Neural Crest and Developmental Exposure to Ethanol

Brain Development: Normal Processes and the Effects of Alcohol and Nicotine

Volumn , Issue , 2006, Pages

  Smith, Susan M ^a   Debelak Kragtorp, Katherine A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84919778198     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1093/acprof:oso/9780195183139.003.0017     Document Type: Chapter

References (110)

1. Able EL (1990) Fetal Alcohol Syndrome. Medical Economics Books, Oradell, NJ.
2. Adickes ED, Mollner TJ, Makoid MC (1993) Terato-genic effects of ethanol during hyperplastic growth in cardiac myocyte cultures. Alcohol Clin Exp Res 17:988-992.
3. Ahlgren SC, Thakur V, Bronner-Fraser M (2002) Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure. Proc Nati Acad Sci USA 99:10476-10481.
4. Ang HL, Deltour L, Hayamizo TF, Zgombic-Knight M, Duester G (1996) Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression. J Biol Chem 271:9526-9534.
5. Astley SJ, Clarren SK (1996) A case definition and photographic screening tool for the facial phenotype of fetal alcohol syndrome. J Pediatr 129:33-41.
6. Astley SJ, Magnuson SI, Omnell LM, Clarren SK (1999) Fetal alcohol syndrome: changes in craniofacial form with age, cognition, and timing of ethanol exposure in the macaque. Teratology 59:163-72.
7. Bannerman P, Nichols W, Puhalla S, Oliver T, Berman M, Pleasure D (2000) Early migratory rat neural crest cells express functional gap junctions:evidence that neural crest cell survival requires gap junction function. J Neurosci Res 61:605-615.
8. Bannigan J, Burke P (1982) Ethanol teratogenicity in mice: a light microscopic study. Teratology 26:247-254.
9. Bannigan J, Cottell D (1984) Ethanol teratogenicity in mice: an electron microscopy study. Teratology 30:281-290.
10. Basch ML, Garcia-Castro MI, Bronner-Fraser M (2004) Molecular mechanisms of neural crest induction. Birth Defects Res Part C 72:109-123.
11. Blader P, Strahle U (1998) Ethanol impairs migration of the prechordal plate in the zebrafish embryo. Dev Biol 201:185-201.
12. Bradley DM, Paiva M, Tonjes LA, Heaton MB (1995) In vitro comparison of the effects of ethanol and acetaldehyde on dorsal root ganglion neurons. Alcohol Clin Exp Res 19:1345-1350.
13. Bruyere HJ, Stith CE (1993) Strain-dependent effect of ethanol on ventricular septal defect frequency in white leghorn chick embryos. Teratology 48:299-303.
14. Bruyere HJ, Stith CE (1994a) Ethyl alcohol reduces cardiac output, stroke volume, and end diastolic volume in the embryonic chick. Teratology 49:104-112.
15. Bruyere HJ, Stith CE, Thorn TA (1994b) Cardioteratogenic dose of ethanol reduces both lactic dehydrogenase and succinic dehydrogenase activity in the bulbar ridges of the embryonic chick heart. J Appl Toxicol 14:27-31.
16. Carey MB, Matsumoto SG (1999) Spontaneous calcium transients are required for neuronal differentiation of murine neural crest. Dev Biol 215:298-313.
17. Carey MB, Matsumoto SG (2000) Calcium transient activity in cultured murine neural crest cells is regulated at the IP(3) receptor. Brain Res 862:201-210.
18. Carones F, Brancato R, Venturi E, Bianchi S, Magni R (1992) Corneal endothelial anomalies in the fetal alcohol syndrome. Arch Ophthalmol 110:1128-1131.
19. Cartwright MM, Smith SM (1995a) Increased cell death and reduced neural crest cell numbers in ethanol-exposed embryos: partial basis for the fetal alcohol syndrome phenotype. Alcohol Clin Exp Res 19:378-386.
20. Cartwright MM, Smith SM (1995b) Stage-dependent effects of ethanol on cranial neural crest cell development: partial basis for the phenotypic variations observed in fetal alcohol syndrome. Alcohol Clin Exp Res 19:1454-1462.
21. Cartwright MM, Tessmer LL, Smith SM (1998) Ethanol-induced neural crest apoptosis is coincident with their endogenous death, but is mechanistically distinct. Alcohol Clin Exp Res 22:142-149.
22. Cavieres MF, Smith SM (2000) Genetic and developmental modulation of cardiac deficits in prenatal alcohol exposure. Alcohol Clin Exp Res 24:102-109.
23. Charness ME, Safran RM, Perides G (1994) Ethanol inhibits neural cell-cell adhesion. J Biol Chem 269:9304-9309.
24. Chen H, Yang JV, Namkung MJ, Juchau MR (1996a) Interactive dysmorphogenic effects of all-trans- retinol and ethanol on cultured whole rat embryos during organogenesis. Teratology 54:12-19.
25. Chen SY, Periasamy A, Yang B, Herman B, Jacobson K, Sulik KK (2000) Differential sensitivity of mouse neural crest cells to ethanol-induced toxicity. Alcohol 20:75-81.
26. Chen SY, Sulik KK (1996) Free radicals and ethanol-induced cytotoxicity in neural crest cells. Alcohol Clin Exp Res 20:1071-1076.
27. Chen SY, Sulik KK (2000) Iron-mediated free radical injury in ethanol-exposed mouse neural crest cells. J Pharmacol Exp Ther 294:134-140.
28. Chen SY, Wilkemeyér MF, Sulik KK, Charness ME (2001) Octanol antagonism of ethanol teratogenesis. FASEBJ 15:1649-1651.
29. Chen SY, Yang B, Jacobson K, Sulik KK (1996b) The membrane disordering effect of ethanol on neural crest cells in vitro and the protective role of GM1 ganglioside. Alcohol 13:589-595.
30. Chou CF, Lai CL, Chang YC, Duester G, Yin SJ (2002) Kinetic mechanism of human class IV alcohol dehydrogenase functioning as retinol dehydrogenase. J BiolChem 277:25209-25516.
31. Church MW, Abel EL, Kaltenbach JA, Overbeck GW (1996) Effects of prenatal alcohol exposure and aging on auditory function in the rat: preliminary results. Alcohol Clin Exp Res 20:172-179.
32. Church MW, Eldis F, Blakley BW, Bawle EV (1997) Hearing, language, speech, vestibular, and dentofacial disorders in fetal alcohol syndrome. Alcohol Clin Exp Res 21:227-237.
33. Clarren SK, Smith DW (1978) The fetal alcohol syndrome. N Engl J Med 298:1063-1067.
34. Daft PA, MC Johnston, KK Sulik (1986) Abnormal heart and great vessel development following acute ethanol exposure in mice. Teratology 33:93-104.
35. Das UG, Cronk CE, Martier SS, Simpson PM, McCarver DG (2004) Alcohol dehydrogenase 2*3 affects alterations in offspring facial morphological associated with maternal ethanol intake in pregnancy. Alcohol Clin Exp Res 28:1598-1606.
36. Davis WL, Crawford LA, Cooper OJ, Farmer GR, Thomas DL, Freeman PB (1990) Ethanol induces the generation of reactive free radicals by neural crest in vitro. J Craniofac Genet Dev Biol 10:277-293.
37. Debelak KA, SM Smith (2000) Avian genetic background modulates the neural crest apoptosis induced by ethanol exposure. Alcohol Clin Exp Res 24:307-314.
38. Debelak-Kragtorp KA, Armant DR, Smith SM (2003) Ethanol-induced cephalic apoptosis requires phopholipase C-dependent intracellular calcium signaling. Alcohol Clin Exp Res 27:515-523.
39. Deltour L, Ang HL, Duester G (1996) Ethanol inhibition of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome. FASEB J 10:1050-1057.
40. Deltour L, Foglio MH, Duester G (1999) Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. J Biol Chem 274:16796-16801.
41. Dickman ED, Thaller C, Smith SM (1997) Temporally regulated retinoic acid depletion produces specific neural crest, ocular, and nervous system defects. Development 124:3111-3121.
42. Dow KE, Riopelle RJ (1990) Specific effects of ethanol on neurite-promoting proteoglycans of neuronal origin. Brain Res 508:40-45.
43. Duester G (1991) A hypothetical mechanism for fetal alcohol syndrome involving ethanol inhibition of retinoic acid synthesis at the alcohol dehydrogenase step. Alcohol Clin Exp Res 15:568-572.
44. Dunty WC, Chen SY, Zucker RM, Dehart DB, Sulik KK (2001) Selective vulnerability of embryonic cell populations to ethanol-induced apoptosis:implications for alcohol-related birth defects and neurodevelopmental disorder. Alcohol Clin Exp Res 25:1523-1535.
45. Edwards HG, Dow-Edwards DL (1991) Craniofacial alterations in adult rats prenatally exposed to ethanol. Teratology 44:373-378.
46. Fang T-T, Bruyere HJ, Kargas SA, Nishikawa T, Takagi Y, Gilbert EF (1987) Ethyl alcohol-induced cardiovascular malformations in the chick embryo. Teratology 35:95-103.
47. Firulli AB, Conway SJ (2004) Combinatorial transcriptional interaction within the cardiac neural crest: a pair of HANDs in heart formation. Birth Defects Res PartC 72:151-161.
48. Fransen E, Lemmon V, Vancamp G, Vits L, Coucke P, Willems PJ (1995) CRASH syndrome-clinical spectrum of corpus callosum hypoplasia, retardation, adducted thumbs, spastic paraparesis and hydrocephalus due to mutations in one signal gene, LI. Eur J Hum Genet 3:273-284.
49. Frias JL, Wilson AL, King GF (1982) A cephalometric study of fetal alcohol syndrome. J Pediatr 191:870-873.
50. Garic-Stankovic A, Hernandez MR, Chiang PJ, Debelak-Kragtorp KA, Flentke GR, Armant DR, Smith SM (2005) Ethanol triggers neural crest apoptosis through the selective activation of a pertussis toxin-sensitive G protein and a phospholipase Cβ-dependent Ca2+ transient. Alcohol Clin Exp Res 29:1237-1246.
51. Garic-Stankovic A, Hernandez MR, Flentke GR, Smith SM (2006) Structural constraints for alcohol-stimulated Ca2+ release in neural crest, and dual agonist/antagonist properties on n-octanol. Alcohol Clin Exp Res in press.
52. Graham A, Francis-West P, Brickell P, Lumsden A (1994) The signaling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest. Nature 372:684-686.
53. Grummer MA, Langhough RE, Zachman RD (1993) Maternal ethanol ingestion effects in fetal rat brain vitamin A as a model for fetal alcohol syndrome. Alcohol Clin Exp Res 17:592-597.
54. Haselbeck RJ, Duester G (1998) ADH4-lacZ transgenic mouse reveals alcohol dehydrogenase localization in embryonic midbrain/hindbrain, otic vesicles, and mesencephalic, trigeminal, facial and olfactory neural crest. Alcohol Clin Exp Res 22:1607-1613.
55. Hassler JA, Moran DJ (1986) Effects of ethanol on the cytoskeleton of migrating and differentiating neural crest cells: possible role in teratogenesis. J Craniofac Genet Dev Biol 2(Suppl): 129-136.
56. Heaton MB, Swanson DJ, Paiva M, Walker DW (1992) Ethanol exposure affects trophic factor activity and responsiveness in chick embryo. Alcohol 9:161-166.
57. Johnson VP, Swayze VW, Sato Y, Andreasen NC (1996) Fetal alcohol syndrome: craniofacial and central nervous system manifestations. Am J Med Genet 61:329-339.
58. Jones KL, Smith DW, Ulleland CN, Streissguth AP (1973) Pattern of malformation in offspring of chronic alcoholic mothers. Lancet 1:1267-1271.
59. Kirby ML (1999) Contribution of neural crest to heart and vessel morphology. In: Harvey RP, Rosenthal N (eds). Heart Development. Academic Press, London, pp 179-193.
60. Kotch LE, Chen SY, Sulik KK (1995) Ethanol-induced teratogenesis: free radical damage as a possible mechanism. Teratology 52:128-136.
61. Kotch LE, Sulik KK (1992a) Experimental fetal alcohol syndrome: proposed pathogenic basis for a variety of associated facial and brain anomalies. Am J Med Genet 44:168-176.
62. Kotch LE, Sulik KK (1992b) Patterns of ethanol-induced cell death in the developing nervous system of mice: neural fold states through the time of anterior neural tube closure. Int J Dev Neurosci 10:273-279.
63. Langston AW, Gudas LJ (1994) Retinoic acid and homeobox gene regulation. Curr Opin Gen Dev 4:550-555.
64. Le Douarin NM, Kalcheim C (1999) The Neural Crest, 2nd Edition. Cambridge University Press, Cambridge, UK.
65. Lemoine P, Harrousseau H, Borteyru JP, Menuet JC (1968) Les enfants de parents alcooliques: anomalies observees a proposos de 127 cas. Ouest Med 21:476-482.
66. Luo J, West JR, Cook RT, Pantazis NJ (1999) Ethanol induces cell death and cell cycle delay in cultures of pheochromocytoma PC 12 cells. Alcohol Clin Exp Res 23:644-656.
67. Maden M, Gale E, Kostetski I, Zile M (1996) Vitamin A deficient quail embryos have half a hindbrain and other neural defects. Curr Biol 6:417-426.
68. Mattson SN, Riley EP, Gramling L, Delis DC, Jones KL (1997) Heavy prenatal alcohol exposure with or without physical features of fetal alcohol syndrome leads to IQ deficits. J Pediatr 131:718-721.
69. McCarver DG, Thomasson HR, Martier SS, Sokol RJ, Li TK (1997) Alcohol dehydrogenase-2*3 allele protects against alcohol-related birth defects among African Americans. J Pharmacol Exp Ther 283:1095-1101.
70. Messing RO, Carpenter CL, Diamond I, Greenberg DA (1986) Ethanol regulates calcium channels in clonal neural cells. Proc Nati Acad Sci USA 83:6213-6215.
71. Mihic SJ, Ye Q, Wick MJ, Koltchine W, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Grennblatt EP, Harris RA, Harrison NL (1997) Sites of alcohol and volatile anaesthetic action on GABAa and glycine receptors. Nature 389:385-389.
72. Miller MT, Beauchamp GR (1988) The role of neural crest cells in fetal alcohol syndrome children with anterior segment anomalies of the eye. Am J Med Genet 4-5(Suppl):180-181.
73. Miller MW, Roskams AJI, Connor JR (1995) Iron regulation in the developing rat brain: effect of in utero ethanol exposure. J Neurochem 65:373-380.
74. Molotkov A, Duester G (2002) Retinol/ethanol drug interaction during acute alcohol intoxication in mice involves inhibition of retinol metabolism to retinoic acid by alcohol dehydrogenase. J Biol Chem. 277:22553-22557.
75. Moore ES, Ward RE, Jamison PL, Morris CA, Bader PI, Hall BD (2001) The subtle facial signs of prenatal exposure to alcohol: an anthropometric approach. J Pediatr 139:215-219.
76. Moore ES, Ward RE, Jamison PL, Morris CA, Bader PI, Hall BD (2002) New perspectives on the face in fetal alcohol syndrome: what anthropometry tells us. Am J Med Genet 109:249-260.
77. Nyquist-Battie C, Freter M (1988) Cardiac mitochondrial abnormalities in a mouse model of the fetal alcohol syndrome. Alcohol Clin Exp Res 12:264-267.
78. Plant MR, MacDonald ME, Grad LI, Ritchie SJ, Richman JM (2000) Locally released retinoic acid repatterns the first branchial arch cartilages in vivo. Dev Biol 222:12-26.
79. Ramanathan R, Wilkemeyer MF, Mittal B, Perides G, Charness ME (1996) Ethanol inhibits cell-cell adhesion mediated by human LI. J Cell Biol 133:381-390.
80. Rasheed A, Hines RN, McCarver DG (1997) Variation in induction of human placental CYP2E1:possible role in susceptibility to fetal alcohol syndrome? Toxicol Appl Pharmacol 144:396-400.
81. Reed JC (2000) Mechanisms of apoptosis. Am J Pathol 157:1415-1430.
82. Rifas L, Towler DA, Avioli LV (1997) Gestational exposure to ethanol suppresses msx2 expression in developing embryos. Proc Nati Acad Sci USA 94:7549-7554.
83. Roebuck TM, Simmons RW, Richardson C, Mattson SN, Riley EP (1998) Neuromuscular responses to disturbance of balance in children with prenatal exposure to alcohol. Alcohol Clin Exp Res 22:1992-1997.
84. Rout UK, Krawetz SA, Armant DR (1997) Ethanol-induced intracellular calcium mobilization rapidly alters gene expression in the mouse blastocyst. Cell Calcium 22:463-474.
85. Rovasio RA, Battiato NL (1995) Role of early migratory neural crest cells in developmental anomalies induced by ethanol. Int J Dev Biol 39:421-422.
86. Rovasio RA, Battiato NL (2002) Ethanol induces morphological and dynamic changes on in vivo and in vitro neural crest cells. Alcohol Clin Exp Res 26:1286-1298.
87. Ruckman RN, Messersmith DJ, O'Brien SA, Getson PR, Boeckx RL, Morse DE (1988) Chronic ethanol exposure in the embryonic chick heart: effect on myocardial function and structure. Teratology 37:317-327.
88. Sanders EJ, Cheung E (1990) Ethanol treatment induces a delayed segmentation anomaly in the chick embryo. Teratology 41:289-297.
89. Sanders EJ, Cheung E, Mahmud E (1987) Ethanol treatment inhibits mesoderm cell spreading in the gastrulating chick embryo. Teratology 36:209-216.
90. Sandor S (1968) The influence of aethyl alcohol on the developing chick embryo. II. Rev Roum d'Embr et de Cyt Série d'Embr 5:167-171.
91. Schneider RA, Hu D, Rubenstein JL, Maden M, Helms JA (2001) Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH. Development 128:2755-2767.
92. Smith SM, Su B, Tessmer LA, Debelak KA, Flentke GR, Hahn SH (2001) Prenatal alcohol exposure redirects sonic hedgehog signaling during craniofacial morphogenesis. Alcohol Clin Exp Res 25:35A.
93. Spong CY, Abebe DT, Gozes I, Brenneman DE, Hill JM (2001) Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome. J Pharmacol Exp Ther 297:774-779.
94. Stachecki JJ, Yelian FD, Schultz JF, Leach RE, Armant DR (1994) Blastocyst cavitation is accelerated by ethanol- or ionophore-induced elevation of intracellular calcium. Biol Reprod 50:1-9.
95. Su B, Debelak KA, Tessmer LL, Cartwright MM, Smith SM (2001) Genetic influences on craniofacial outcome in an avian model of prenatal alcohol exposure. Alcohol Clin Exp Res 25:60-69.
96. Sulik KK, Cook CS, Webster WS (1988) Teratogens and craniofacial malformations: relationships to cell death. Development 103(Suppl):213-232.
97. Sulik KK, Johnston MC, Daft PA, Russell WE, Dehart DB (1986) Fetal alcohol syndrome and DiGeorge anomaly: critical ethanol exposure periods for craniofacial malformations as illustrated in an animal model. Am J Med Genet 2(Suppl):97-l12.
98. Sulik KK, Johnston MC, Webb MA (1981) Fetal alcohol syndrome:embryogenesis in a mouse model. Science 214:936-938.
99. Trainor PA, Ariza-McNaughton L, Krumlauf R (2002) Role of the isthmus and FGFs in resolving the paradox of neural crest plasticity and prepatterning. Science 295:1288-1291.
100. Twal WO, Zile MH (1997) Retinoic acid reverses ethanol-induced cardiovascular abnormalities in quail embryos. Alcohol Clin Exp Res 21:1137-1143.
101. Webster WS, Walsh DA, McEwen SE, Lipson AH (1983) Some teratogenic properties of ethanol and acetaldehyde in C57B1/6J mice: implications for the study of the fetal alcohol syndrome. Teratology 27:231-243.
102. Wedden SE (1987) Epithelial-mesenchymal interactions in the development of chick facial primordia and the target of retinoid action. Development 99:341-351.
103. Wilkemeyer MF, Charness ME (1998) Characterization of alcohol-sensitive and insensitive fibroblast cell lines expressing human L1. J Neurochem 71:2382-2391.
104. Wilkemeyer MF, Chen SY, Menkari CE, Brenneman DE, Sulik KK, Charness ME (2003) Differential effects of ethanol antagonism and neuroprotection in peptide fragment NAPVSIPQ prevention of ethanol-induced developmental toxicity. Proc Nati Acad Sci USA 100:8543-8548.
105. Wilkemeyer MF, Menkari C, Spong CY, Charness ME (2002) Peptide antagonists of ethanol inhibition of L1-mediated cell-cell adhesion. J Pharmacol Exp Ther 303:110-116.
106. Wilkemeyer MF, Sebastian AB, Smith SA, Charness ME (2000) Antagonists of alcohol inhibition of cell adhesion. Proc Nati Acad Sci USA 97:3690-3695.
107. Yao L, Arolfo MP, Dohrman DP, Jiang Z, Fan P, Fuchs S, Janak PH, Gordon AS, Diamond I (2002) βγ-Dimers mediate synergy of dopamine D2 and adenosine A2 receptor-stimulated PKA signaling and regulate ethanol consumption. Cell 109:733-743.
108. Yao L, Fan P, Jiang Z, Mailliard WS, Gordon AS, Diamond I (2003) Addicting drugs utilize a synergistic molecular mechanism in common requiring adenosine and Gi-βγ dinners. Proc Nati Acad Sci USA 100:14379-14384.
109. Zachman RD, Grummer MA (1998) The interaction of ethanol and vitamin A as a potential mechanism for the pathogenesis of fetal alcohol syndrome. Alcohol Clin Exp Res 22:1544-1556.
110. Zile MH (2001) Function of vitamin A in vertebrate embryonic development. J Nutr 131:705-708.