A case of anastrazole-related drug-induced autoimmune hepatitis

Clinical Journal of Gastroenterology

Volumn 7, Issue 5, 2014, Pages 414-417

  Islam, Mohammad Saiful ^a,b   Wright, Gavin ^a,b,c   Tanner, Peter ^d   Lucas, Robert ^d  

^a BASILDON HOSPITAL   (United Kingdom)

^b ST GEORGE S HOSPITAL   (United Kingdom)

^c ROYAL FREE HOSPITAL   (United Kingdom)

^d HAVERING AND REDBRIDGE UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

Anastrazole; Anti oestrogen; Autoimmune; Drug induced liver injury; Liver failure; Liver function tests

Indexed keywords

ACETYLCYSTEINE; ALANINE AMINOTRANSFERASE; ALBUMIN; ANASTROZOLE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; ESTROGEN RECEPTOR; IMMUNOGLOBULIN G; PREDNISOLONE; SMOOTH MUSCLE ANTIBODY; URSODEOXYCHOLIC ACID; VITAMIN K GROUP; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; NITRILE; TRIAZOLE DERIVATIVE;

AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOIMMUNE HEPATITIS; AXILLARY DISSECTION; BILIRUBIN BLOOD LEVEL; BRAIN DISEASE; BREAST CANCER; CASE REPORT; CAUCASIAN; CHRONIC LIVER DISEASE; DISSECTION; DRUG DOSE REDUCTION; EOSINOPHIL; FEMALE; HISTOPATHOLOGY; HOSPITAL ADMISSION; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATORY INFILTRATE; INTERNATIONAL NORMALIZED RATIO; LIVER BIOPSY; LIVER FUNCTION TEST; LIVER INJURY; LIVER PARENCHYMA; LOADING DRUG DOSE; MEDICAL HISTORY; NEUTROPHIL; ONCOLOGIST; PATHOLOGIST; RISK FACTOR; TOXIC HEPATITIS; WIDE EXCISION; DRUG-INDUCED LIVER INJURY; HEPATITIS, AUTOIMMUNE;

AGED; ANTINEOPLASTIC AGENTS, HORMONAL; DRUG-INDUCED LIVER INJURY; FEMALE; HEPATITIS, AUTOIMMUNE; HUMANS; NITRILES; TRIAZOLES;

EID: 84919873401     PISSN: 18657257     EISSN: 18657265     Source Type: Journal    
DOI: 10.1007/s12328-014-0512-4     Document Type: Article

References (15)

1. Simpson ER. Sources of estrogen and their importance. J Steroid Biochem Mol Biol. 2003;86(3–5):225–30.
2. The Arimidex, Tamoxifen, Alone or in Combination (ATAC) Trialists’ Group. Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: long-term safety analysis of the ATAC trial. Lancet Oncol. 2006;7:633–43.
3. Janni W, Hepp P. Adjuvant aromatase inhibitor therapy: outcomes and safety. Cancer Treat Rev. 2010;36(3):249–61.
4. Reynolds TB, Peters RL, Yamada S. Chronic active and lupoid hepatitis caused by a laxative, oxyphenisatin. N Engl J Med. 1971;285(15):813–20. doi:10.1056/NEJM197110072851501.
5. Alessandro Inno et al. Anastrozole-related acute hepatitis with autoimmune features: a case report. BMC Gastroenterol. 2011; 11:32.
6. Björnsson E, Talwalkar J, Treeprasertsuk S, Kamath PS, Takahashi N, Sanderson S, Neuhauser M, Lindor K. Drug-induced autoimmune hepatitis: clinical characteristics and prognosis. Hepatology. 2010;51(6):2040–8. doi:10.1002/hep.23588.
7. Danan G, Benichou C. Causality assessment of adverse reactions to drugs–I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries. J Clin Epidemiol. 1993;46:1323–30.
8. Zapata E, Zubiaurre L, Bujanda L, Piérola A. Anastrozole-induced hepatotoxicity. Eur J Gastroenterol Hepatol. 2006;18:1233–4.
9. De La Cruz L, Romero-Vazquez J, Jiménez-Sáenz M, Padron JR, Herreiras-Gutierrez JM. Severe acute hepatitis in a patient treated with anastrozole. Lancet. 2007;369:23–4.
10. Laroche M, Borg S, Lassoued S, De Lafontan B, Roché H. Joint pain with aromatase inhibitors: abnormal frequency of Sjogren’s syndrome. J Rheumatol. 2007;34:2259–63.
11. Conti-Beltraminelli M, Pagani O, Ballerini G, Richetti A, Graffeo R, Ruggeri M, Forni V, Pianca S, Schönholzer C, Mainetti C, Cavalli F, Goldhirsch A. Henoch−Schönlein purpura (HSP) during treatment with anastrozole. Ann Oncol. 2007;18:205–7.
12. Morel B, Marotte H, Miossec P. Will steroidal aromatase inhibitors induce rheumatoid arthritis? Ann Rheum Dis. 2007;66:557–8.
13. Sugimoto K, Ito T, Yamamoto N, Shiraki K. Seven cases of autoimmune hepatitis that developed after drug-induced liver injury. Hepatology. 2011;54(5):1892–3. doi:10.1002/hep.24513.
14. Alvarez F, Berg PA, Bianchi FB, Bianchi L, Burroughs AK, Cancado EL, et al. International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol. 1999;31:929–38.
15. Hennes EM, Zeniya M, Czaja AJ, Pares A, Dalekos GN, et al. Simplified criteria for the diagnosis of autoimmune hepatitis. Hepatology. 2008;48:169–76.