Safe scale-up of pharmaceutical manufacturing processes with dimethyl sulfoxide as the solvent and a reactant or a byproduct

Organic Process Research and Development

Volumn 18, Issue 12, 2014, Pages 1836-1842

  Wang, Zhe ^a   Richter, Steven M ^a   Bellettini, John R ^a   Pu, Yu Ming ^a   Hill, David R ^a  

^a ABBVIE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYL SULFOXIDE; HAZARDS; RISKS; SOLVENTS;

ALTERNATIVE SOLVENTS; EFFECTIVE MEASURES; EXTERNAL HEATING; HEATING CONTROL; PHARMACEUTICAL MANUFACTURING PROCESS; PROCESS RISKS; SCALE-UP; THERMAL HAZARDS;

ORGANIC SOLVENTS;

EID: 84919647169     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op500260n     Document Type: Article

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