTOMY, SEGMENTAL; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; ONTARIO; PROPENSITY SCORE; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; RETREATMENT; RISK;

EID: 84919959799     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2014.07.026     Document Type: Article

References (13)

1. B.A. Virnig, T.M. Tuttle, and T. Shamliyan Ductal carcinoma in situ of the breast: A systematic review of incidence, treatment, and outcomes J Natl Cancer Inst 102 2010 170 178
2. C. Correa, P. McGale, and C. Taylor Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast J Natl Cancer Inst Monogr 41 2010 162 177
3. E. Rakovitch, S.A. Narod, and S. Nofech-Moses Impact of boost radiation in the treatment of ductal carcinoma in situ: A population based analysis Int J Radiat Oncol Biol Phys 86 2013 491 497
4. E. Rakovitch, J.P. Pignol, and C. Chartier The management of ductal carcinoma in situ of the breast: A screened population-based analysis Breast Cancer Res Treat 101 2007 335 347
5. E.S. Wai, M.L. Lesperance, and C.S. Alexander Effect of radiotherapy boost and hypofractionation on outcomes in ductal carcinoma in situ Cancer 117 2011 54 62
6. D. Williamson, R. Dinniwell, and S. Fung Local control with conventional and hypofractionated adjuvant radiotherapy after breast-conserving surgery for ductal carcinoma in-situ Radiother Oncol 95 2010 317 320
7. T. Whelan, R. MacKenzie, and J. Julian Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer J Natl Cancer Inst 94 2002 1143 1150
8. S.M. Bentzen, R.K. Agrawal, and E.G. Aird The UK standardisation of breast radiotherapy (START) trial A of radiotherapy hypofractionation for treatment of early breast cancer: A randomised trial Lancet Oncol 9 2008 331 334
9. S.M. Bentzen, R.K. Agrawal, and E.G. Aird The UK standardisation of breast radiotherapy (START) trial B of radiotherapy hypofractionation for treatment of early breast cancer: A randomised trial Lancet 371 2008 1098 1107
10. R. Ciervide, S. Dhage, and A. Guth Five year outcome of 145 patients with ductal carcinoma in situ (DCIS) after accelerated breast radiotherapy Int J Radiat Oncol Biol Phys 83 2012 159 164
11. L. Hathout, T. Hijal, and V. Thebérge Hypofractionated radiation therapy for breast ductal carcinoma in situ Int J Radiat Oncol Biol Phys 87 2013 1058 1063
12. P.C. Austin An introduction to propensity score methods for reducing the effects of confounding in observational studies Multivariate Behav Res 46 2011 399 424
13. http://public.ukcrn.org.uk/search/StudyDetail.aspx?StudyID=8971. Accessed July 2, 2014.