Challenges with antimicrobial susceptibility testing for Neisseria gonorrhoeae in the era of extensively drug-resistant gonorrhoea — Molecular antimicrobial resistance testing crucial

Pathogens and Global Health

Volumn 108, Issue 5, 2014, Pages 215-

  Unemo, Magnus ^a  

^a ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CEFIXIME; CEFTRIAXONE; CEPHALOSPORIN; ANTIINFECTIVE AGENT; CEPHALOSPORIN DERIVATIVE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; DISEASE SURVEILLANCE; GONORRHEA; HUMAN; NEISSERIA GONORRHOEAE; NOTE; PUBLIC HEALTH PROBLEM; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; FEMALE; ISOLATION AND PURIFICATION; MALE; MICROBIAL SENSITIVITY TEST; MULTIDRUG RESISTANCE;

ANTI-BACTERIAL AGENTS; CEPHALOSPORINS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; GONORRHEA; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; NEISSERIA GONORRHOEAE;

EID: 84919631928     PISSN: 20477724     EISSN: 20477732     Source Type: Journal    
DOI: 10.1179/2047772414Z.000000000216     Document Type: Note

References (9)

1. Unemo M, Nicholas RA. Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea. Future Microbiol. 2012; 7: 1401-22.
2. Unemo M, Shafer WM. Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century-past, evolution and future. Clin Microbiol Rev. 2014; 27: 587-613.
3. WorldHealth Organization (WHO), Department ofReproductive Health and Research. Global action plan to control the spread and impact of antimicrobial resistance in Neisseria gonorrhoeae. Geneva: WHO; 2012. p. 1-36.
4. Endimiani A, Guilarte YN, Tinguely R, Hirzberger L, Selvini S, Lupo A, et al. Characterization of Neisseria gonorrhoeae isolates detected in Switzerland (1998-2012): emergence of multidrugresistant clones less susceptible to cephalosporins. BMC Infect Dis. 2014; 14: 106.
5. Tapsall JW, Ndowa F, Lewis DA, Unemo M. Meeting the public health challenge of multidrug-and extensively drugresistant Neisseria gonorrhoeae. Expert Rev Anti Infect Ther. 2009; 7: 821-34.
6. Low N, Unemo M, Jensen JS, Breuer J, Stephenson JM. Molecular diagnostics for gonorrhoea: implications for antimicrobial resistance and the threat of untreatable gonorrhoea. PLoS Med. 2014; 11: e1001598.
7. Goire N, LahraMM, Chen M, Donovan B, Fairley CK, Guy R, et al. Molecular approaches to enhance surveillance of gonococcal antimicrobial resistance. Nat Rev Microbiol. 2014; 12: 223-9.
8. Grad YH, Kirkcaldy RD, Trees D, Dordel J, Harris SR, Goldstein E, et al. Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study. Lancet Infect Dis. 2014; 14: 220-6.
9. Ohnishi M, Unemo M. Phylogenomics for drug-resistant Neisseria gonorrhoeae. Lancet Infect Dis. 2014; 14: 179-80.