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Volumn 9, Issue 1, 2015, Pages 120-124

Inhibition of vascular endothelial growth factor by small interfering RNA upregulates differentiation, Maturation and function of dendritic cells

Author keywords

Cytotoxic T lymphocyte; Dendritic cells; MCF 7; Peripheral blood monouclear cells; Small interfering RNA; Vascular endothelial growth factor

Indexed keywords

B7 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; INTERLEUKIN 4; LIPOFECTAMINE; LIPOSOME; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 84919461176     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2014.2059     Document Type: Article
Times cited : (9)

References (40)
  • 1
    • 0015619335 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution
    • Steinman RM and Cohn ZA: Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J Exp Med 137: 1142-1162, 1973.
    • (1973) J Exp Med , vol.137 , pp. 1142-1162
    • Steinman, R.M.1    Cohn, Z.A.2
  • 2
    • 0031045622 scopus 로고    scopus 로고
    • Origin, maturation and antigen presenting function of dendritic cells
    • Cella M, Sallusto F and Lanzavecchia A: Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol 9: 10-16, 1997.
    • (1997) Curr Opin Immunol , vol.9 , pp. 10-16
    • Cella, M.1    Sallusto, F.2    Lanzavecchia, A.3
  • 3
    • 0030781916 scopus 로고    scopus 로고
    • Dendritic cells: Unique leukocyte populations which control the primary immune response
    • Hart DN: Dendritic cells: unique leukocyte populations which control the primary immune response. Blood 90: 3245-3287, 1997.
    • (1997) Blood , vol.90 , pp. 3245-3287
    • Hart, D.N.1
  • 4
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman RM: The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 9: 271-296, 1991.
    • (1991) Annu Rev Immunol , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 5
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J and Steinman RM: Dendritic cells and the control of immunity. Nature 392: 245-252, 1998.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 6
    • 84880050659 scopus 로고    scopus 로고
    • Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment
    • Baird JR, Fox BA, Sanders KL, et al: Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment. Cancer Res 73: 3842-3851, 2013.
    • (2013) Cancer Res , vol.73 , pp. 3842-3851
    • Baird, J.R.1    Fox, B.A.2    Sanders, K.L.3
  • 7
    • 0030840111 scopus 로고    scopus 로고
    • Dendritic cells as adjuvants for immune-mediated resistance to tumors
    • Schuler G and Steinman RM: Dendritic cells as adjuvants for immune-mediated resistance to tumors. J Exp Med 186: 1183-1187, 1997.
    • (1997) J Exp Med , vol.186 , pp. 1183-1187
    • Schuler, G.1    Steinman, R.M.2
  • 8
    • 0029997017 scopus 로고    scopus 로고
    • Dendritic cells in anti-tumor immune responses. I. Defective antigen presentation in tumor-bearinghosts
    • Gabrilovich D, Ciernik F and Carbone DP: Dendritic cells in anti-tumor immune responses. I. Defective antigen presentation in tumor-bearinghosts. Cell Immunol 170: 101-110, 1996.
    • (1996) Cell Immunol , vol.170 , pp. 101-110
    • Gabrilovich, D.1    Ciernik, F.2    Carbone, D.P.3
  • 9
    • 0029937941 scopus 로고    scopus 로고
    • Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of the T-cell activation
    • Chaux P, Moutet M, Faivre J, Martin F and Martin M: Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of the T-cell activation. Lab Invest 74: 975-983, 1996.
    • (1996) Lab Invest , vol.74 , pp. 975-983
    • Chaux, P.1    Moutet, M.2    Faivre, J.3    Martin, F.4    Martin, M.5
  • 10
    • 0030786569 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats
    • Chaux P, Favre N, Martin M and Martin F: Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats. Int J Cancer 72: 619-624, 1997.
    • (1997) Int J Cancer , vol.72 , pp. 619-624
    • Chaux, P.1    Favre, N.2    Martin, M.3    Martin, F.4
  • 12
    • 0031024123 scopus 로고    scopus 로고
    • Human sunlight-induced basal-cell-carcinoma-associated dendritic cells are deficient in T cell co-stimulatory molecules and are impaired as antigen-presenting cells
    • Nestle FO, Burg G, Fah J, Wrone-Smith T and Nickoloff BJ: Human sunlight-induced basal-cell-carcinoma-associated dendritic cells are deficient in T cell co-stimulatory molecules and are impaired as antigen-presenting cells. Am J Pathol 150: 641-651, 1997.
    • (1997) Am J Pathol , vol.150 , pp. 641-651
    • Nestle, F.O.1    Burg, G.2    Fah, J.3    Wrone-Smith, T.4    Nickoloff, B.J.5
  • 13
    • 0029893672 scopus 로고    scopus 로고
    • Dendritic cells in antitumor immune responses. II. Dendritic cells grown from bone marrow precursors, but not mature DC from tumor-bearing mice are effective antigen carriers in the therapy of established tumors
    • Gabrilovich DI, Nadaf S, Corak J, Berzofsky JA and Carbone DP: Dendritic cells in antitumor immune responses. II. Dendritic cells grown from bone marrow precursors, but not mature DC from tumor-bearing mice are effective antigen carriers in the therapy of established tumors. Cell Immunol 170: 111-119, 1996.
    • (1996) Cell Immunol , vol.170 , pp. 111-119
    • Gabrilovich, D.I.1    Nadaf, S.2    Corak, J.3    Berzofsky, J.A.4    Carbone, D.P.5
  • 14
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • Gabrilovich DI, Chen HL, Girgis KR, et al: Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 2: 1096-1103, 1996.
    • (1996) Nat Med , vol.2 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3
  • 15
    • 0036659945 scopus 로고    scopus 로고
    • Dendritic cells are functionally defective in multiple myeloma: The role of interleukin-6
    • Ratta M, Fagnoni F, Curti A, et al: Dendritic cells are functionally defective in multiple myeloma: the role of interleukin-6. Blood 100: 230-237, 2002.
    • (2002) Blood , vol.100 , pp. 230-237
    • Ratta, M.1    Fagnoni, F.2    Curti, A.3
  • 16
    • 3242779196 scopus 로고    scopus 로고
    • Alpha-fetoprotein impairs APC function and induces their apoptosis
    • Um SH, Mulhall C, Alisa A, et al: Alpha-fetoprotein impairs APC function and induces their apoptosis. J Immunol 173: 1772-1778, 2004.
    • (2004) J Immunol , vol.173 , pp. 1772-1778
    • Um, S.H.1    Mulhall, C.2    Alisa, A.3
  • 17
    • 0037379513 scopus 로고    scopus 로고
    • Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis
    • Péguet-Navarro J, Sportouch M, Popa I, et al: Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis. J Immunol 170: 3488-3494, 2003.
    • (2003) J Immunol , vol.170 , pp. 3488-3494
    • Péguet-Navarro, J.1    Sportouch, M.2    Popa, I.3
  • 18
    • 0036569357 scopus 로고    scopus 로고
    • Prostanoids play a major role in the primary tumor-induced inhibition of dendritic cell differentiation
    • Sombroek CC, Stam AG, Masterson AJ, et al: Prostanoids play a major role in the primary tumor-induced inhibition of dendritic cell differentiation. J Immunol 168: 4333-4343, 2002.
    • (2002) J Immunol , vol.168 , pp. 4333-4343
    • Sombroek, C.C.1    Stam, A.G.2    Masterson, A.J.3
  • 19
    • 84877898781 scopus 로고    scopus 로고
    • Intrinsic immune alterations in renal cell carcinoma and emerging immunotherapeutic approaches
    • Bockorny B and Dasanu CA: Intrinsic immune alterations in renal cell carcinoma and emerging immunotherapeutic approaches. Expert Opin Biol Ther 13: 911-925, 2013.
    • (2013) Expert Opin Biol Ther , vol.13 , pp. 911-925
    • Bockorny, B.1    Dasanu, C.A.2
  • 22
    • 0030498734 scopus 로고    scopus 로고
    • Angiogenesis and metastasis
    • Ellis LM and Fidler IJ: Angiogenesis and metastasis. Eur J Cancer 32A: 2451-2460, 1996.
    • (1996) Eur J Cancer , vol.32A , pp. 2451-2460
    • Ellis, L.M.1    Fidler, I.J.2
  • 23
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N and Davis-Smyth T: The biology of vascular endothelial growth factor. Endocr Rev 18: 4-25, 1997.
    • (1997) Endocr Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 24
    • 1842409593 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor is often elevated in disseminated cancer
    • Salven P, Mänpää H, Orpana A, Alitalo K and Joensuu H: Serum vascular endothelial growth factor is often elevated in disseminated cancer. Clin Cancer Res 3: 647-651, 1997.
    • (1997) Clin Cancer Res , vol.3 , pp. 647-651
    • Salven, P.1    Mänpää, H.2    Orpana, A.3    Alitalo, K.4    Joensuu, H.5
  • 25
    • 84863162400 scopus 로고    scopus 로고
    • Effect of siRNA-mediated downregulation of VEGF in Tca8113 cells on the activity of monocyte-derived dendritic cells
    • Ni YH, Wang ZY, Huang XF, et al: Effect of siRNA-mediated downregulation of VEGF in Tca8113 cells on the activity of monocyte-derived dendritic cells. Oncol Lett 3: 885-892, 2012.
    • (2012) Oncol Lett , vol.3 , pp. 885-892
    • Ni, Y.H.1    Wang, Z.Y.2    Huang, X.F.3
  • 26
    • 84860154891 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C promotes alloimmunity by amplifying antigen-presenting cell maturation and lymphangiogenesis
    • Hajrasouliha AR, Funaki T, Sadrai Z, Hattori T, Chauhan SK and Dana R: Vascular endothelial growth factor-C promotes alloimmunity by amplifying antigen-presenting cell maturation and lymphangiogenesis. Invest Ophthalmol Vis Sci 53: 1244-1250, 2012.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 1244-1250
    • Hajrasouliha, A.R.1    Funaki, T.2    Sadrai, Z.3    Hattori, T.4    Chauhan, S.K.5    Dana, R.6
  • 27
    • 84893712607 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation
    • Marti LC, Pavon L, Severino P, Sibov T, Guilhen D and Moreira-Filho CA: Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation. Mem Inst Oswaldo Cruz 109: 70-79, 2014.
    • (2014) Mem Inst Oswaldo Cruz , vol.109 , pp. 70-79
    • Marti, L.C.1    Pavon, L.2    Severino, P.3    Sibov, T.4    Guilhen, D.5    Moreira-Filho, C.A.6
  • 28
    • 84863671592 scopus 로고    scopus 로고
    • Overexpression and immunosuppressive functions of transforming growth factor 1, vascular endothelial growth factor and interleukin-10 in epithelial ovarian cancer
    • Liu CZ, Zhang L, Chang XH, et al: Overexpression and immunosuppressive functions of transforming growth factor 1, vascular endothelial growth factor and interleukin-10 in epithelial ovarian cancer. Chin J Cancer Res 24: 130-137, 2012.
    • (2012) Chin J Cancer Res , vol.24 , pp. 130-137
    • Liu, C.Z.1    Zhang, L.2    Chang, X.H.3
  • 29
    • 2442668068 scopus 로고    scopus 로고
    • A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
    • Takei Y, Kadomatsu K, Yuzawa Y, Matsuo S and Muramatsu T: A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res 64: 3365-3370, 2004.
    • (2004) Cancer Res , vol.64 , pp. 3365-3370
    • Takei, Y.1    Kadomatsu, K.2    Yuzawa, Y.3    Matsuo, S.4    Muramatsu, T.5
  • 30
    • 84864662070 scopus 로고    scopus 로고
    • Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
    • Walter S, Weinschenk T, Stenzl A, et al: Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med 18: 1254-1261, 2012.
    • (2012) Nat Med , vol.18 , pp. 1254-1261
    • Walter, S.1    Weinschenk, T.2    Stenzl, A.3
  • 31
    • 84859386994 scopus 로고    scopus 로고
    • Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer
    • Cubillos-Ruiz JR, Baird JR, Tesone AJ, et al: Reprogramming tumor-associated dendritic cells in vivo using miRNA mimetics triggers protective immunity against ovarian cancer. Cancer Res 72: 1683-1693, 2012.
    • (2012) Cancer Res , vol.72 , pp. 1683-1693
    • Cubillos-Ruiz, J.R.1    Baird, J.R.2    Tesone, A.J.3
  • 32
    • 0029997017 scopus 로고    scopus 로고
    • Dendritic cells in antitumor immune responses. I. Defective antigen presentation in tumor-bearing hosts
    • Gabrilovich DI, Ciernik IF and Carbone DP: Dendritic cells in antitumor immune responses. I. Defective antigen presentation in tumor-bearing hosts. Cell Immunol 170: 101-110, 1996.
    • (1996) Cell Immunol , vol.170 , pp. 101-110
    • Gabrilovich, D.I.1    Ciernik, I.F.2    Carbone, D.P.3
  • 34
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • Gabrilovich DI, Chen HL, Girgis KR, et al: Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 2: 1096-1103, 1996.
    • (1996) Nat Med , vol.2 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3
  • 35
    • 0036744010 scopus 로고    scopus 로고
    • Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand
    • Mosca PJ, Hobeika AC, Colling K, et al: Multiple signals are required for maturation of human dendritic cells mobilized in vivo with Flt3 ligand. J Leukoc Biol 72: 546-553, 2002.
    • (2002) J Leukoc Biol , vol.72 , pp. 546-553
    • Mosca, P.J.1    Hobeika, A.C.2    Colling, K.3
  • 36
    • 84858793263 scopus 로고    scopus 로고
    • Ovarian cancer progression is controlled by phenotypic changes in dendritic cells
    • Scarlett UK, Rutkowski MR, Rauwerdink AM, et al: Ovarian cancer progression is controlled by phenotypic changes in dendritic cells. J Exp Med 209: 495-506, 2012.
    • (2012) J Exp Med , vol.209 , pp. 495-506
    • Scarlett, U.K.1    Rutkowski, M.R.2    Rauwerdink, A.M.3
  • 37
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • Gabrilovich DI, Chen HL, Girgis KR, et al: Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 2: 1096-1103, 1996.
    • (1996) Nat Med , vol.2 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3
  • 38
    • 0037645137 scopus 로고    scopus 로고
    • Functional modulation of dendritic cells to suppress adaptive immune responses
    • Woltman AM and van Kooten C: Functional modulation of dendritic cells to suppress adaptive immune responses. J Leukoc Biol 73: 428-441, 2003.
    • (2003) J Leukoc Biol , vol.73 , pp. 428-441
    • Woltman, A.M.1    Van Kooten, C.2
  • 39
    • 10844238910 scopus 로고    scopus 로고
    • Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation
    • Dikov MM, Ohm JE, Ray N, et al: Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation. J Immunol 174: 215-222, 2005.
    • (2005) J Immunol , vol.174 , pp. 215-222
    • Dikov, M.M.1    Ohm, J.E.2    Ray, N.3
  • 40
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV and Ferrara N: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246: 1306-1309, 1989.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5


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