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Volumn 64, Issue 22, 2014, Pages 2318-2326

New ischemic stroke and outcomes with vorapaxar versus placebo: Results from the TRA 2°P-TIMI 50 trial

Author keywords

antiplatelet therapy; intracranial hemorrhage; PAR 1; platelet aggregation inhibitors; secondary prevention; thrombin receptor

Indexed keywords

PLACEBO; VORAPAXAR; LACTONE; PYRIDINE DERIVATIVE; THROMBIN RECEPTOR;

EID: 84919458299     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.07.997     Document Type: Article
Times cited : (31)

References (21)
  • 1
    • 84859555815 scopus 로고    scopus 로고
    • Vorapaxar in the secondary prevention of atherothrombotic events
    • TRA 2P-TIMI 50 Steering Committee and Investigators
    • D.A. Morrow, E. Braunwald, M.P. Bonaca TRA 2P-TIMI 50 Steering Committee and Investigators Vorapaxar in the secondary prevention of atherothrombotic events N Engl J Med 366 2012 1404 1413
    • (2012) N Engl J Med , vol.366 , pp. 1404-1413
    • Morrow, D.A.1    Braunwald, E.2    Bonaca, M.P.3
  • 2
    • 84876282305 scopus 로고    scopus 로고
    • Efficacy and safety of vorapaxar in patients with prior ischemic stroke
    • Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events-TIMI 50 Steering Committee and Investigators
    • D.A. Morrow, M.J. Alberts, J.P. Mohr Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events-TIMI 50 Steering Committee and Investigators Efficacy and safety of vorapaxar in patients with prior ischemic stroke Stroke 44 2013 691 698
    • (2013) Stroke , vol.44 , pp. 691-698
    • Morrow, D.A.1    Alberts, M.J.2    Mohr, J.P.3
  • 3
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • TRITON-TIMI 38 Investigators
    • S.D. Wiviott, E. Braunwald, C.H. McCabe TRITON-TIMI 38 Investigators Prasugrel versus clopidogrel in patients with acute coronary syndromes N Engl J Med 357 2007 2001 2015
    • (2007) N Engl J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 4
    • 51449116270 scopus 로고    scopus 로고
    • Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke
    • PRoFESS Study Group
    • R.L. Sacco, H.C. Diener, S. Yusuf PRoFESS Study Group Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke N Engl J Med 359 2008 1238 1251
    • (2008) N Engl J Med , vol.359 , pp. 1238-1251
    • Sacco, R.L.1    Diener, H.C.2    Yusuf, S.3
  • 5
    • 33645737200 scopus 로고    scopus 로고
    • Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: A statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: Co-sponsored by the Council on Cardiovascular Radiology and Intervention: The American Academy of Neurology affirms the value of this guideline
    • American Heart Association/American Stroke Association Council on Stroke; Council on Cardiovascular Radiology and Intervention: American Academy of Neurology
    • R.L. Sacco, R. Adams, G. Albers American Heart Association/American Stroke Association Council on Stroke; Council on Cardiovascular Radiology and Intervention: American Academy of Neurology Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: Co-sponsored by the Council on Cardiovascular Radiology and Intervention: The American Academy of Neurology affirms the value of this guideline Circulation 113 2006 e409 e449
    • (2006) Circulation , vol.113 , pp. 409-e449
    • Sacco, R.L.1    Adams, R.2    Albers, G.3
  • 6
    • 84865485153 scopus 로고    scopus 로고
    • Effects of clopidogrel added to aspirin in patients with recent lacunar stroke
    • SPS3 Investigators
    • SPS3 Investigators O.R. Benavente, R.G. Hart, and L.A. McClure Effects of clopidogrel added to aspirin in patients with recent lacunar stroke N Engl J Med 367 2012 817 825
    • (2012) N Engl J Med , vol.367 , pp. 817-825
    • Benavente, O.R.1    Hart, R.G.2    McClure, L.A.3
  • 7
    • 3242770664 scopus 로고    scopus 로고
    • Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): Randomised, double-blind, placebo-controlled trial
    • H.C. Diener, J. Bogousslavsky, and L.M. Brass Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial Lancet 364 2004 331 337
    • (2004) Lancet , vol.364 , pp. 331-337
    • Diener, H.C.1    Bogousslavsky, J.2    Brass, L.M.3
  • 8
    • 84876295389 scopus 로고    scopus 로고
    • Clopidogrel added to aspirin adds no benefit but bleeding risk in patients with recent lacunar stroke
    • H.C. Diener, and R. Weber Clopidogrel added to aspirin adds no benefit but bleeding risk in patients with recent lacunar stroke Stroke 44 2013 861 863
    • (2013) Stroke , vol.44 , pp. 861-863
    • Diener, H.C.1    Weber, R.2
  • 10
    • 34548201725 scopus 로고    scopus 로고
    • Geographic patterns in overall and specific cardiovascular disease incidence in apparently healthy men in the United States
    • D.Q. Rich, J.M. Gaziano, and T. Kurth Geographic patterns in overall and specific cardiovascular disease incidence in apparently healthy men in the United States Stroke 38 2007 2221 2227
    • (2007) Stroke , vol.38 , pp. 2221-2227
    • Rich, D.Q.1    Gaziano, J.M.2    Kurth, T.3
  • 11
    • 84855353573 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2012 update: A report from the American Heart Association
    • American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • V.L. Roger, A.S. Go, D.M. Lloyd-Jones American Heart Association Statistics Committee and Stroke Statistics Subcommittee Heart disease and stroke statistics - 2012 update: a report from the American Heart Association Circulation 125 2012 e2 e220
    • (2012) Circulation , vol.125 , pp. 2-e220
    • Roger, V.L.1    Go, A.S.2    Lloyd-Jones, D.M.3
  • 12
    • 68949156886 scopus 로고    scopus 로고
    • Evaluation of a novel antiplatelet agent for secondary prevention in patients with a history of atherosclerotic disease: Design and rationale for the thrombin-receptor antagonist in secondary prevention of atherothrombotic ischemic events (TRA 2°P)-TIMI 50 trial
    • TRA 2°P-TIMI 50 Investigators
    • D.A. Morrow, B.M. Scirica, K.A. Fox TRA 2°P-TIMI 50 Investigators Evaluation of a novel antiplatelet agent for secondary prevention in patients with a history of atherosclerotic disease: design and rationale for the thrombin-receptor antagonist in secondary prevention of atherothrombotic ischemic events (TRA 2°P)-TIMI 50 trial Am Heart J 158 2009 335 341.e3
    • (2009) Am Heart J , vol.158 , pp. 335-341e3
    • Morrow, D.A.1    Scirica, B.M.2    Fox, K.A.3
  • 13
    • 84867336413 scopus 로고    scopus 로고
    • Vorapaxar for secondary prevention of thrombotic events for patients with previous myocardial infarction: A prespecified subgroup analysis of the TRA 2°P-TIMI 50 trial
    • TRA 2°P-TIMI 50 Steering Committee Investigators
    • B.M. Scirica, M.P. Bonaca, E. Braunwald TRA 2°P-TIMI 50 Steering Committee Investigators Vorapaxar for secondary prevention of thrombotic events for patients with previous myocardial infarction: a prespecified subgroup analysis of the TRA 2°P-TIMI 50 trial Lancet 380 2012 1317 1324
    • (2012) Lancet , vol.380 , pp. 1317-1324
    • Scirica, B.M.1    Bonaca, M.P.2    Braunwald, E.3
  • 14
    • 0023889706 scopus 로고
    • Interobserver agreement for the assessment of handicap in stroke patients
    • J.C. van Swieten, P.J. Koudstaal, and M.C. Visser Interobserver agreement for the assessment of handicap in stroke patients Stroke 19 1988 604 607
    • (1988) Stroke , vol.19 , pp. 604-607
    • Van Swieten, J.C.1    Koudstaal, P.J.2    Visser, M.C.3
  • 15
    • 44449107747 scopus 로고    scopus 로고
    • Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack
    • American Heart Association; American Stroke Association
    • R.J. Adams, G. Albers, M.J. Alberts American Heart Association; American Stroke Association Update to the AHA/ASA recommendations for the prevention of stroke in patients with stroke and transient ischemic attack Stroke 39 2008 1647 1652
    • (2008) Stroke , vol.39 , pp. 1647-1652
    • Adams, R.J.1    Albers, G.2    Alberts, M.J.3
  • 17
    • 77955014011 scopus 로고    scopus 로고
    • Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study
    • INTERSTROKE Investigators
    • M.J. O'Donnell, D. Xavier, L. Liu INTERSTROKE Investigators Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study Lancet 376 2010 112 123
    • (2010) Lancet , vol.376 , pp. 112-123
    • O'Donnell, M.J.1    Xavier, D.2    Liu, L.3
  • 18
    • 0037065502 scopus 로고    scopus 로고
    • Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients
    • Antithrombotic Trialists' Collaboration Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients BMJ 324 2002 71 86
    • (2002) BMJ , vol.324 , pp. 71-86
  • 19
    • 65849268320 scopus 로고    scopus 로고
    • Aspirin in the primary and secondary prevention of vascular disease: Collaborative meta-analysis of individual participant data from randomised trials
    • Antithrombotic Trialists' (ATT) Collaboration C. Baigent, L. Blackwell, and R. Collins Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials Lancet 373 2009 1849 1860
    • (2009) Lancet , vol.373 , pp. 1849-1860
    • Baigent, C.1    Blackwell, L.2    Collins, R.3
  • 20
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)
    • CAPRIE Steering Committee
    • CAPRIE Steering Committee A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE) Lancet 348 1996 1329 1339
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 21
    • 84879775488 scopus 로고    scopus 로고
    • Clopidogrel with aspirin in acute minor stroke or transient ischemic attack
    • CHANCE Investigators
    • Y. Wang, Y. Wang, X. Zhao CHANCE Investigators Clopidogrel with aspirin in acute minor stroke or transient ischemic attack N Engl J Med 369 2013 11 19
    • (2013) N Engl J Med , vol.369 , pp. 11-19
    • Wang, Y.1    Wang, Y.2    Zhao, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.