Correlation between CCR7 expression and lymph node metastatic potential of human tongue carcinoma

Oral Diseases

Volumn 21, Issue 1, 2015, Pages 123-131

  Xia, X ^a   Liu, K ^a   Zhang, H ^a   Shang, Z ^a  

^a Wuhan University   (China)

Author keywords

Chemokine; Chemokine receptor; Human tongue carcinoma; Lymph node metastasis; RNA interference

Indexed keywords

CHEMOKINE RECEPTOR CCR7; SECONDARY LYMPHOID TISSUE CHEMOKINE; VASCULOTROPIN C; CCR7 PROTEIN, HUMAN;

ADULT; AGE; APOPTOSIS; ARTICLE; CANCER GRADING; CANCER STAGING; CARDIOVASCULAR PARAMETERS; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CERVICAL LYMPH NODE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENDER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LYMPH NODE; LYMPH NODE METASTASIS; LYMPHATIC VESSEL DENSITY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TONGUE CARCINOMA; TUMOR VOLUME; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CANCER TRANSPLANTATION; METABOLISM; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; SQUAMOUS CELL CARCINOMA; TONGUE TUMOR; TUMOR CELL LINE;

ADULT; ANIMALS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; HUMANS; LYMPHATIC METASTASIS; MALE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CCR7; TONGUE NEOPLASMS;

EID: 84919436406     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/odi.12228     Document Type: Article

References (34)

1. Balkwill F (2003). Chemokine biology in cancer. Semin Immunol 15: 49-55.
2. Campbell JJ, Butcher EC (2000). Chemokines in tissue-specific and microenvironment-specific lymphocyte homing. Curr Opin Immunol 12: 336-341.
3. Cardones AR, Murakami T, Hwang ST (2003). CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin. Cancer Res 63: 6751-6757.
4. Ding Y, Shimada Y, Maeda M et al (2003). Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma. Clin Cancer Res 9: 3406-3412.
5. Emmett MS, Lanati S, Dunn DB, Stone OA, Bates DO (2011). CCR7 mediates directed growth of melanomas towards lymphatics. Microcirculation 18: 172-182.
6. Forster R, Schubel A, Breitfeld D et al (1999). CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99: 23-33.
7. Issa A, Le TX, Shoushtari AN, Shields JD, Swartz MA (2009). Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype. Cancer Res 69: 349-357.
8. Ivanov K, Som P, Wolf R et al (1999). The back door: venous-mediated metastasis into cervical lymph nodes as an alternative metastatic pathway for oropharyngeal squamous cell carcinoma. Mod Pathol 12: 683-688.
9. Kitadai Y, Amioka T, Haruma K et al (2001). Clinicopathological significance of VEGF-C in human esophageal squamous cell carcinoma. Int J Cancer 93: 662-666.
10. Kunkel EJ, Butcher EC (2002). Chemokines and the tissue-specific migration of lymphocytes. Immunity 16: 1-4.
11. Li J, Sun R, Tao K, Wang G (2011). The CCL21/CCR7 pathway plays a key role in human colon cancer metastasis through regulation of matrix metalloproteinase-9. Dig Liver Dis 43: 40-47.
12. Liu J, Zhang L, Wang C (2012). CCL21 modulates the migration of NSCL cancer by changing the concentration of intracellular Ca2+. Oncol Rep 27: 481-486.
13. Mashino K, Sadanaga N, Yamaguchi H et al (2002). Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma. Cancer Res 62: 2937-2941.
14. Moore MA (2001). The role of chemoattraction in cancer metastases. BioEssays 23: 674-676.
15. Muller A, Homey B, Soto H et al (2001). Involvement of chemokine receptors in breast cancer metastasis. Nature 410: 50-56.
16. Müller A, Homey B, Soto H et al (2001). Involvement of chemokine receptors in breast cancer metastasis. Nature 410: 50-54.
17. Murakami T, Maki W, Cardones AR et al Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells. Cancer Res, 2002;62:7328-7334.
18. Nicolson GL (1993). Paracrine and autocrine growth mechanisms in tumor metastasis to specific sites with particular emphasis on brain and lung metastasis. Cancer Metastasis Rev 12: 325-343.
19. Niki T, Iba S, Tokumou M, Yamada T, Matsuno Y, Hirohashi S (2000). Expression of vascular endothelial growth factor A, B, C and D and their relationship to lymph node status in lung adenocarcinoma. Clin Cancer Res 6: 2431-2439.
20. O-charoenrat P, Pillai G, Patel S et al (2003). Tumour thickness predicts cervical nodal metastases and survival in early oral tongue cancer. Oral Oncol 39: 386-390.
21. Oliveira-Neto HH, de Souza PP, da Silva MR, Mendonça EF, Silva TA, Batista AC (2013). The expression of chemokines CCL19, CCL21 and their receptor CCR7 in oral squamous cell carcinoma and its relevance to cervical lymph node metastasis. Tumour Biol 34: 65-70.
22. Parkin DM, Bray F, Ferlay J, Pisani P (2001). Estimating the world cancer burden: Globocan 2000. Int J Cancer 94: 153-156.
23. Payne AS, Cornelius LA (2002). The role of chemokines in melanoma tumor growth and metastasis. J Invest Dermatol 118: 915-922.
24. Saeki H, Moore AM, Brown MJ, Hwang ST (1999). Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J Immunol 162: 2472-2475.
25. Sobin LH, Wittekind C (2002). TNM: Classification of Malignant Tumours, 6th edn. John Wiley & Sons: New York.
26. Springer TA (1994). Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76: 301-314.
27. Stamper HB Jr, Woodruff JJ (1976). Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules. J Exp Med 144: 828-833.
28. Takanami I (2003). Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis. Int J Cancer 105: 186-189.
29. Till KJ, Lin K, Zuzel M, Cawley JC (2002). The chemokine receptor CCR7 and α4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes. Blood 99: 2977-2984.
30. Tsurusaki T, Kanda S, Sakal H et al (1999). Vascular endothelial growth factor C expression in human prostatic carcinoma and its relationship to lymph node metastasis. Br J Cancer 80: 309-313.
31. Tsuzuki H, Takahashi N, Kojima A et al (2006). Oral and oropharyngeal squamous cell carcinomas expressing CCR7 have poor prognoses. Auris Nasus Larynx 33: 37-42.
32. Wang J, Xi L, Hunt JL et al Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype. Cancer Res. 2004;64:1861-1866.
33. Wilson JL, Burchell J, Grimshaw MJ (2006). Endothelins induce CCR7 expression by breast tumor cells via endothelin receptor A and hypoxia-inducible factor-1. Cancer Res 66: 11802-11807.
34. Zlotnik A, Yoshie O (2000). Chemokines: a new classification system and their role in immunity. Immunity 12: 121-127.