Time outside of therapeutic range in atrial fibrillation patients is associated with long-term risk of dementia

Heart Rhythm

Volumn 11, Issue 12, 2014, Pages 2206-2213

  Jacobs, Victoria ^a   Woller, Scott C ^a   Stevens, Scott ^a   May, Heidi T ^a   Bair, Tami L ^a   Anderson, Jeffrey L ^a   Crandall, Brian G ^a   Day, John D ^a   Johanning, Katie ^a   Long, Yenh ^a   Mallender, Charles ^a   Olson, Jeffrey L ^a   Osborn, Jeffrey S ^a   Weiss, J Peter ^a   Bunch, T Jared ^a  

^a INTERMOUNTAIN MEDICAL CENTER   (United States)

Author keywords

Atrial fibrillation; Dementia; Microbleed; Microembolus; Oral anticoagulation; Stroke; Time in the rapeutic range; Warfarin

Indexed keywords

WARFARIN; ANTICOAGULANT AGENT;

ADULT; AGED; ANTICOAGULANT THERAPY; ARTICLE; CARDIAC PATIENT; CEREBROVASCULAR ACCIDENT; DEMENTIA; DISEASE ASSOCIATION; FEMALE; HEART ATRIUM FIBRILLATION; HIGH RISK PATIENT; HUMAN; ICD-9; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; RETROSPECTIVE STUDY; RISK ASSESSMENT; TIME TO TREATMENT; TRANSIENT ISCHEMIC ATTACK; ATRIAL FIBRILLATION; COHORT ANALYSIS; COMORBIDITY; DOSE RESPONSE; KAPLAN MEIER METHOD; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOPHYSIOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; SEVERITY OF ILLNESS INDEX; SURVIVAL; TIME; TREATMENT OUTCOME; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANTICOAGULANTS; ATRIAL FIBRILLATION; COHORT STUDIES; COMORBIDITY; DEMENTIA; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INTERNATIONAL NORMALIZED RATIO; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TIME FACTORS; TREATMENT OUTCOME; WARFARIN;

EID: 84919435268     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2014.08.013     Document Type: Article

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