-
1
-
-
80055101170
-
The achievement of an early complete cytogenetic response is a major determinant for outcome in patients with early chronic phase chronic myeloid leukemia treated with tyrosine kinase inhibitors
-
quiz 4759
-
Jabbour E, Kantarjian H, O'Brien S, et al. The achievement of an early complete cytogenetic response is a major determinant for outcome in patients with early chronic phase chronic myeloid leukemia treated with tyrosine kinase inhibitors. Blood 2011; 118: 4541-4546; quiz 4759.
-
(2011)
Blood
, vol.118
, pp. 4541-4546
-
-
Jabbour, E.1
Kantarjian, H.2
O'Brien, S.3
-
2
-
-
67650587143
-
Delayed achievement of cytogenetic and molecular response is associated with increased risk of progression among patients with chronic myeloid leukemia in early chronic phase receiving high-dose or standard-dose imatinib therapy
-
Quintas-Cardama A, Kantarjian H, Jones D, et al. Delayed achievement of cytogenetic and molecular response is associated with increased risk of progression among patients with chronic myeloid leukemia in early chronic phase receiving high-dose or standard-dose imatinib therapy. Blood 2009;113:6315-6321.
-
(2009)
Blood
, vol.113
, pp. 6315-6321
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
Jones, D.3
-
3
-
-
77953691179
-
Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
-
Saglio G, Kim DW, Issaragrisil S, et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med 2010;362:2251-2259.
-
(2010)
N Engl J Med
, vol.362
, pp. 2251-2259
-
-
Saglio, G.1
Kim, D.W.2
Issaragrisil, S.3
-
4
-
-
84863011486
-
Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION)
-
Kantarjian HM, Shah NP, Cortes JE, et al. Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION). Blood 2012;119:1123-1129.
-
(2012)
Blood
, vol.119
, pp. 1123-1129
-
-
Kantarjian, H.M.1
Shah, N.P.2
Cortes, J.E.3
-
5
-
-
84919446411
-
Relationship of patient-reported symptoms to daily functioning in chronic myeloid leukemia
-
Williams LA, Ault PS, Garcia-Gonzalez A, et al. Relationship of patient-reported symptoms to daily functioning in chronic myeloid leukemia. Blood 2012; 120(Suppl. 1): Abstract 4260.
-
(2012)
Blood
, vol.120
, pp. 4260
-
-
Williams, L.A.1
Ault, P.S.2
Garcia-Gonzalez, A.3
-
6
-
-
84886719809
-
Cancer drugs in the United States: Justum pretium-the just price
-
May 6. [Epub ahead of print]
-
Kantarjian HM, Fojo T, Mathisen M, et al. Cancer drugs in the United States: justum pretium-the just price. J Clin Oncol 2013 May 6. [Epub ahead of print]
-
(2013)
J Clin Oncol
-
-
Kantarjian, H.M.1
Fojo, T.2
Mathisen, M.3
-
7
-
-
78049528573
-
Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: The prospective, multicentre Stop Imatinib (STIM) trial
-
Mahon FX, Rea D, Guilhot J, et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol 2010; 11: 1029-1035.
-
(2010)
Lancet Oncol
, vol.11
, pp. 1029-1035
-
-
Mahon, F.X.1
Rea, D.2
Guilhot, J.3
-
8
-
-
33846023983
-
Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years
-
Rousselot P, Huguet F, Rea D, et al. Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years. Blood 2007; 109: 58-60.
-
(2007)
Blood
, vol.109
, pp. 58-60
-
-
Rousselot, P.1
Huguet, F.2
Rea, D.3
-
9
-
-
77958012952
-
Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR
-
Ross DM, Branford S, Seymour JF, et al. Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR. Leukemia 2010; 24: 1719-1724.
-
(2010)
Leukemia
, vol.24
, pp. 1719-1724
-
-
Ross, D.M.1
Branford, S.2
Seymour, J.F.3
-
10
-
-
84886917643
-
Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: Results from the TWISTER study
-
Ross DM, Branford S, Seymour JF, et al. Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. Blood 2013; 122: 515-522.
-
(2013)
Blood
, vol.122
, pp. 515-522
-
-
Ross, D.M.1
Branford, S.2
Seymour, J.F.3
-
11
-
-
73349122639
-
Chronic myeloid leukemia: An update of concepts and management recommendations of European LeukemiaNet
-
Baccarani M, Cortes J, Pane F, et al. Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet. J Clin Oncol 2009;27:6041-6051.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6041-6051
-
-
Baccarani, M.1
Cortes, J.2
Pane, F.3
-
12
-
-
0032580320
-
Two-sided conf dence intervals for the single proportion: Comparison of seven methods
-
Newcombe RG. Two-sided conf dence intervals for the single proportion: comparison of seven methods. Stat Med 1998; 17: 857-872.
-
(1998)
Stat Med
, vol.17
, pp. 857-872
-
-
Newcombe, R.G.1
-
13
-
-
34548533007
-
When 100% really isn't 100%: Improving the accuracy of small-sample estimates of completion rates
-
Lewis J, Sauro J. When 100% really isn't 100%: improving the accuracy of small-sample estimates of completion rates. J Usability Stud 2006;1:136-150.
-
(2006)
J Usability Stud
, vol.1
, pp. 136-150
-
-
Lewis, J.1
Sauro, J.2
-
14
-
-
84862136806
-
Discontinuation of imatinib in Japanese patients with chronic myeloid leukemia
-
Takahashi N, Kyo T, Maeda Y, et al. Discontinuation of imatinib in Japanese patients with chronic myeloid leukemia. Haematologica. 2012;97:903-906.
-
(2012)
Haematologica.
, vol.97
, pp. 903-906
-
-
Takahashi, N.1
Kyo, T.2
Maeda, Y.3
-
15
-
-
84862794931
-
Imatinibmesylatediscontinuation in patients with chronic myeloid leukemia who have received front-line imatinib mesylate therapy and achieved complete molecular response
-
Yhim HY, Lee NR, Song EK, et al. Imatinibmesylatediscontinuation in patients with chronic myeloid leukemia who have received front-line imatinib mesylate therapy and achieved complete molecular response. Leuk Res 2012;36:689-693.
-
(2012)
Leuk Res
, vol.36
, pp. 689-693
-
-
Yhim, H.Y.1
Lee, N.R.2
Song, E.K.3
-
16
-
-
84878168513
-
Predictive factors for successful imatinib cessation in chronic myeloid leukemia patients treated with imatinib
-
Lee SE, Choi SY, Bang JH, et al. Predictive factors for successful imatinib cessation in chronic myeloid leukemia patients treated with imatinib. Am J Hematol 2013;88:449-454.
-
(2013)
Am J Hematol
, vol.88
, pp. 449-454
-
-
Lee, S.E.1
Choi, S.Y.2
Bang, J.H.3
-
17
-
-
21744462100
-
Dynamics of chronic myeloid leukaemia
-
Michor F, Hughes TP, Iwasa Y, et al. Dynamics of chronic myeloid leukaemia. Nature 2005;435:1267-1270.
-
(2005)
Nature
, vol.435
, pp. 1267-1270
-
-
Michor, F.1
Hughes, T.P.2
Iwasa, Y.3
-
18
-
-
84870708875
-
Fluctuating values of molecular residual disease (MRD) without molecular progression after imatinib discontinuation in patients (pts) with chronic myeloid leukemia (CML) who have maintained complete molecular response: Implications for re-treatment criteria and role of prior interferon therapy. A pilot study of the French CML Group (FILMC)
-
Rousselot P, Makhoul PC, Rea D, et al. Fluctuating values of molecular residual disease (MRD) without molecular progression after imatinib discontinuation in patients (pts) with chronic myeloid leukemia (CML) who have maintained complete molecular response: implications for re-treatment criteria and role of prior interferon therapy. A pilot study of the French CML Group (FILMC). Blood 2011; 118(Suppl. 1): Abstract 3781.
-
(2011)
Blood
, vol.118
, pp. 3781
-
-
Rousselot, P.1
Makhoul, P.C.2
Rea, D.3
-
19
-
-
75749105885
-
Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: Tyrosine kinase inhibitor optimization and selectivity study
-
Cortes JE, Baccarani M, Guilhot F, et al. Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: tyrosine kinase inhibitor optimization and selectivity study. J Clin Oncol 2010; 28: 424-430.
-
(2010)
J Clin Oncol
, vol.28
, pp. 424-430
-
-
Cortes, J.E.1
Baccarani, M.2
Guilhot, F.3
-
20
-
-
66549108340
-
Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia-positive chronic myeloid leukemia: A European LeukemiaNet Study
-
Baccarani M, Rosti G, Castagnetti F, et al. Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia-positive chronic myeloid leukemia: a European LeukemiaNet Study. Blood 2009;113:4497-4504.
-
(2009)
Blood
, vol.113
, pp. 4497-4504
-
-
Baccarani, M.1
Rosti, G.2
Castagnetti, F.3
-
21
-
-
84866175467
-
Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: Results from the BELA trial
-
Cortes JE, Kim DW, Kantarjian HM, et al. Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: results from the BELA trial. J Clin Oncol 2012;30:3486-3492.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3486-3492
-
-
Cortes, J.E.1
Kim, D.W.2
Kantarjian, H.M.3
-
22
-
-
84880496470
-
Early molecular response and female sex strongly predict stable undetectable BCR-ABL1, the criteria for imatinib discontinuation in patients with CML
-
Branford S, Yeung DT, Ross DM, et al. Early molecular response and female sex strongly predict stable undetectable BCR-ABL1, the criteria for imatinib discontinuation in patients with CML. Blood 2013;121:3818-3824.
-
(2013)
Blood
, vol.121
, pp. 3818-3824
-
-
Branford, S.1
Yeung, D.T.2
Ross, D.M.3
-
23
-
-
84883753798
-
Clinical signif cance of deeper molecular responses with four modalities of tyrosine kinase inhibitors as frontline therapy for chronic myeloid leukemia
-
Falchi L, Kantarjian HM, Quintas-Cardama A, et al. Clinical signif cance of deeper molecular responses with four modalities of tyrosine kinase inhibitors as frontline therapy for chronic myeloid leukemia. Blood 2012; 120(Suppl. 1): Abstract 164.
-
(2012)
Blood
, vol.120
, pp. 164
-
-
Falchi, L.1
Kantarjian, H.M.2
Quintas-Cardama, A.3
-
24
-
-
84860840888
-
Discontinuation of dasatinib or nilotinib in chronic myeloid leukemia (CML) patients (pts) with stable undetectable Bcr-Abl transcripts: Results from the French CML Group (FILMC)
-
Rea D, Rousselot P, Nicolini FE, et al. Discontinuation of dasatinib or nilotinib in chronic myeloid leukemia (CML) patients (pts) with stable undetectable Bcr-Abl transcripts: results from the French CML Group (FILMC). Blood 2011; 118(Suppl. 1): Abstract 604.
-
(2011)
Blood
, vol.118
, pp. 604
-
-
Rea, D.1
Rousselot, P.2
Nicolini, F.E.3
-
25
-
-
33744486584
-
Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction
-
Copland M, Hamilton A, Elrick LJ, et al. Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction. Blood 2006; 107: 4532-4539.
-
(2006)
Blood
, vol.107
, pp. 4532-4539
-
-
Copland, M.1
Hamilton, A.2
Elrick, L.J.3
-
26
-
-
41349083561
-
Ef ective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606
-
Konig H, Holyoake TL, Bhatia R. Ef ective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606. Blood 2008;111:2329-2338.
-
(2008)
Blood
, vol.111
, pp. 2329-2338
-
-
Konig, H.1
Holyoake, T.L.2
Bhatia, R.3
-
27
-
-
0034941132
-
In vivo expansion of the endogenous B-cell compartment stimulated by radiation and serial bone marrow transplantation induces B-cell leukaemia in mice
-
Holyoake TL, Freshney MG, Samuel K, et al. In vivo expansion of the endogenous B-cell compartment stimulated by radiation and serial bone marrow transplantation induces B-cell leukaemia in mice. Br J Haematol 2001;114:49-56.
-
(2001)
Br J Haematol
, vol.114
, pp. 49-56
-
-
Holyoake, T.L.1
Freshney, M.G.2
Samuel, K.3
-
28
-
-
0033568250
-
Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia
-
Holyoake T, Jiang X, Eaves C, et al. Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia. Blood 1999;94:2056-2064.
-
(1999)
Blood
, vol.94
, pp. 2056-2064
-
-
Holyoake, T.1
Jiang, X.2
Eaves, C.3
-
29
-
-
77951632041
-
Relapse and late mortality in 5-year survivors of myeloablative allogeneic hematopoietic cell transplantation for chronic myeloid leukemia in first chronic phase
-
Goldman JM, Majhail NS, Klein JP, et al. Relapse and late mortality in 5-year survivors of myeloablative allogeneic hematopoietic cell transplantation for chronic myeloid leukemia in first chronic phase. J Clin Oncol 2010;28:1888-1895.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1888-1895
-
-
Goldman, J.M.1
Majhail, N.S.2
Klein, J.P.3
-
30
-
-
79953880772
-
Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib
-
Gambacorti-Passerini C, Antolini L, Mahon FX, et al. Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib. J Natl Cancer Inst 2011;103:553-561.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 553-561
-
-
Gambacorti-Passerini, C.1
Antolini, L.2
Mahon, F.X.3
-
31
-
-
80055086681
-
Health-related quality of life in chronic myeloid leukemia patients receiving long-term therapy with imatinib compared with the general population
-
Efcace F, Baccarani M, Breccia M, et al. Health-related quality of life in chronic myeloid leukemia patients receiving long-term therapy with imatinib compared with the general population. Blood 2011; 118: 4554-4560.
-
(2011)
Blood
, vol.118
, pp. 4554-4560
-
-
Efcace, F.1
Baccarani, M.2
Breccia, M.3
|