Elevated 1-h post-load plasma glucose levels in subjects with normal glucose tolerance are associated with unfavorable inflammatory profile

Acta Diabetologica

Volumn 51, Issue 6, 2014, Pages 927-932

  Sesti, Giorgio ^a   Fiorentino, Teresa Vanessa ^a   Succurro, Elena ^a   Perticone, Maria ^a   Arturi, Franco ^a   Sciacqua, Angela ^a   Perticone, Francesco ^a  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

1 h post load plasma glucose; Glucose tolerance; Inflammatory Score; Subclinical inflammation

Indexed keywords

C REACTIVE PROTEIN; COMPLEMENT COMPONENT C3; FIBRINOGEN; GLUCOSE; GLUCOSE BLOOD LEVEL;

ADULT; ARTICLE; CARDIOMETABOLIC RISK; CONTROLLED STUDY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; PATIENT IDENTIFICATION; RISK ASSESSMENT; AGED; ASYMPTOMATIC DISEASE; CARDIOVASCULAR DISEASES; CHRONIC DISEASE; COMPLICATION; DIABETES MELLITUS, TYPE 2; GLUCOSE TOLERANCE TEST; METABOLISM; METABOLOME; MIDDLE AGED; RISK FACTOR; TIME;

ADULT; AGED; ASYMPTOMATIC DISEASES; BLOOD GLUCOSE; BLOOD SEDIMENTATION; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; CHRONIC DISEASE; COMPLEMENT C3; DIABETES MELLITUS, TYPE 2; FEMALE; FIBRINOGEN; GLUCOSE TOLERANCE TEST; HUMANS; INFLAMMATION; MALE; METABOLOME; MIDDLE AGED; PREDIABETIC STATE; RISK FACTORS; TIME FACTORS;

EID: 84919449457     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-013-0539-x     Document Type: Article

References (38)

1. Tuomilehto J, Lindström J, Eriksson JG et al (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344:1343–1350
2. Knowler WC, Barrett-Connor E, Fowler SE et al (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346:393–403
3. Chiasson JL, Josse RG, Gomis R et al (2002) Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet 359:2072–2077
4. DeFronzo RA, Tripathy D, Schwenke DC et al (2011) Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med 364:1104–1115
5. Chiasson JL, Josse RG, Gomis R et al (2003) Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial. JAMA 290:486–494
6. Ratner R, Goldberg R, Haffner S et al (2005) Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program. Diabetes Care 28:888–894
7. Nathan DM, Davidson MB, DeFronzo RA et al (2007) Impaired fasting glucose and impaired glucose tolerance: implications for care. Diabetes Care 30:753–759
8. Laakso M, Zilinskaite J, Hansen T et al (2008) Insulin sensitivity, insulin release and GLP-1 levels in subjects with IFG and/or IGT in the EUGENE2 study. Diabetologia 51:502–511
9. Cardellini M, Andreozzi F, Laratta E et al (2007) Plasma interleukin-6 levels are increased in subjects with impaired glucose tolerance but not in those with impaired fasting glucose in a cohort of Italian Caucasians. Diabetes Metab Res Rev 23:141–145
10. Unwin N, Shaw J, Zimmet P, Alberti KG (2002) Impaired glucose tolerance and impaired fasting glycemia: the current status on definition and intervention. Diabet Med 19:708–723
11. Abdul-Ghani MA, Abdul-Ghani T, Ali N, Defronzo RA (2008) One-hour plasma glucose concentration and the metabolic syndrome identify subjects at high risk for future type 2 diabetes. Diabetes Care 31:1650–1655
12. Abdul-Ghani MA, Lyssenko V, Tuomi T et al (2009) Fasting versus post-load plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia study. Diabetes Care 32:281–286
13. Succurro E, Marini MA, Arturi F et al (2009) Elevated one-hour post-load plasma glucose levels identifies subjects with normal glucose tolerance but early carotid atherosclerosis. Atherosclerosis 207:245–249
14. Succurro E, Arturi F, Lugarà M et al (2010) One-hour post-load plasma glucose levels are associated with kidney dysfunction. Clin J Am Soc Nephrol 5:1922–1927
15. Bardini G, Dicembrini I, Cresci B, Rotella CM (2010) Inflammation markers and metabolic characteristics of subjects with 1-h plasma glucose levels. Diabetes Care 33:411–413
16. Sciacqua A, Miceli S, Carullo G et al (2011) One-hour post-load plasma glucose levels and left ventricular mass in hypertensive patients. Diabetes Care 34:1406–1411
17. Sciacqua A, Miceli S, Greco L et al (2011) One-hour post-load plasma glucose levels and diastolic function in hypertensive patients. Diabetes Care 34:2291–2296
18. Succurro E, Arturi F, Grembiale A et al (2011) One-hour post-load plasma glucose levels are associated with elevated liver enzymes. Nutr Metab Cardiovasc Dis 21:713–718
19. Marini MA, Succurro E, Frontoni S et al (2012) Insulin sensitivity, β-cell function, and incretin effect in individuals with elevated 1-h postload plasma glucose levels. Diabetes Care 35:868–872
20. Perticone F, Sciacqua A, Tassone EJ et al (2012) One-hour post-load plasma glucose and IGF-1 in hypertensive patients. Eur J Clin Invest 42:1325–1331
21. Perticone F, Sciacqua A, Perticone M et al (2012) Serum uric acid and 1-h postload glucose in essential hypertension. Diabetes Care 35:153–157
22. Sciacqua A, Maio R, Miceli S et al (2012) Association between one-hour post-load plasma glucose levels and vascular stiffness in essential hypertension. PLoS ONE 7:e44470
23. Orencia AJ, Daviglus ML, Dyer AR et al (1997) One hour postload plasma glucose and risks of fatal coronary heart disease and stroke among nondiabetic men and women: the Chicago Heart Association Detection Project in Industry (CHA) Study. J Clin Epidemiol 50:1369–1376
24. Strandberg TE, Pienimäki T, Strandberg AY et al (2011) One-hour glucose, mortality, and risk of diabetes: a 44-year prospective study in men. Arch Intern Med 171:941–943
25. Duncan BB, Schmidt MI, Pinked JS et al (2003) Low-grade systemic inflammation and the development of type 2 diabetes. The arteriosclerosis risk in communities study. Diabetes 52:1799–1805
26. Perticone F, Maio R, Sciacqua A et al (2008) Endothelial dysfunction and CRP are risk factors for diabetes in essential hypertension. Diabetes 57:167–171
27. Emerging Risk Factors Collaboration, Kaptoge S, Di Angelantonio E et al (2012) C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med 367:1310–1320
28. Ridker PM, Wilson PW, Grundy SM (2004) Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation 109:2818–2825
29. Ford ES (2002) Leukocyte count, erythrocyte sedimentation rate, and diabetes incidence in a national sample of US adults. Am J Epidemiol 155:57–64
30. Schmidt MI, Duncan BB, Sharett AR et al (1999) Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study. Lancet 353:1649–1652
31. Engstrom G, Hedblad B, Eriksson KF et al (2005) Complement C3 is a risk factor for the development of diabetes: a population-based cohort study. Diabetes 54:570–575
32. Hess K, Alzahrani SH, Mathai M et al (2013) A novel mechanism for hypofibrinolysis in diabetes: the role of complement C3. Diabetologia 55:1103–1113
33. Matsuda M, De Fronzo RA (1999) Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22:1462–1470
34. Levitan EB, Song Y, Ford ES, Liu S (2004) Is nondiabetic hyperglycemia a risk factor for cardiovascular disease? A meta-analysis of prospective studies. Arch Intern Med 164:2147–2155
35. Abdul-Ghani MA, Williams K, DeFronzo RA, Stern M (2007) What is the best predictor of future type 2 diabetes? Diabetes Care 30:1544–1548
36. Esposito K, Nappo F, Marfella R et al (2002) Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress. Circulation 106:2067–2072
37. Verma S, Wang CH, Li SH et al (2002) A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis. Circulation 106:913–919
38. D’Alessandris C, Lauro R, Presta I, Sesti G (2007) C-Reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport. Diabetologia 50:840–849