Cell and molecular determinants of in vivo efficacy of the BH3 mimetic ABT-263 against pediatric acute lymphoblastic leukemia xenografts

Clinical cancer research : an official journal of the American Association for Cancer Research

Volumn 20, Issue 17, 2014, Pages 4520-4531

  Suryani, Santi ^a   Carol, Hernan ^b   Chonghaile, Triona N i ^a   Frismantas, Viktoras ^a   Sarmah, Chintanu ^a   High, Laura ^b   Bornhauser, Beat ^b   Cowley, Mark J ^a   Szymanska, Barbara ^a   Evans, Kathryn ^b   Boehm, Ingrid ^b   Tonna, Elise ^a   Jones, Luke ^a   Manesh, Donya M oradi ^a   Kurmasheva, Raushan T ^a   Billups, Catherine ^b   Kaplan, Warren ^b   Letai, Anthony ^a   Bourquin, Jean Pierre ^a   Houghton, Peter J ^a   Smith, Malcolm A ^a   Lock, Richard B ^a   more..

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANILINE DERIVATIVE; MCL1 PROTEIN, HUMAN; MESSENGER RNA; NAVITOCLAX; PROTEIN BCL 2; PROTEIN MCL 1; SULFONAMIDE; TUMOR PROTEIN;

APOPTOSIS; BIOSYNTHESIS; CHILD; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; PATHOLOGY; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA;

ANILINE COMPOUNDS; APOPTOSIS; CHILD; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NEOPLASM PROTEINS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; SULFONAMIDES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84919686238     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-14-0259     Document Type: Article

References (0)