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ChemMedChem

Volumn 10, Issue 1, 2015, Pages 134-143

Targeting a dynamic protein-protein interaction: Fragment screening against the malaria myosin a motor complex

(5) Douse, Christopher H a Vrielink, Nina a Wenlin, Zhang a Cota, Ernesto a Tate, Edward W a

a IMPERIAL COLLEGE LONDON (United Kingdom)

Author keywords

Differential scanning fluorimetry; Fragment screening; Malaria; Myosins; NMR; Protein protein interactions

Indexed keywords

BINDING PROTEIN; CHIMERIC PROTEIN; MYOSIN; MYOSIN A; MYOSIN A TAIL DOMAIN INTERACTING PROTEIN; UNCLASSIFIED DRUG; MYOSIN IIA; PEPTIDE; PROTEIN BINDING; PROTOZOAL PROTEIN;

ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING FLUORIMETRY; FLUOROMETRY; MALARIA; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; BINDING SITE; CHEMISTRY; KINETICS; METABOLISM; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PHASE TRANSITION; PLASMODIUM FALCIPARUM; PROTEIN DENATURATION; PROTEIN DOMAIN; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; FLUOROMETRY; KINETICS; MOLECULAR DYNAMICS SIMULATION; NONMUSCLE MYOSIN TYPE IIA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; PHASE TRANSITION; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTOZOAN PROTEINS;

EID: 84919774360 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201402357 Document Type: Article

Times cited : (17)

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