Anti-B cell therapy with rituximab as induction therapy in renal transplantation

Transplant Immunology

Volumn 31, Issue 4, 2014, Pages 207-209

  Joosten, I ^a   Baas, M C ^a   Kamburova, E G ^a   van den Hoogen, M W F ^a   Koenen, H J P M ^a   Hilbrands, L B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

B cells; Immunosuppression; Kidney transplantation; Rituximab

Indexed keywords

CD27 ANTIGEN; FC RECEPTOR; IMMUNOGLOBULIN D; INTERLEUKIN 10; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PANEL REACTIVE ANTIBODY; PLACEBO; RITUXIMAB; STEROID; TACROLIMUS;

ACUTE GRAFT REJECTION; ANTIBODY MEDIATED REJECTION; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CYTOKINE RELEASE; HIGH RISK PATIENT; HUMAN; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; KIDNEY BIOPSY; KIDNEY TRANSPLANTATION; LYMPH NODE; LYMPHOCYTE DIFFERENTIATION; MALIGNANT NEOPLASTIC DISEASE; MEMORY CELL; MEMORY T LYMPHOCYTE; NATURAL KILLER CELL; NEUTROPENIA; PRE B LYMPHOCYTE; REGULATORY T LYMPHOCYTE; SINGLE DRUG DOSE; T LYMPHOCYTE ACTIVATION; TH17 CELL;

EID: 84919876812     PISSN: 09663274     EISSN: 18785492     Source Type: Journal    
DOI: 10.1016/j.trim.2014.09.011     Document Type: Article

References (6)

1. van den Hoogen M.W.F., Hilbrands L.B. Use of monoclonal antibodies in renal transplantation. Immunotherapy 2011, 3:871-880.
2. van den Hoogen M.W.F., Kamburova E.G., Baas M.C., Steenbergen E.J., Florquin S., Koenen H.J.P.M., et al. Rituximab as induction therapy after renal transplantation; a randomised, double-blind, placebo-controlled study of efficacy and safety. Am J Transplant 2014, [Accepted for publication].
3. Kamburova E.G., Koenen H.J.P.M., van den Hoogen M.W.F., Baas M.C., Joosten I., Hilbrands L.B. Longitudinal analysis of T and B cell phenotype and function in renal transplant recipients with or without rituximab induction therapy, Plos One 2014, [Accepted for publication].
4. Kamburova E.G., Koenen H.J.P.M., Boon L., Hilbrands L.B., Joosten I. In vitro effects of rituximab on the proliferation, activation and differentiation of human B cells. Am J Transplant 2012, 12:341-350.
5. Kamburova E.G., Koenen H.J.P.M., Borgman K.J., ten Berge I.J., Joosten I., Hilbrands L.B. A single dose of rituximab does not deplete B cells in secondary lymphoid organs but alters phenotype and function. Am J Transplant 2013, 13:1503-1511.
6. Kamburova E.G., van den Hoogen M.W.F., Koenen H.J.P.M., Baas M.C., Hilbrands L.B., Joosten I. Cytokine release after treatment with rituximab in renal transplant recipients, Transplantation 2014, [Accepted for publication].