Genetic variants at 1q32.1, 10q11.2 and 19q13.41 are associated with prostate-specific antigen for prostate cancer screening in two Korean population-based cohort studies

Gene

Volumn 556, Issue 2, 2015, Pages 199-205

  Kim, Soriul ^a   Shin, Chol ^b   Jee, Sun Ha ^a  

^a Yonsei University   (South Korea)

^b Korea University   (South Korea)

Author keywords

Genetic risk score (GRS); Genome wide association study; Prostate cancer; Prostate specific antigen (PSA)

Indexed keywords

PROSTATE SPECIFIC ANTIGEN; CARRIER PROTEIN; SLC45A3 PROTEIN, HUMAN;

ADULT; ARTICLE; CANCER RISK; CANCER SCREENING; CHROMOSOME 10Q; CHROMOSOME 19Q; CHROMOSOME 1Q; CONTROLLED STUDY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; KOREAN (PEOPLE); MAJOR CLINICAL STUDY; MALE; PROSTATE CANCER; SINGLE NUCLEOTIDE POLYMORPHISM; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD; CHROMOSOME 1; CHROMOSOME 10; CHROMOSOME 19; COHORT ANALYSIS; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; PROSTATIC NEOPLASMS; SOUTH KOREA; STATISTICAL MODEL;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 19; COHORT STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LINEAR MODELS; MALE; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; REPUBLIC OF KOREA;

EID: 84919875949     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2014.11.059     Document Type: Article

References (41)

1. Baik I., et al. Association of snoring with chronic bronchitis. Arch. Intern. Med. 2008, 168(2):167-173.
2. Bansal A., Murray D.K., Wu J.T., Stephenson R.A., Middleton R.G., Meikle A.W. Heritability of prostate-specific antigen and relationship with zonal prostate volumes in aging twins. J. Clin. Endocrinol. Metab. 2000, 85(3):1272-1276.
3. Cho Y.S., et al. A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits. Nat. Genet. 2009, 41(5):527-534.
4. Cornelis M.C., et al. Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry. Ann. Intern. Med. 2009, 150(8):541-550.
5. Eeles R.A., et al. Multiple newly identified loci associated with prostate cancer susceptibility. Nat. Genet. 2008, 40(3):316-321.
6. Gauderman W.J. Sample size requirements for association studies of gene-gene interaction. Am. J. Epidemiol. 2002, 155:478-484.
7. Gudmundsson J., et al. Genetic correction of PSA values using sequence variants associated with PSA levels. Sci. Transl. Med. 2010, 2(62):62ra92.
8. Hernández J., Thompson I.M. Prostate-specific antigen: a review of the validation of the most commonly used cancer biomarker. Cancer 2004, 101(5):894-904.
9. Jee S.H., et al. Adiponectin concentrations: a genome-wide association study. Am. J. Hum. Genet. 2010, 87(4):545-552.
10. Jemal A., Bray F., Center M.M., Ferlay J., Ward E., Forman D. Global cancer statistics. CA Cancer J. Clin. 2011, 61(2):69-90.
11. Jia W.H., et al. Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. Nat. Genet. 2013, 45(2):191-196.
12. Jin G., et al. Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA. Neoplasia 2013, 15(1):95-101.
13. Johnson A.D., Handsaker R.E., Pulit S.L., Nizzari M.M., O'Donnell C.J., de Bakker P.I. SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics 2008, 24(24):2938-2939.
14. Jung K.W., Won Y.J., Kong H.J., Oh C.M., Seo H.G., Lee J.S. Cancer statistics in Korea: incidence, mortality, survival and prevalence in 2010. Cancer Res. Treat. 2013, 45(1):1-14.
15. Kalos M., et al. Prostein expression is highly restricted to normal and malignant prostate tissues. Prostate 2004, 60(3):246-256.
16. Lawrence M.G., Lai J., Clements J.A. Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus. Endocr. Rev. 2010, 31(4):407-446.
17. Mavridis K., Avgeris M., Koutalellis G., Stravodimos K., Scorilas A. Expression analysis and study of the KLK15 mRNA splice variants in prostate cancer and benign prostatic hyperplasia. Cancer Sci. 2010, 101(3):693-699.
18. Nam R.K., et al. A novel serum marker, total prostate secretory protein of 94 amino acids, improves prostate cancer detection and helps identify high grade cancers at diagnosis. J. Urol. 2006, 175(4):1291-1297.
19. Owens C.L., Epstein J.I., Netto G.J. Distinguishing prostatic from colorectal adenocarcinoma on biopsy samples: the role of morphology and immunohistochemistry. Arch. Pathol. Lab. Med. 2007, 131(4):599-603.
20. Pal P., et al. Tagging SNPs in the kallikrein genes 3 and 2 on 19q13 and their associations with prostate cancer in men of European origin. Hum. Genet. 2007, 122(3-4):251-259.
21. Parikh H., et al. A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33. Hum. Genet. 2010, 127(1):91-99.
22. Perner S., et al. Loss of SLC45A3 protein (prostein) expression in prostate cancer is associated with SLC45A3-ERG gene rearrangement and an unfavorable clinical course. Int. J. Cancer 2013, 132(4):807-812.
23. Rabbee N., Speed T.P. A genotype calling algorithm for Affymetrix SNP arrays. Bioinformatics 2006, 22(1):7-12.
24. Reeves J.R., Dulude H., Panchal C., Daigneault L., Ramnani D.M. Prognostic value of prostate secretory protein of 94 amino acids and its binding protein after radical prostatectomy. Clin. Cancer Res. 2006, 12:6018-6022.
25. Romanuik T.L., Wang G., Holt R.A., Jones S.J., Marra M.A., Sadar M.D. Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries. BMC Genomics 2009, 10:476.
26. Satake W., et al. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat. Genet. 2009, 41(12):1303-1307.
27. Schröder F.H., et al. Screening and prostate-cancer mortality in a randomized European study. N. Engl. J. Med. 2009, 360(13):1320-1328.
28. Shin C., et al. Association of habitual snoring with glucose and insulin metabolism in nonobese Korean adult men. Am. J. Respir. Crit. Care Med. 2005, 171(3):287-291.
29. Sull J.W., et al. Serum adiponectin is associated with family history of diabetes independently of obesity and insulin resistance in healthy Korean men and women. Eur. J. Endocrinol. 2009, 160(1):39-43.
30. Sun J., et al. Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population. Hum. Genet. 2013, 132(4):423-429.
31. Taichman R.S., Loberg R.D., Mehra R., Pienta K.J. The evolving biology and treatment of prostate cancer. J. Clin. Invest. 2007, 117(9):2351-2361.
32. Thomas G., et al. Multiple loci identified in a genome-wide association study of prostate cancer. Nat. Genet. 2008, 40(3):310-315.
33. Thompson I.M., et al. Operating characteristics of prostate-specific antigen in men with an initial PSA level of 3.0ng/ml or lower. JAMA 2005, 294(1):66-70.
34. Thompson I.M., et al. Assessing prostate cancer risk: results from the Prostate Cancer Prevention Trial. J. Natl. Cancer Inst. 2006, 98(8):529-534.
35. Tucci A., et al. Genetic variability at the PARK16 locus. Eur. J. Hum. Genet. 2010, 18(12):1356-1359.
36. Weedon M.N., et al. Genome-wide association analysis identifies 20 loci that influence adult height. Nat. Genet. 2008, 40(5):575-583.
37. Wiklund F., et al. Association of reported prostate cancer risk alleles with PSA levels among men without a diagnosis of prostate cancer. Prostate 2009, 69(4):419-427.
38. Xu J., et al. Identification and characterization of prostein, a novel prostate-specific protein. Cancer Res. 2001, 61(4):1563-1568.
39. Xu J., et al. Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Nat. Genet. 2012, 44(11):1231-1235.
40. Yin M., Dhir R., Parwani A.V. Diagnostic utility of p501s (prostein) in comparison to prostate specific antigen (PSA) for the detection of metastatic prostatic adenocarcinoma. Diagn. Pathol. 2007, 2:41.
41. Yousef G.M., Scorilas A., Jung K., Ashworth L.K., Diamandis E.P. Molecular cloning of the human kallikrein 15 gene (KLK15). Up-regulation in prostate cancer. J. Biol. Chem. 2001, 276(1):53-61.